Cigarette smoke
Immune-regulating effects of exercise on cigarette smoke-induced inflammation
... of cigarette smoke on the permeability and IL-1b and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pul- monary ...
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Cigarette smoke–induced reduction of C1q promotes emphysema
... from smoke-exposed but C1q-treated mice (Fig- ure 8, A and ...that cigarette smoke reduces the expression of Pparg, a critical antiinflamma- tory transcription factor, in lung APCs ...
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Cigarette smoke differentially modulates dendritic cell maturation and function in time
... that cigarette smoke has differential ef- fects on DC’s in ...of cigarette smoking in human air- ways, but it is tempting to speculate that the observed effects may contribute to the vulnerability of ...
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Original Article A simplified device for exposing rats to cigarette smoke
... to cigarette smoke, the total WBC count in the BALF of these ani- mals increased with numbers of cigarettes used, and macrophages comprised the pre- dominant inflammatory cell ...was smoke ...
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Mouse Protocadherin 1 gene expression is regulated by cigarette smoke exposure in vivo
... to cigarette smoke and is expressed in bronchial epithelial ...short-term cigarette smoke exposure models characterized by airway inflammation and hyperresponsiveness and chronic ...
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Cigarette smoke exposure facilitates allergic sensitization in mice
... which recirculate via the bloodstream towards the lungs where we could measure them (BALF and lung tissue). Not only increases in DC and T-cells, but also a substan- tial amount of eosinophils and to a far lesser extent ...
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Cigarette smoke alters the ability of human dendritic cells to promote anti-Streptococcus pneumoniae Th17 response
... by cigarette smoke inhibits LPS-induced DC maturation [13] and production of interleukin-12 (IL-12) and IL-23 which are involved in Th1 and Th17 T-cell differentiation, respectively ...on cigarette ...
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Regulation of Nitric Oxide by Cigarette Smoke in Airway Cells
... by cigarette smoking in asthmatic airways, which leads to more L- arginine consumption ...that cigarette smoke extract inhibits NOS activity in a healthy male rabbit model ...
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Effects of exposure to cigarette smoke prior to pregnancy in diabetic rats
... diabetes/cigarette smoke association, regardless of the exposure ...to cigarette smoke prior to and into pregnancy ...The cigarette contains high levels of toxic substances that may ...
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The role of environmental exposure to non-cigarette smoke in lung disease
... biomass smoke induced inflammation- mediated lung injury [116, ...dung smoke upregulated the expres- sion of PAFR on human bronchial epithelial cells, we believe that the induction of microbial adhesion ...
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The role of cigarette smoke-induced epigenetic alterations in inflammation
... CS: cigarette smoke; DNMT: DNA methyl transferase; ERK: extracel- lular signal-regulated kinase; EZH2: enhancer of zeste homolog 2; HAT: histone acetyltransferase; HDAC: histone deacetylase; HMT: histone ...
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Effects of cigarette smoke on salivary protein tyrosine nitration
... arette smoke (cS) is presently known as the main cause of cancer, chronic bronchitis, emphysema, car- diovascular disease, and a leading cause of death worldwide ...[3]. cigarette smoke is also a ...
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Regional heterogeneity in response of airway epithelial cells to cigarette smoke
... Background: Cigarette smoke (CS) exposure causes an abnormal inflammatory response, which can result in chronic obstructive pulmonary disease (COPD). Previous studies show that this disorder predominantly ...
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CSEO – the Cigarette Smoke Exposure Ontology
... exposure. Most exposure experiments follow a similar routine summarized as follows: the design, factors, and protocols of an experiment must be defined before conducting the experiment. This is often the case for ...
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CD147 increases mucus secretion induced by cigarette smoke in COPD
... Forty-two subjects were recruited for this study, includ- ing 14 non-smokers without COPD, 14 smokers with- out COPD, and 14 smokers with COPD. The inclusion criteria were as follows: All subjects underwent pul- monary ...
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Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model
... of cigarette smoke-induced ...blocked cigarette smoke-induced MMP-8 and -9 protein syn- thesis, but also significantly stimulated TIMP-1 and -4 protein synthesis in the presence of ...
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Lung glutathione adaptive responses to cigarette smoke exposure
... The lung is unique since it is exposed to high ambient oxygen levels and a constantly changing atmospheric environment. The lung is exposed on a daily basis to a wide range of oxidants ranging from ozone, smog, diesel ...
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Cigarette smoke inhibition of ion transport in canine tracheal epithelium
... to cigarette smoke decreased the short circuit current and transepithelial ...of cigarette smoke was reversible, was not observed upon exposure of the submucosal surface to smoke, and ...
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Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells
... in cigarette smoke involve a combination of direct and indirect effects on cells, but principally center around an increase in airway inflam- mation as a result of cigarette ...
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Modelling the asthma phenotype: impact of cigarette smoke exposure
... Scientific, UK). Rats were exposed to room air or CS for 1 h, twice a day (4 h apart) on day 21, 22, 23, 24, 25, 26, and 27. On day 28 the rats were exposed to air/smoke in the morning and in the afternoon the ...
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