cellular stress protein regulation
Interplay between hyperosmotic stress and protein kinase a in regulation of ciliary beat frequency in vitro
... In contrast, a hyperosmotic solution of 400mM mannitol reduces CBF significantly. When PKA is inhibited in the presence of mannitol, the abrupt decline in CBF is slightly greater than after perfusion with mannitol alone. ...
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Regulation of the Ferritin H Gene in the Cellular Response to Stress
... nanocage protein that functions to sequester free intracellular iron that may become toxic to the cells ...ferritin protein are controlled by a well-characterized translational repression system in response ...
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Systematic Deletion Analysis of Fission Yeast Protein Kinases
... Eukaryotic protein kinases are key molecules mediating signal transduction that play a pivotal role in the regulation of various biological processes, including cell cycle progression, cellular ...
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<p>Activation of ATM-c-IAP1 Pathway Mediates the Protective Effects of Estradiol in Human Vascular Endothelial Cells Exposed to Intermittent Hypoxia</p>
... compare protein pro fi les among the ...the regulation of cellular stress ...target, cellular inhibitor of apoptosis protein 1 (c-IAP1), were up-regulated by ...
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Identification, Characterization, and Physiologic Analysis of Proteolytic Enzymes in Hyperthermophilic Organisms
... motility, cellular competence, and pathogenesis (117). During dynamic heat stress, ...suppressor protein (DksA) ...during stress response ...vital cellular role, changes in ...
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Identification of YbeY Protein Interactions Involved in 16S rRNA Maturation and Stress Regulation in Escherichia coli
... affecting cellular viability, stress tolerance, and pathogenic and symbiotic behavior of ...numerous protein or RNA partners that are involved in various aspects of cellular ...somal ...
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Redox Regulation, Rather than Stress Induced Phosphorylation, of a Hog1 Mitogen Activated Protein Kinase Modulates Its Nitrosative Stress Specific Outputs
... mitogen-activated protein kinases (MAPKs) play critical roles in cellular responses to environmental ...the stress-specific outputs of MAP kinases? We find that the Hog1 MAPK contributes to ...
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S nitrosylation of the thioredoxin like domains of protein disulphide isomerase and its role in neurodegenerative conditions
... of protein aggregates strongly features in PD pathol- ...where protein aggregation and increased cellular stress, among others, contribute to disease pathology (reviewed in Nakamura and ...
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Spy1 Regulation of the DNA Damage Response; Checkpoint Activation and Cellular Senescence
... oxidative stress [6]. Replicative senescence is a specialized cellular mechanism which occurs following an extended period of proliferation of normal cells driven by excessive telomere erosion and ...
213
Heat Shock Protein 70 Regulates Degradation of the Mumps Virus Phosphoprotein via the Ubiquitin-Proteasome Pathway
... Hsp72 is nonessential for MuV replication but suppresses apoptotic cell death of MuV-infected cells. To determine the roles of Hsp72 in MuV infection, the expression of Hsp72 was suppressed by Hsp72-specific siRNAs ...
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Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp Strain PCC 6803: Insights from Transcriptomic, Fluxomic, and Physiological Analyses
... other cellular processes (such as protein and peptide secretion, cell division, detoxification, and chemotaxis) are almost equally dis- tributed across these two ...
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Molecular biology of cantharidin in cancer cells
... The microarray analyses were used to find the genes responsible for the action of cantharidin. These studies showed that many apoptosis-related genes and genes involved in DNA damage and repair correlated with the IC 50 ...
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Cerebral lactate metabolism and memory: Implications for Alzheimer's disease
... meet cellular energy ...up- regulation of PKM2 and promotes cell proliferation 336 ...several cellular responses that are beneficial for a growing tumor, including vascular remodelling, increased ...
229
Regulation of adenovirus and cellular gene expression and of cellular transformation by the E1B-encoded 175-amino-acid protein.
... These differences may be explained as follows: i the expression of additional viral or cellular genes or both during a virus infection could diminish the role of the E1B 175R protein in [r] ...
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Protein kinase CK2 in the ER stress response
... oxidative stress, hypoxia, energy deprivation, metabolism or pro- tein ...ER, cellular signalling pathways are induced in order to start an adaptive cellular ...
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Evolution of the cellular stress proteome: from monophyletic origin to ubiquitous function
... the cellular stress response ...towards stress, but also contain particular highly specialized tissues capable of withstanding extreme ...environmental stress provide a good example (Woo and ...
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9-24-2014 12:00 AM The Role Of The RNA-Binding Protein Rho Guanine Nucleotide Exchange Factor In The Cellular Stress Response
... misfolded protein that are not specific to ALS pathology, but have been observed in a diverse number of neurodegenerative disorders (for example, Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease) ...
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Rice UBC13, a candidate housekeeping gene, is required for K63-linked polyubiquitination and tolerance to DNA damage
... While plant growth and reproduction is dependent on sunlight, UV irradiation from sunlight is one of the major genotoxic stresses that threaten plant survival and genome stability. In addition, many environmental ...
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DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease
... the stress markers used in this study raises the ques- tion of whether the cerebellar dentate nuclear involve- ment is present from the beginning of the disease or is, instead, a later symptom of disease ...
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Molecular basis of cardiac performance Plasticity of the myocardium generated through protein isoform switches
... Thus, similar to the mitogenic response of a variety of cell types, induction of the cellular protooncogenes and major stress protein genes reflect early changes occurring in the nuclei [r] ...
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