chromosomal rearrangement
Cryptic breakpoint identified by whole-genome mate-pair sequencing in a rare paternally inherited complex chromosomal rearrangement
... complex chromosomal rearrangements in non- affected individuals is crucial as they may result in reproductive failure, recurrent miscarriages or affected ...complex chromosomal rearrangement ...the ...
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Characterization of a complex chromosomal rearrangement using chromosome, FISH, and microarray assays in a girl with multiple congenital abnormalities and developmental delay
... Complex chromosomal rearrangements (CCRs) are balanced or unbalanced structural rearrangements involving three or more cytogenetic breakpoints on two or more chromosomal ...complex chromosomal ...
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Preferential clustering of viral DNA sequences at or near the site of chromosomal rearrangement in fowl adenovirus type 1 DNA-transformed cell lines.
... Previous in situ hybridization analyses on an FAV-1 induced tumor and on two human adenovirus-transformed cell lines 19, 22 showed that viral DNA sequences resided on chromosomes of host[r] ...
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A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var grubii Type Strain Enhances Key Phenotypes Associated with Virulence
... this rearrangement since its isolation from a human clinical ...a chromosomal translocation that directly interrupts two genes, which all descendants of this strain from various research laboratories appear ...
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Identification of a balanced complex chromosomal rearrangement involving chromosomes 3, 18 and 21 with recurrent abortion: case report
... Although CCRs are rarely found in screened populations, they are often associated with mental retardation, conge- nital abnormalities, recurrent spontaneous abortions and infertility [14-16]. The application of FISH and ...
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De novo complex intra chromosomal rearrangement after ICSI: characterisation by BACs micro array-CGH
... Hybridized micro arrays were analysed with GenePix 4000B scanner (Axon Instruments Inc., Union City, CA, USA). Cy3 and Cy5 images were scanned separately through two different channels. Two 16 bit TIFF images were ...
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The naturally occurring alleles of MAL1 in Saccharomyces species evolved by various mutagenic processes including chromosomal rearrangement.
... Maureen J. Each dominant MAL locus thus far analyzed contains three genes: GENE 1, encoding maltose permease, GENE 2 encoding maltase and GENE 3 encoding a positive tr[r] ...
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Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2
... We used Affymetrix gene expression arrays to compare the expression levels of genes in and around the mapped breakpoints in the parents, a sibling and the proband, on RNA extracted from [r] ...
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Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.
... To study the cellular genes involved in the transformation of interleukin-3 IL-3-dependent hematopoietic progenitor cells, we have isolated a series of cell lines from Moloney leukemia v[r] ...
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Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis
... Clonal evolution with additional chromosomal ab- normalities besides t(9;22) is considered as a feature of disease progression in CML. The predominant emer- gence of 11q23 in BP (8/11) suggests that 11q23/ MLL may ...
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Marfan syndrome with a complex chromosomal rearrangement including deletion of the FBN1 gene
... chromosome rearrangement among chromosomes 6, 12 and ...a chromosomal rearran- gement, both complex and reciprocal translocations, show an imbalance on the chromosomal or molecular level as an ...
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A familial chromosomal complex rearrangement confirms RUNX1T1 as a causative gene for intellectual disability and suggests that 1p22.1p21.3 duplication is likely benign
... In the present study, we report on a patient presenting with severe anemia, splenomegaly, mild intellectual disabil- ity and facial dysmorphisms and harboring a double imbal- ance resulting from malsegregation of a ...
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Chromosomal Speciation Revisited: Modes of Diversification in Australian Morabine Grasshoppers (Vandiemenella, viatica Species Group).
... Australian morabine grasshoppers genus Vandiemenella, viatica species group are an excellent model for studying the role of chromosomal rearrangement in speciation because they show exte[r] ...
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Transgene Coplacement and High Efficiency Site-Specific Recombination With the Cre/loxP System in Drosophila
... ORBAN, P. BAKER, 1995 A system for inser- tional mutagenesis and chromosomal rearrangement using the Ds transposon and Cre-lox. GEWR, 1992 Position-indepen- dent germlin[r] ...
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Comparative Genomics, Marker Density and Statistical Analysis of Chromosome Rearrangements
... of chromosomal breakpoints that have arisen ...chromosomal rearrangement. The model treats all modes of chromosome rearrangement alike, and it assumes that chromosome boundaries and ...
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Prenatal identification of partial 3q duplication syndrome
... of chromosomal rearrangement, which allowed the identification of the origin of the additional genetic material in the foetus and the previous malformed child of the same ...
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Development of the Lewis acid catalyzed Allenoate Claisen rearrangement Investigations of enantioselective catalysis of the Allenoate Claisen rearrangement Studies towards the total synthesis of erythrolide E
... The development of a new Lewis acid catalyzed sigmatropic reaction is described. This process, termed the allenoate-Claisen rearrangement, involves the metal-catalyzed condensation of an allenic ester with a ...
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A novel diterpene lactone
... (2). Under Baeyer±Villiger rearrangement conditions, 2.5 ml of hydrogen peroxide (30%), dissolved in anhydrous dichloromethane (15 ml), and 14 ml of anhydrous tri¯uoroacetic acid were added to a solution of 0.66 ...
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The Structural Elucidation of a Proposed Intermediate in the Stereoselective Synthesis of dl Desoxypodocarpic Acid
... 5-isopodocarpic acid series with the corresponding compounds in the rearrangement product series indicates that the rearrangement product cannot be the corresponding trans-fused diosphen[r] ...
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Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome
... Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome Matthew[.] ...
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