cerebral ischemia-reperfusion
Original Article Neuroprotective effects of resveratrol against cerebral ischemia/reperfusion injury in rats through attenuation of inflammation
... Cerebral ischemia/reperfusion (I/R) injury is closely related to stroke, which is a serious dis- ease with poor blood flow to the ...major cerebral artery is blocked by a thrombus or embolism ...
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Original Article Neuroprotective effect of A2AR knockout on cerebral ischemia/reperfusion injury via the inhibition of microglia activation
... Focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO) for 30 min in mild mice and A2AR knockout mice followed by 1 d, 3 d, and 7 d ...with cerebral ...
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Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats
... Cerebral ischemia/reperfusion (I/R) injury is a critical factor leading to a poor prognosis for ischemic stroke ...on cerebral I/R injury in rats. Cerebral I/R caused by middle ...
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Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats
... Results: Our results showed that curdione could significantly reduce the infarct size and neuro- logical deficits, promote cognitive function recovery and recover neuronal morphologic damages in MCAO rats. It also ...
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Original Article Role of miRNA-185 in cerebral ischemia-reperfusion injury
... Rats were fasted 24 hours before surgery with free drinking water. 30 rats were anesthetized by intraperitoneal injection with 10 percent of chloral hydrate at the dose of (weight * 3 + 0.1) ml. Then, the common carotid ...
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Original Article Effects of electroacupuncture at Shenting and Baihui on cAMP-PKA-CREB signaling pathways in rats with cognitive dysfunction caused by cerebral ischemia reperfusion
... Abstract: Background: This study aimed to explore the effects of electroacupuncture at Shenting (Governor Ves- sel (GV) 24) and Baihui (GV 20) acupoints on rat behavior and the mechanisms of electroacupuncture on change ...
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Original Article Activation of STAT3 is involved in neuronal apoptosis in focal cerebral ischemia/reperfusion rats via Bcl 2/Fas pathway
... focal cerebral ischemia/reperfusion ...of cerebral infarction was measured by TCC ...of reperfusion following 3 h of middle cerebral artery occlusion (MCAO), and the neuronal ...
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TREM2 protects against cerebral ischemia/reperfusion injury
... of cerebral ischemia injury, the role of triggering receptor expressed on myeloid cells 2 (TREM2) in the pathogenesis of ischemic stroke remains to be ...the cerebral cortex after middle ...
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NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
... Global Cerebral Ischemia/Reperfusion Injury in ...global cerebral ischemia on Swiss albino mice by carotid artery occlusion for 17 min followed by 24 h ...the ...
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ASSESMENT OF THE ANTI INFLAMMATORY EFFECT OF CINEOL ON CEREBRAL ISCHEMIA REPERFUSION I/R INJURY
... global cerebral ischemia reperfusion injury cause an extensive growth in the mRNA expression levels of TNF-α and IL-6 in the rat ...transient cerebral ischemia and the release of ...
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Original Article Bumetanide protects focal cerebral ischemia-reperfusion injury in rat
... attenuate ischemia-evoked cerebral ...protect cerebral ischemia-reperfusion injury (IRI) in vivo is ...attenuate cerebral IRI and if its protection effect might be related to the ...
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Effects of vagus nerve stimulation on cognitive functioning in rats with cerebral ischemia reperfusion
... a cerebral ischemia/reperfusion (I/R) injury model in ...and reperfusion of the middle cerebral artery (MCAO/R) in Sprague–Dawley ...
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Original Article Xanthotoxol inhibits cerebral ischemia/reperfusion injury-induced hippocampal neuronal cell apoptosis through suppressing the p38 MAPK and JNK signaling pathways
... Therefore, alterations in the levels of anti- and pro-apoptotic proteins influence apoptosis [18]. Caspases play a critical role in the regulation of cell apoptosis [19]. Among the caspases, the effector caspase-3 has ...
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Original Article Pathways and protective mechanisms for cerebral ischemia-reperfusion injuries in mice
... texes. They also demonstrated the crucial pro- tective roles of GPX1 during IRI, particularly through the downplay of Nrf2-mediated cyto- protective pathways and ubiquitin-proteasome system dysfunction (UPS) function. ...
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Original Article Atorvastatin protects mouse brain against cerebral ischemia/reperfusion injury via down-regulating MMP-2 and MMP-9 expression
... Middle cerebral artery occlusion model was established in the mice of MCAO/R + PBS and MCAO/R + atorvastatin groups before the drug ...middle cerebral artery (MCA) via the external carotid ...
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... from lipid peroxidation. As they are very short-lived, the direct measurement of free radicals is extremely diffi- cult. Measured MDA levels provide information about the damage induced by free radicals [, ]. ...
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Original Article Baicalin protects against thrombin induced cell injury in SH-SY5Y cells
... [10, 11]. PARs are a family of seven transmem- brane G protein-coupled receptors that include PAR-1, PAR-2, PAR-3 and PAR-4. Of these differ- ent receptors, PAR-1, PAR-3, and PAR-4 can be activated by thrombin, whereas ...
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EVALUATION OF ANNONA SQUAMOSA LINN LEAF EXTARACT ON EXPERIMENTALLY INDUCED CEREBRAL ISCHEMIC REPERFUSION INJURY IN ALBINO WISTAR RATS
... induced cerebral ischemia reperfusion injury in rat model pre treatment with Aqueous and Ethyl ...in cerebral protection in terms of reduction of infarct size of brain tissue, Decrease in ...
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Original Article Knockdown of tissue inhibitor of metalloproteinase 1 suppresses cell apoptosis in cerebral infarction rat model
... middle cerebral artery occlusion (MCAo)-induced cerebral ischemia/reperfusion rabbit model [17], whereas the specific role of TIMP1 during cerebral infarction is ...in cerebral ...
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Vol 70, No 2 (2018)
... against cerebral ischemia-reperfusion injury ...middle cerebral artery occlusion (MCAO) for 60 min followed by 24 h of reperfusion (IRI-induced); group III – pretreated with PPY (100 ...
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