Cell-to-Cell Transmission
Virus Cell-to-Cell Transmission
... a cell-free mode or a cell- associated mode involving direct cell-cell ...For cell-free aqueous spreading to be efficient, a virally infected cell would have to release large ...
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Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1.
... revealed cell-cell fu- sions as rapidly as 15 min following cocultivation and the ap- pearance of large balloon-like membrane protrusions within 24 h of coculture ...after cell-to-cell HIV ...
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Productive Entry of HIV-1 during Cell-to-Cell Transmission via Dynamin-Dependent Endocytosis
... during cell-to-cell transmission is consistent with prior observations of cell-free ...that cell-free HIV-1 can productively enter cells in a dynamin-dependent manner via ...
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Apolipoprotein E, but Not Apolipoprotein B, Is Essential for Efficient Cell-to-Cell Transmission of Hepatitis C Virus
... (54% at 72 h p.i. and 40% at 96 h p.i.) than in control cells (18% and 4%, respectively) and ApoB knockdown cells (27% and 10%, respectively) (Fig. 2B). Western blot analysis showed potent de- pletion efficiency by both ...
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GLUT1 Is Not the Primary Binding Receptor but Is Associated with Cell-to-Cell Transmission of Human T-Cell Leukemia Virus Type 1
... productive cell-to-cell transmission of ...magnetic cell sorting beads (Miltenyi, California) for CD4, RNA was isolated, and the amount of HTLV-1 Tax mRNA was quantified by real-time reverse ...
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Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission
... HCV transmission in coculture is resistant to the neutral- izing effects of anti-glycoprotein ...coculture transmission to a panel of anti-E2 glycoprotein antibodies with diverse specific- ities: rodent MAb ...
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A generalized virus dynamics model with cell to cell transmission and cure rate
... Viruses can be spread and transmitted through two fundamental modes, one by virus-to-cell infection and the other by direct cell-to-cell transmission. In this paper, we propose a new ...
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Genetic risk factors of Alzheimer's disease and cell-to-cell transmission of Tau
... the cell-to-cell transmission paradigm now appears to explain how the neurodegenerative pathology spreads between brain regions, the cellular mechanisms of secretion and uptake of misfolded ...
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Cell-to-Cell Transmission Is the Main Mechanism Supporting Bovine Viral Diarrhea Virus Spread in Cell Culture
... the cell membranes, which results in the release of genomic RNA into the cytoplasm of the infected cell ...the cell and diffuse through the extracellular space until they interact with a new host ...
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Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission
... HCV cell-to-cell ...HCV cell-free and cell-to-cell transmission ...HCV cell-free and cell-to-cell spread, we modified the dual-reporter system by replacing ...
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Polarized Cell Migration during Cell-to-Cell Transmission of Herpes Simplex Virus in Human Skin Keratinocytes
... intrinsic cell-to-cell ...HSV-induced cell mi- gration observed in this ...and cell-to-cell transmission in HaCaT ...gray cell (circled 1), virus spreads intercellularly ...
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Inhibitory activity in saliva of cell to cell transmission of human T cell lymphotropic virus type 1 in vitro: evaluation of saliva as an alternative source of transmission
... HTLV-1 transmission. Because HTLV-1 is transmitted only in a cell-to-cell manner (22), the source would need to contain a significant number of infected ...the cell-to-cell ...
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HIV 1 cell to cell transmission and broadly neutralizing antibodies
... cells. Cell-to-cell assays generally rely on CD4 T cell lines or primary cells as the source of ...between cell-free and cell-associated neutralization may be biased by the cell ...
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New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A
... HCV cell-to-cell transmission is dependent on the vesicular ...HCV cell-to-cell ...reduces cell- to-cell transmission, indicating that the regulation by HVR1 of ...
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The effect of bovine BST2A1 on the release and cell to cell transmission of retroviruses
... inhibits cell-to-cell transmission of prototypic foamy virus (PFV), bovine foamy virus (BFV) and bovine immunodefi- ciency virus (BIV), bBST2A1 is inactive against cell-to-cell ...
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Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission
... next cell by traveling through junctional complexes without being intercepted by a neutraliz- ing antibody to the wild-type virus, thus clarifying how cell-to-cell transmission can ...
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Different Requirements for Scavenger Receptor Class B Type I in Hepatitis C Virus Cell-Free versus Cell-to-Cell Transmission
... via cell-to-cell spread, which allows highly efficient virion delivery to neighboring ...superior cell-to cell spread, to its parental genome, J6/JFH-1, with the goal of elucidating the ...
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Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody.
... 2361-2365 0022-538X/89/052361-05$02.00/0 Copyright © 1989, American Society for Microbiology Cell-to-Cell Transmission of Human Immunodeficiency Virus Type 1 in the Presence of Azidothym[r] ...
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Importance of HIV cell-to-cell transmission - implications for neutralizing antibody
... used cell-free virus infection ...vitro cell-to-cell HIV transmission compared to cell-free infection (Li et ...this cell-to-cell HIV transmission model, the ...
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The GP64 envelope fusion protein is an essential baculovirus protein required for cell-to-cell transmission of infection.
... transfected cell line that constitutively expresses the OpMNPV GP64 EFP protein was generated by cotransfection with plasmids encod- ing GP64 EFP and the bacterial neomycin resistance gene, followed by selection ...
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