Classical Hodgkin Lymphoma
PiwiRNA-651 as marker of treatment response and survival in classical Hodgkin lymphoma
... PiwiRNAs, small non-coding RNAs processed by Piwi proteins, are involved in maintaining genome stability in germline cells. Recently, piwiRNA expression has been identified in some tumors. We have examined the potential ...
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Predicting treatment outcome in classical Hodgkin lymphoma: genomic advances
... cHL, classical Hodgkin lymphoma; DSS, disease-specific survival; EBV, Epstein-Barr virus; FDG, fluorodeoxyglucose; FFS, Figure ...of classical Hodgkin ...B-cell lymphoma 2; ...
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Original Article Classical Hodgkin lymphoma with necrotic granuloma-like morphological features
... Granuloma-like Hodgkin Lymphoma (NGHL), which is a classical Hodgkin lymphoma (CHL) with uncommon morphologic features that are rich of tumor cells and has particular necrotic ...
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Chronic Epstein Barr virus infection leading to classical Hodgkin lymphoma
... Our case illustrates one of the different clinical features in the spectrum of EBV infection. Age-related EBV- associated lymphoproliferative disorders represent a well described complication of EBV infection, typically ...
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Rituximab, etoposide, methylprednisolone, high dose cytarabine, and cisplatin in the treatment of secondary hemophagocytic lymphohistiocytosis with classical Hodgkin lymphoma: a case report and review of the literature
... With still no clear identifying etiology for secondary HLH, underlying malignancy was suspected and a positron emission tomography (PET) scan was performed. This re- vealed an enlarged right cervical lymph node measuring ...
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HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells
... In classical Hodgkin lymphoma (cHL) chemotherapeutic regimens are associated with stagnant rates of secondary malignancies requiring the development of new therapeutic ...
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Infused autograft lymphocyte to monocyte ratio predicts survival in classical Hodgkin lymphoma
... B-cell lymphoma after autologous peripheral hematopoietic stem cell transplantation ...in classical Hodgkin ...with classical Hodgkin lymphoma who underwent APHSCT were ...with ...
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CD163 versus CD68 in tumor associated macrophages of classical hodgkin lymphoma
... Classical Hodgkin lymphoma (CHL) is a B-cell lymphoproliferative disorder with a relatively good prognosis. A small but significant percentage of patients, however, will respond poorly to therapy. A ...
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Meta-analysis of the prognostic and clinical value of tumor-associated macrophages in adult classical Hodgkin lymphoma
... We performed a systematic electronic search in PubMed, Embase, and Google scholar for articles pub- lished before January 31, 2016. We identified studies by using Medical Subject Heading (MeSH) terms and corresponding ...
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Advances in CD30- and PD-1-targeted therapies for classical Hodgkin lymphoma
... large-cell lymphoma; ALL: Acute lymphoblastic leukemia; Allo-SCT: Allogeneic stem cell transplantation; ASCT: Autologous stem cell transplantation; ASH: American Society of Hematology; AVD: Adriamycin, ...
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<p>The Evolving Role of Brentuximab Vedotin in Classical Hodgkin Lymphoma</p>
... A greater understanding of the pathophysiology of classi- cal Hodgkin lymphoma has enabled researchers to identify and develop effective targeted therapies that have improved outcomes for patients. These ...
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Phase 2 study of everolimus for relapsed or refractory classical Hodgkin lymphoma
... In summary, this phase 2 trial demonstrated that everoli- mus monotherapy can produce a favorable ORR and median PFS in heavily pretreated patients with relapsed or refractory classical HL. The overall safety ...
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Original Article Expression of Sirt1 and FoxP3 in classical Hodgkin lymphoma and tumor infiltrating lymphocytes: Implications for immune dysregulation, prognosis and potential therapeutic targeting
... against Hodgkin lymphoma de- rived cell lines, inducing cell death as well as inhibiting the Sirt1 pathway ...refractory lymphoma patients with an additional 57% reportedly achieving stable disease ...
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PD-1 blockade induces remissions in relapsed classical Hodgkin lymphoma following allogeneic hematopoietic stem cell transplantation
... However, there is concern that enhancing the GVT ef- fect through administration of CBT might also induce or exacerbate graft-versus-host disease (GVHD). Indeed, ipilimumab treatment was discontinued in 4 of 29 pa- ...
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<p>Abdominal Lymphocyte-Depleted Hodgkin Lymphoma: A Rare Presentation</p>
... This case represents a rare entity of lymphocyte-depleted classical Hodgkin lymphoma. The literature suggest that the overall incidence of LDcHL is decreasing over time. The reasons for this slow ...
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Rapidly Progressing Refractory Hodgkin Lymphoma: A Case Report and a Possible Explanation
... subtype classical Hodgkin lym- phoma ...subtype classical Hodgkin lymphoma patients at baseline may be candidates for frontline brentuximab vedotin administration, if verified in large ...
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CD30: receptor, marker, target
... in classical Hodgkin lymphoma the malignant cells and background cells are engaged in cross ...of Hodgkin lymphoma, mixed cellularity, in particular, EBV infection of the malignant ...
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Review Article Pitfalls in diagnostic hematopathology – Part II
... between classical Hodgkin lymphoma (cHL) and related diseases such as primary mediastinal large B-cell lymphoma (PMLBL), nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL), ...
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Case report: a unique pediatric case of a primary CD8 expressing ALK-1 positive anaplastic large cell lymphoma of skeletal muscle
... from classical Hodgkin lymphoma (cHL), CD30+ non-Hodgkin B cell lympho- mas and very rare ALK-1 positive (and eventually CD30- negative) large B cell ...
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An atypical presentation of sporadic ovarian Burkitt’s lymphoma: case report and review of the literature
... (WHO) classification recognizes three clinical subtypes of BL: African or endemic, sporadic and immunodefi- ciency associated. Burkitt’s lymphoma of the ovaries can be primary or more frequently secondary to a ...
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