Chronic granulomatous disease (CGD)
Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease
... with chronic granulomatous disease (CGD) exhibit metabolic and bactericidal deficiencies that may be the result of inadequate production of H 2 O 2 ...
7
Chronic Recurrent Multifocal Osteomyelitis and Thalidomide in Chronic Granulomatous Disease
... Chronic granulomatous disease (CGD) is a primary immunodeficiency that leads to severe recurrent infection and inflammatory complications that are usually difficult to diagnose and ...in ...
7
Degranulation of leukocytes in chronic granulomatous disease
... with chronic granulomatous disease ...resting CGD and normal cells were very similar for acid and alkaline phosphatase and peroxidase, but the proportion of beta glucuronidase in the granule ...
7
Coregulation of NADPH oxidase activation and phosphorylation of a 48 kD protein(s) by a cytosolic factor defective in autosomal recessive chronic granulomatous disease
... of chronic granulomatous disease (CGD) to examine the role of protein phosphorylation in activation of NADPH oxidase in a cell-free ...from CGD PMN plus SDS expressed little NADPH ...
13
Recombinant interferon gamma augments phagocyte superoxide production and X chronic granulomatous disease gene expression in X linked variant chronic granulomatous disease
... of chronic granulomatous disease (CGD) by studying its effects on CGD phagocyte superoxide generation, NADPH oxidase kinetics, cytochrome b559 content, and expression of X-CGD ...
9
Mechanisms of antibody dependent cellular cytotoxicity: the use of effector cells from chronic granulomatous disease patients as investigative probes
... from chronic granulomatous disease (CGD) patients. CGD phagocytic cells (neutrophils and monocytes) had depressed ADCC activity against antibody-coated human erythrocyte (HRBC) targets ...
10
CHRONIC GRANULOMATOUS DISEASE: CORRELATION BETWEEN PATHOGENESIS AND CLINICAL FINDINGS
... drogen peroxide antibacterial system. : Quantita- tive nitroblue tetrazoliiiii, test in chronic granuloniatous disease. A.: Chronic granulomatous disease in females: A deficiency of leuk[r] ...
12
Cytochrome b deficiency in an autosomal form of chronic granulomatous disease A third form of chronic granulomatous disease recognized by monocyte hybridization
... autosomal because the granulocytes of both parents (first cousins) and a nonaffected sister of the patients expressed 70-80% of the normal cytochrome b signal, showed low-normal or subnormal oxidative reactions during ...
7
Continuous Antibiotic Therapy in Chronic Granulomatous Disease: Preliminary Communication
... Continuous Antibiotic Therapy in Chronic Granulomatous Disease: Preliminary. Services[r] ...
5
Lupus Erythematosus and Chronic Granulomatous Disease: Report of Four Iranian Patients with AR-CGD and One XL-CGD
... inherited disease with phagocytic granulocyte disfunction, caused by defects in oxidative metabolism of phagocytic ...with CGD indicated that various pathological conditions; especially auto–immune ...
7
Gastrointestinal Involvement in Chronic Granulomatous Disease
... Crohn’s disease, the granulomata in CGD colitis were sharply defined aggregates of epithelioid his- tiocytes surrounded by a cuff of dense lymphocytic ...of chronic colitis, including Paneth cell ...
9
Sarcoidosis in Chronic Granulomatous Disease
... with CGD has not been ...with CGD, we measured ACE levels in 26 other age-matched patients with CGD (CGD reference, age ⬎ 8 years), in- cluding those with or without significant intercurrent ...
8
Nocardia farcinica Pneumonia in Chronic Granulomatous Disease
... with CGD are ...The disease dis- seminated to the bone (3 cases), brain (2 cases), skin/ soft tissue (2 cases), lymph nodes (1 case), and liver (1 ...
6
Leukotriene biosynthesis by polymorphonuclear leukocytes from two patients with chronic granulomatous disease
... granulomatous disease (CGD) were tested for their ability to metabolize arachidonic acid to lipoxygenase products including 5(S),12(R)-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid ...of ...
6
Screening Test for the Diagnosis of Chronic Granulomatous Disease
... A normal test is indicated both by the ap- pearance within 15 to 25 minutes of light blue to dark purple granules (clumps of phagocytes containing latex particles and reduced NBT). and b[r] ...
5
Topics in Chronic Granulomatous Disease
... (eg, language and academic skills).7’2 To address prob- lems in prediction, child development specialists and the American Academy of Pediatrics recommend repeating measurements through [r] ...
5
Chronic Granulomatous Disease in a Child With Klinefelter's Syndrome
... been associated with this syndrome. Several inves- tigators have observed an increased number of in- fections with this syndrome, especially of the res- pinatony tract.58 In one review o[r] ...
5
LIVER SCANS IN CHRONIC GRANULOMATOUS DISEASE OF CHILDHOOD
... Anterior Tc-99m sulfur colloid liver-spleen scan reveals a large liver with ragged “motheaten” pattern interpreted as a diffuse, infil- trative disease, such as ly-mphoma.. At biopsy, th[r] ...
12
Molecular clustering of genes related to the atopic syndrome: Towards a more tailored approach and personalized medicine?
... (FOXP3), chronic granulomatous disease (CGD; CYBA, CYBB, NCF1, NCF2 and NCF4), and phospholipase C gamma 2 (PLCG2) gene associated antibody deficiency and immune dysregulation (PLAID; PLCG2), ...
10
Reversible Neutrophil Defect in Ataxia Telangiectasia
... usual in ataxia telangiectasia1’3 but prominent in patients with chronic granulomatous disease. (CGD) where the NBT reduction test is al-[r] ...
6