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Clear cell renal cell carcinoma

A four-gene signature predicts survival in clear-cell renal-cell carcinoma

A four-gene signature predicts survival in clear-cell renal-cell carcinoma

... Clear-cell renal-cell carcinoma (ccRCC) is the most common pathological subtype of renal cell carcinoma (RCC), accounting for about 80% of ...

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Ovarian metastasis of clear cell renal cell carcinoma: A case report

Ovarian metastasis of clear cell renal cell carcinoma: A case report

... for clear cell renal cell carcinoma (RCC) occurring 21 years ago; she currently presented with a bilateral ovarian ...was clear cell carci- ...be clear cell ...

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Clinical impact of targeted therapies in patients with metastatic clear-cell renal cell carcinoma

Clinical impact of targeted therapies in patients with metastatic clear-cell renal cell carcinoma

... Introduction: The aim of this retrospective clinical study was to assess, in the context of the recent evolution of systemic therapies, the potential effect of targeted therapies on overall survival (OS) of patients with ...

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Original Article The effects of LOXL2 in clear cell renal cell carcinoma: a

Original Article The effects of LOXL2 in clear cell renal cell carcinoma: a

... in clear cell renal cell carcinoma (ccRCC) remain limited, and their results are ...ccRCC cell lines (786-O, A-498, ACHN, and Caki-1) and the normal renal cell line ...

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Insulin Receptor Expression in Clear Cell Renal Cell Carcinoma and Its Relation to Prognosis

Insulin Receptor Expression in Clear Cell Renal Cell Carcinoma and Its Relation to Prognosis

... in clear cell renal cell carcinoma (CCRCC) and non-tumor ...of carcinoma and adjacent non-tumor was analyzed with ...normal renal parenchymal ...

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GFOD1 and peejar are promising markers for clear-cell renal cell carcinoma disease progression

GFOD1 and peejar are promising markers for clear-cell renal cell carcinoma disease progression

... Clear cell renal cell carcinoma (ccRCC) is a common genitourinary malignancy. The molecular pathogenesis of ccRCC remains unclear and biomarkers for daily practice were still limited. ...

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Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI

... uninvolved renal parenchyma (URP), a finding consistent with the literature (29–31) (Figure ...4. Clear cell renal cell carcinoma (ccRCC) exhibits widespread metabolic ...

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Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

Towards a Personalized Cancer Gene Therapy: A Case of Clear Cell Renal Cell Carcinoma

... the cell hierarchy and test our procedure on a surgically removed metastatic clear cell renal cell ...cancer cell commanders are in low positions in normal ...cancer cell ...

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Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma

Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma

... Recently, Vargiu et al. compiled a database of 3,173 intact, full- length hERV sequences and developed a comprehensive method for classifying these sequences into 11 superfamilies (Supplemen- tal Table 1; supplemental ...

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Upregulation of Rarb, Rarg, and Rorc Genes in Clear Cell Renal Cell Carcinoma

Upregulation of Rarb, Rarg, and Rorc Genes in Clear Cell Renal Cell Carcinoma

... Thus, for the first time it was performed a quantitative expression analysis of genes encoding nuclear receptors of retinoids in clear cell renal cell carcinoma in humans. The study ...

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Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma

Targeting HIF2α Translation with Tempol in VHL-Deficient Clear Cell Renal Cell Carcinoma

... cancer, clear cell renal cell carcinoma ...in clear cell kidney cancer have suggested that HIF2α, but not HIF1α, is the critical oncoprotein in the VHL ...different ...

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Metabolic features of clear cell renal cell carcinoma: mechanisms and clinical implications

Metabolic features of clear cell renal cell carcinoma: mechanisms and clinical implications

... Central to the malignant behaviour that endows cancer cells with growth advantage is their unique metabolism. Cancer cells can process nutrient molecules differently from normal cells and use it to overcome stress ...

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SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis

SENP1 promotes proliferation of clear cell renal cell carcinoma through activation of glycolysis

... inherited renal cancer syndromes caused by germline mutations identified to date exhibit disorders in oxygen, iron, nutrient, or energy sensing, RCC has been viewed as a metabolic disease ...that clear ...

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CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma

CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma

... Renal cell carcinoma (RCC) is the most prevalent malig- nancy of the kidney, and it accounts for ...[1]. Clear cell renal cell carcinoma (ccRCC) represents the ...

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Extracellular miR-224 as a prognostic marker for clear cell renal cell carcinoma.

Extracellular miR-224 as a prognostic marker for clear cell renal cell carcinoma.

... in clear cell renal cell carcinoma ...in renal cell ...or cell culture media, we examined exosome morphology using transmission electron microscope ...metastatic ...

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AHNAK2 is a Novel Prognostic Marker and Oncogenic Protein for Clear Cell Renal Cell Carcinoma

AHNAK2 is a Novel Prognostic Marker and Oncogenic Protein for Clear Cell Renal Cell Carcinoma

... in clear cell renal cell carcinoma ...cancer cell proliferation, colony formation and migration in vitro and tumorigenic ability in ...the cell oncologic-metabolism by ...

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NDRG2 suppresses the proliferation of clear cell renal cell carcinoma cell A-498

NDRG2 suppresses the proliferation of clear cell renal cell carcinoma cell A-498

... Renal cell carcinoma (RCC) accounts for 3% of all malignant tumors and 90% of neoplasms arising from the ...States, renal cancer is the 7th leading malignant condition among men and the 12th ...

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Genetic mutations associated with metastatic clear cell renal cell carcinoma

Genetic mutations associated with metastatic clear cell renal cell carcinoma

... Metastasis is the major cause of death among cancer patients, yet early detection and intervention of metastasis could significantly improve their clinical outcomes. We have sequenced and analyzed RNA (Expression) and ...

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The epigenetic landscape of clear-cell renal cell carcinoma

The epigenetic landscape of clear-cell renal cell carcinoma

... Clear cell renal cell carcinoma (ccRCC) is the most common subtype of all kidney tumors. During the last few years, epigenetics has emerged as an important mechanism in ccRCC ...

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Changes in the expression and subcellular distribution of galectin-3 in clear cell renal cell carcinoma

Changes in the expression and subcellular distribution of galectin-3 in clear cell renal cell carcinoma

... of clear cell renal cell carcinoma (RCC-FG1) (Cell Lines Service, Germany) were cultivated in McCoy’s 5a medium/10% FCS (PAA, Pasching, ...

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