Classification of airflow limitation severity in COPD based on
COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma–COPD overlap syndrome
... with COPD, 51 patients with ACOS, and 44 patients with chronic cough, treated at Saitama Cardiovascular and Respiratory Center from January 23, 2015 to August 31, 2015, were enrolled in this ...16 COPD was ...
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Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients
... severe airflow limitation had a significant decrease in the RA of Treponema and a progressive increase in the RA of Pseudomonas ...that severity-related changes in the respiratory microbiome are ...
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Severity of Airflow Obstruction in Chronic Obstructive Pulmonary Disease (COPD): Proposal for a New Classification
... of severity based on the FEV 1 /FVC ratio with cut-points dividing the population into four similar sized strata to those created by the GOLD criteria using FEV 1 ...-based classification in ...
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Diagnosis of COPD and clinical course in patients with unrecognized airflow limitation
... Recent studies by Mannino and the MESA study group have begun to define a “restricted” lung pathology based on FVC , 80% of predicted and no spirometric evidence of AFL. 19,41 These studies found increased ...
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<p>Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation</p>
... the severity of air fl ow obstruction when considering what prophylactic therapy to prescribe as erdosteine did not reduce the number of moderate or severe events reported by our ...early COPD leading to ...
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Comparison of pulmonary function in patients with COPD, asthma-COPD overlap syndrome, and asthma with airflow limitation
... was based on a retrospective evaluation of asthma-related ...between COPD and ACOS in some patients, because asthma-related symptoms may not only be specific for asthma but may also characterize ...disease ...
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Comorbidities according to airflow limitation severity: data from comprehensive health examination in Japan
... between COPD and diabetes is not entirely understood, although thought to involve systemic inflammation with central roles for IL-6 and TNF-α ...in COPD pa- tients who are at the earlier stages of ...
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The Relationship between COPD Assessment Test (CAT) Scores and Severity of Airflow Obstruction in Stable COPD Patients
... of COPD was established based on a medical history of smoking, current symptoms of cough, dyspnea or sputum production and available standard pulmonary function test which was performed by a spirometer ...
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Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity
... studies based on micro-CT imaging and histology showed a decrease in the number and the mean diameter of remodeled bronchioles in COPD ...and COPD status or severity, probably be- cause of a ...
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Neutrophil extracellular trap (NET) formation characterises stable and exacerbated COPD and correlates with airflow limitation
... of COPD-associated NETosis The diagnostic and therapeutic relevance of our results is further strengthened by the finding that COPD related NETosis clearly correlates with the impairment of lung function, ...
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Relationship of airflow limitation severity with work productivity reduction and sick leave in a Japanese working population
... al COPD is a debilitating disease affecting the daily lives of ...of COPD. 8 Increasing severity of COPD is associated with decreasing physical ...with COPD, data on its impact on ...
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Correlation of serum uric acid with severity of airflow limitation in the patients of chronic obstructive pulmonary disease
... and intestine. Exogenous purines also represent an important source of uric acid, and approximately 50% of RNA purines and 25% of DNA purines are absorbed in the intestine and subsequently excreted in urine. 4 Tissue ...
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Airflow obstruction: is it asthma or is it COPD?
... asthma, COPD, chronic bronchitis, or emphysema is not fully reli- able, particularly in family practice, where the diagnostic process is primarily based on symptoms and signs presented by the ...
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<p>Association between airflow limitation severity and reduced bone mineral density in Japanese men</p>
... with COPD is not ...in COPD-associated osteoporo- sis, and COPD patients with lower BMD have been shown to exhibit higher levels of ...in COPD-associated osteoporosis and its contribution to ...
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3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation
... 10,12 COPD affects the tracheobronchial angles. Based on the observations showing significant cor- relations between the tracheobronchial angles and the LV in this study, it is relatively easy to predict ...
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Airflow limitation or static hyperinflation: which is more closely related to dyspnea with activities of daily living in patients with COPD?
... is based just on correlation analysis, which is not the best way to detect the cause of a ...between airflow limitation and static hyperinflation on clinical dyspnea, over half of the contributory ...
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Comorbidities and COPD severity in a clinic-based cohort
... GOLD classification are based on dyspnea and exac- erbations but not on ...for COPD regarding lung function [17]. In addition, man- agement of COPD differed according to the comorbidi- ties ...
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Efficacy and safety of twice-daily glycopyrrolate in patients with stable, symptomatic COPD with moderate-to-severe airflow limitation: the GEM1 study
... study based on the findings of a dose-ranging study in which glycopyrrolate ...with COPD 10 and was considered a reasonable dose for a twice-daily regimen fol- lowing regulatory interactions for advancement ...
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Exome wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12
... β(𝑀𝐴𝐹 𝑗 ; 1, 25)). We filtered gene-based results to only include genes with at least two SNPs with a MAF<5%, and with a cumulative MAF>0.05%. To further evaluate notable gene based signals, we utilised a ...
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Exome wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12
... and COPD risk in two regions not previously implicated in COPD or lung ...with COPD with a very rare SNP in SERPINA12 ...of COPD cases and controls is ...to severity of air fl ow ...
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