clinical studies/trials
Repurposing metformin for cancer treatment: current clinical studies
... Eleven trials (20% of all ongoing trials using metformin as an anti-cancer agent; Tables 1-3) are focused on evaluating metformin as a treatment for breast ...two trials are using metformin as ...
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Systematic review of methodology used in clinical studies evaluating the benefits of proton beam therapy Clinical and Translational Radiation Oncology
... practice-changing trials [66], there is an obligation to answer the question as to whether the dosimetric benefits of PBT translate into meaningful clinical benefits ...opportunity, trials evaluating ...
38
Robotic right colectomy for hemorrhagic right colon cancer: a case report and review of the literature of minimally invasive urgent colectomy
... of clinical studies focusing on minim- ally invasive colectomy performed in emergency or urgent setting in adult patients with colon carcinoma was under- ...of studies eligible for the review, the ...
7
Current and Future Imaging Methods for Evaluating Response to Immunotherapy in Neuro-Oncology
... concurrent clinical trials investigating various immunotherapy strategies in ...These studies have shown ongoing challenges to monitor therapeutic efficacy due to variations in response patterns ...
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Comparisons of therapeutic efficacy and safety of ipilimumab plus GM-CSF versus ipilimumab alone in patients with cancer: a meta-analysis of outcomes
... Recent clinical studies have shown that initial therapy with combined cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) blockade and granulocyte-macrophage colony- stimulating factor (GM-CSF)-based ...
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When participants get involved: reconsidering patient and public involvement in clinical trials at the MRC Clinical Trials Unit at UCL
... all clinical studies that are being led by the ...in clinical trials, cohort studies or systematic reviews, and two of the staff members had been directly involved in the three ...
8
Tegenero clinical trials disaster
... pre-clinical studies due to differences in target molecules and physiology of immune system in animal models; for example it has been shown that blockade of the interaction of CD40 with its ligand (CD40L), ...
7
New regulation for clinical stem cell research in China : expected impact and challenges for implementation
... all, clinical investigators may not charge money for patients taking part in clinical studies, and hospitals are not allowed to advertise stem cell trials as ...
6
Statin use and the risk of <em>Clostridium difficile</em> infection: a systematic review with meta-analysis
... individual studies included in our meta-analysis varied in several ways, including study design, patient population, study setting (inpatient vs outpatient vs ICU), NAP1 (North American pulsed-field gel ...
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Thymectomy in nonthymomatous myasthenia gravis - systematic review and meta-analysis
... other studies were case series or case-control, therefore subject to the effect of ...case-control studies matched the pa- tients by age, gender, and other confounders, thus redu- cing the risk of bias [17, ...
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Practice effects in a longitudinal, multi center Alzheimer’s disease prevention clinical trial
... longitudinal studies investi- gating reliable change indices (RCI), we view this as an issue that is related to but separate from ...longitudinal studies are typically not used to detect subtle declines per ...
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Click here to download PDF version of the article !
... aforesaid clinical trials as well [4,10,31,33]. Therefore, the five studies discussed above have low risk of ...more trials are required to explore long term antibacterial efficacy of triphala ...
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Automating and estimating glomerular filtration rate for dosing medications and staging chronic kidney disease
... Objective: The purpose of this paper is to serve as a review for primary care providers on the bedside methods for estimating glomerular filtration rate (GFR) for dosing and chronic kidney disease (CKD) staging and to ...
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Characteristics of clinical trial websites: information distribution between ClinicalTrials gov and 13 primary registries in the WHO registry network
... for clinical cancer trials using data imported from ...of clinical trials from the ...of clinical trial search results, patients and the public can easily understand the contents and ...
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Clinical trials update: recent and ongoing studies in anticoagulation for atrial fibrillation
... blinded trials are not always possible, due to cost consider- ations and complexity in ...double-blinded trials may introduce other sources of bias in their own right, such as biases in patient selection by ...
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Core outcome sets for clinical trials and observational studies in vulvovaginal disease
... randomised studies are heterogeneous, of poor methodological quality and difficult to combine in metaanalysis, meaning that they cannot be utilised to inform evidence based ...
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Evidence-based medicine databases: An overview
... research studies, assisting others in carrying out reviews, and providing training and guidance in systematic ...research studies and ...(DoPHER), Trials Register of Promoting Health Interventions ...
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New perspectives in human stem cell therapeutic research
... involved. Clinical trials are underway and there is optimism that benefits will be clearly demonstrated ...of clinical benefit across trials, an issue that has been a constant dif- ficulty for ...
5
Schizophrenia trials in China: a survey
... Previous studies have suggested that literature from less well known sources is not accessible to those searching only mainstream databases ...relevant studies can lead to less precise results than would ...
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Use of cognitive enhancers for mild cognitive impairment: protocol for a systematic review and network meta-analysis
... The electronic database search will be supplemented by searching for difficult to locate or unpublished mater- ial (that is, grey literature) using methods (Tricco, un- published paper submitted to BMC SRs). Briefly, we ...
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