cerebral ischemia/reperfusion injury
Adjudin protects against cerebral ischemia reperfusion injury by inhibition of neuroinflammation and blood-brain barrier disruption
... in ischemia reperfusion ...middle cerebral artery occlusion (tMCAO) ...after reperfusion significantly decreased the infarction volume and neuroscore compared to the vehicle ...after ...
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<p>Deltonin Ameliorates Cerebral Ischemia/Reperfusion Injury in Correlation with Modulation of Autophagy and Inflammation</p>
... in ischemia-reperfusion (I/R) ...against ischemia-reperfusion injury through the activation of PI3K/AKT/mTOR ...by cerebral ischemia/reperfusion injury, as ...
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Qingkailing injection ameliorates cerebral ischemia reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway
... Cerebral ischemia diminishes the oxygen supply, which damages the brain cells leading to neurological dysfunction and cerebral ...of cerebral ischemia, and more efficient agents to ...
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TREM2 protects against cerebral ischemia/reperfusion injury
... of cerebral ischemia injury, the role of triggering receptor expressed on myeloid cells 2 (TREM2) in the pathogenesis of ischemic stroke remains to be ...the cerebral cortex after middle ...
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Original Article Therapeutic effects of moxibustion precondition on cerebral ischemia-reperfusion injury in rats
... on cerebral ischemia-reperfu- sion injury in ...reduce cerebral ischemia reperfusion injury in rats, and decrease the expression of miRNA664 and ...
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Original Article Role of GRP78, CHOP and TRB3 in cerebral ischemia-reperfusion injury in rats
... After cerebral ischemia, some of the blood vessels spontaneously recanalize, and some are recanalized after thrombolysis, cell damage further aggravates, and cerebral ischemia ...
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Original Article Effects and mechanisms of dexmedetomidine on apoptosis of hippocampal neurons in rats with cerebral ischemia-reperfusion injury
... with cerebral ischemia-reperfusion injury ...and cerebral infarct area was detected by 2,3,5-triphenyltetrazolium chloride (TTC) ...scores, cerebral infarct area, and water ...
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Inhibition of T cell immunoglobulin and mucin-1 (TIM-1) protects against cerebral ischemia-reperfusion injury
... thought to have acute detrimental and delayed protect- ive effects [9]. The family of T cell immunoglobulin and mucin domain (TIM) proteins are type 1 transmem- brane proteins, including eight mouse proteins (TIM-1 - ...
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Protective effect of levothyroxine on myocardial and cerebral ischemia reperfusion injury during surgery under cardiopulmonary bypass
... and cerebral ischemia reperfusion injury during surgery under cardiopulmonary ...and cerebral injury indexes, pro- inflammatory and adhesion molecules as well as antioxidant ...
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Original Article Role of miRNA-185 in cerebral ischemia-reperfusion injury
... in cerebral ischemia-reperfusion ...The cerebral ischemia-reperfusion rat model was established by clipping common carotid ...of cerebral cortex cells in ...rat ...
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NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
... Global Cerebral Ischemia/Reperfusion Injury in ...global cerebral ischemia on Swiss albino mice by carotid artery occlusion for 17 min followed by 24 h ...the ...
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Original Article Bumetanide protects focal cerebral ischemia-reperfusion injury in rat
... attenuate ischemia-evoked cerebral ...protect cerebral ischemia-reperfusion injury (IRI) in vivo is ...attenuate cerebral IRI and if its protection effect might be related ...
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Ursolic acid reduces the metalloprotease/anti-metalloprotease imbalance in cerebral ischemia and reperfusion injury
... UA treatment. The levels of pp38, pERK1/2, and pJNK1/2 were elevated in the control group compared with the sham group, and UA inhibited p38, ERK1/2, and JNK1/2 activation in a dose-dependent manner. These results ...
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Original Article Neuroprotective effects of resveratrol against cerebral ischemia/reperfusion injury in rats through attenuation of inflammation
... It has been shown that NF-κB mediates the transcription of a large number of genes, such as TNF-α, IL-1β, IL-6 and iNOS, the products of which are known to play important roles in the pathogenesis of cerebral ...
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Original Article Puerarin modulates autophagy to ameliorate cerebral ischemia/reperfusion injury through JNK signaling pathway
... Thrombolysis, antiplatelet agents, and antico- agulants are considered the main rational ther- apies for ischemic stroke in a timely fashion and the tissue-type plasminogen activator (rt- PA) is appropriate for patients ...
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Original Article Neuroprotective effect of A2AR knockout on cerebral ischemia/reperfusion injury via the inhibition of microglia activation
... First, cerebral ischemia/reperfusion trig- ger microglial activation and A2AR knockout were inhibited the activity of microglia as evi- denced by decreasing microglial Iba1 ...
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Original Article Icariin protects against cerebral ischemia/reperfusion injury by activating the PI3K/Akt signaling pathway
... Icariin has been reported to exhibit a wide range of pharmacological effects. Pan et al. suggested that icariin possessed an antide- pressant-like property [19]. Nian et al. reported that icariin has a definite ...
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Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats
... After the indicated treatments, the rats were transcardially perfused with ice-cold PBS. Then the brain was quickly removed and frozen in stainless steel brain matrices (− 20 °C) for 10 min, and the cerebellum and ...
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Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
... during cerebral I/R injury, and found that the diazoxide could inhibit the activation of NLRP3 inflammasome, which indicated that mitochon- drial dysfunction played a great role in activating NLRP3 ...
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A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury
... min. Reperfusion was established when the filament was withdrawn back to the common ca- rotid ...the cerebral blood flow (CBF) for 5 min both before and after MCAO, as well as during reperfusion for ...
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