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Chronic inflammatory pain

Peripheral calcium permeable AMPA receptors regulate chronic inflammatory pain in mice

Peripheral calcium permeable AMPA receptors regulate chronic inflammatory pain in mice

... peripheral, pain-sensing neurons (nociceptors), while preserving expression of these subunits in the central nervous ...of chronic inflammatory pain and ...alleviated inflammatory ...

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A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain

A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain

... of chronic inflammatory pain was then evaluated using thermal and mechanical hypersensitivity evoked by intrapla- ntar injection of ...reducing pain-related molecular ...

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Original Article Involvement of P2X7 receptors and downstream ERK pathways in chronic inflammatory pain

Original Article Involvement of P2X7 receptors and downstream ERK pathways in chronic inflammatory pain

... induced chronic inflammatory pain in mice, the current study used a variety of methods, including behavioral evalu- ation, Western blotting, Rt-PCR, immunohistochemistry, and ...alleviated ...

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Pain aversion and anxiety-like behavior occur at different times during the course of chronic inflammatory pain in rats

Pain aversion and anxiety-like behavior occur at different times during the course of chronic inflammatory pain in rats

... persistent pain in animals by monitoring the affective state behaviors using intraplan- tar CFA ...that chronic inflammatory pain leads to the development of anxiety-like behaviors at 3 or 4 ...

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Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation

Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation

... Little is known about the mechanisms upstream the nucleotide release from human fibroblasts despite the im- portance of connective tissue ATP signaling in the patho- genesis of acute and chronic ...

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ANTI-NOCICEPTIVE ACTIVITIES AND TOXICOLOGICAL PROFILE OF AQUEOUS EXTRACT OF LEAVES OF HIBISCUS ASPER

ANTI-NOCICEPTIVE ACTIVITIES AND TOXICOLOGICAL PROFILE OF AQUEOUS EXTRACT OF LEAVES OF HIBISCUS ASPER

... sub- chronic toxicity, no case of death was recorded and no modification of behavioral ...on pain induced by acetic acid was significant at doses of 125, 250 and 500 mg/kg with maximum inhibition of ...of ...

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Nonsteroidal anti-inflammatory drugs in chronic pain: implications of new data for clinical practice

Nonsteroidal anti-inflammatory drugs in chronic pain: implications of new data for clinical practice

... high compared to those used for chronic pain management (eg, in RA or OA). Another study with a similar indication (prevention of colorectal adenomatous polyps) failed to find any significant difference in ...

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Assessment and Management of Chronic Musculoskeletal Pain Syndrome in Children: A Review

Assessment and Management of Chronic Musculoskeletal Pain Syndrome in Children: A Review

... children. Pain, in particular chronic pain syndrome is currently conceptualized within a biopsychosocial ...of pain is influenced by physical factors ...MSK pain results in a large ...

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Mediation analysis of relationships between chronic inflammation and quality of life in older adults

Mediation analysis of relationships between chronic inflammation and quality of life in older adults

... the pain and disability variables also illuminate relevant deficiencies of the sick role con- cept as they relate to persistent ...from inflammatory disease, such as chronic pain, may cause ...

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Tuberculous monoarthritis of the wrist in a patient with systemic lupus erythematosus: a case report

Tuberculous monoarthritis of the wrist in a patient with systemic lupus erythematosus: a case report

... In conclusion, tuberculous arthritis should be consid- ered in the differential diagnosis in patients with chronic arthritis presenting with worsening symptoms. The onset and progression could be insidious with ...

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A classification of chronic pain for ICD-11.

A classification of chronic pain for ICD-11.

... mechanisms) within the past 5 years from Berlin Chemie, Astra Zeneca, Bayer, Heel (research grant). J. Scholz has received speaker fees from Convergence, GlaxoSmithKline, Pfizer, St Jude Medical, and Zalicus. He has ...

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Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique

Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique

... Abstract: Chronic musculoskeletal pain conditions are multifaceted, and approximately 20% of the adult population lives with severe chronic pain, with a higher prevalence in women and in lower ...

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Thesis

Thesis

... and pain, researchers discovered a broader relationship between that of cognitions and perceptions of one’s body (Chapman, ...in pain, this understanding actually arises from a number of independent factors ...

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Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain

... in DRG cells from animals with paw inflammation and CTX treatment. The number of μ-receptors did not differ significantly between untreated (set at 100%) and s.c. morphine–pretreated animals (t test, P > 0.05). (F) ...

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Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy

Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy

... Our study had some limitations. First, biopsy samples from healthy control dogs were not available, and we cannot accurately determine normal lymphatic width in the propria mucosa of the intestine. Further studies of the ...

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Effectiveness of anodal transcranial direct current stimulation in patients with chronic low back pain: Design, method and protocol for a randomised controlled trial

Effectiveness of anodal transcranial direct current stimulation in patients with chronic low back pain: Design, method and protocol for a randomised controlled trial

... J. Pain, accepted), only 8 studies have investigated tDCS for chronic pain reduction ...J. Pain, accepted) according to the GRADE system ...parameters pain intensity (VAS) and ...

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Anti-Nociceptive Effect of Safranal, a Constituent of Crocus Sativus (Saffron), in Mice

Anti-Nociceptive Effect of Safranal, a Constituent of Crocus Sativus (Saffron), in Mice

... Figure 3- Effect of a subcutaneous injection of naloxone on the antinociceptive effect of intraperitoneally administered of the morphine (i.p.) on pain threshold of mice in the hot-plate test. Each point ...

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Surgery   Current Clinical Strategies (2006 Edition) pdf

Surgery Current Clinical Strategies (2006 Edition) pdf

... A. Colon and rectal tumors account for 5% to 10% of all hospitalizations for lower gastrointestinal bleeding. Visible bleeding from a benign colonic or rectal polyp is distinctly unusual. Major or massive hemorrhage ...

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Hyperbaric oxygen relieves neuropathic pain through AKT/TSC2/mTOR pathway activity to induce autophagy

<p>Hyperbaric oxygen relieves neuropathic pain through AKT/TSC2/mTOR pathway activity to induce autophagy</p>

... neuropathic pain by inhibiting mTOR to induce autophagy in SNL neuropathic pain ...neuropathic pain via modulating AKT/TSC2/mTOR ...Neuropathic pain was induced following SNL ...

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The Antinociceptive Effects of Rosuvastatin in Chronic Constriction Injury Model of Male Rats

The Antinociceptive Effects of Rosuvastatin in Chronic Constriction Injury Model of Male Rats

... neuropathic pain due to chronic constriction ...the inflammatory factors play a key ...the inflammatory factors with its ben- eficial effects on neuropathic ...the inflammatory ...

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