Coding RNA
The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology
... Among all successful efforts in applying semantic tech- nologies in the biomedical domain, the Open Biological and Biomedical Ontologies (OBO) Library [8] is of spe- cial importance in that it has served as an umbrella ...
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CRNDE: an oncogenic long non-coding RNA in cancers
... CRNDE is located at an atypical locus—hCG_1815491 on chromosome 16—and is activated early in colorec- tal cancer (CRC) [16]. CRNDE is classified as a long non-coding RNA because it is longer than 200 ...
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Expression and clinical significance of long non coding RNA HNF1A AS1 in human gastric cancer
... antisense RNA (HOTAIR), a long intergenic non- coding RNA, is associated with the grade of endometrial carcinoma (EC), metastasis, depth of myometrial invasion, and poorer overall survival ...
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The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications
... are RNA molecules of any size that are transcribed from DNA, but do not undergo translation in to a stable ...interfering RNA (siRNA), piwi-interacting RNA (piRNA), and long non-coding ...
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Effects of miRNA-143 and the non-coding RNA MALAT1 on the pathogenesis and metastasis of HeLa cells.
... non-coding RNA, it is expressed in various tumors and tissues, and may affect proliferation, apoptosis, invasion, metastasis, and drug resistance of tumors (Gutschner et ...
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Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein
... an RNA binding protein complex from a heterogeneous cellular homogenate in ...small RNA or even coding RNA can be measured with real-time PCR or be identified by RNA sequencing ...bind ...
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Enhanced expression of long non coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
... Methods: One hundred thirty-one GAC tissues and matched adjacent normal tissues (ANTs) were collected from patients who undergone surgery. Differences in of NEAT1 expression were examined via quantitative reverse ...
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Comprehensive landscape of subtype-specific coding and non- coding RNA transcripts in breast cancer
... including coding, long non- coding RNA and microRNA ...all coding and non-coding RNAs is estimated from RNA-sequence data of 1168 breast samples obtained from The Cancer Genome ...
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UpSETing chromatin during non-coding RNA production
... intergenic RNA; HOTTIP: HOXA distal tip transcript antisense RNA; HOX: Homeobox; Hst: Homolog of SIR2; IME: Inducer of meiosis; Isw: Imitation Switch; K: Lysine; KDAC: Lysine deacetylases; KDM: Lysine ...
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Original Article Long non-coding RNA ANRIL promotes tumorigenesis in glioma via MAPK signaling pathways
... non-coding RNA called long non-coding RNA (lncRNA >200 bp in length), which have been proven to regulate many biological processes from nuclear organi- zation to epigenetic modification of ...
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<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... non-coding RNA; SNHG5, small nucleolar RNA host gene 5; ncRNA, non-coding RNA; miRNA, microRNA; siRNA, small interfering RNA; tRNA, transfer RNA; rRNA, ribosomal ...
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<p>Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer</p>
... on HER-2 overexpressed subtype, such as Trastuzumab and Pertuzumab, 2,3 while immunotherapies are aimed at triple-negative breast cancer (TNBC) due to its higher immunogenicity. 4,5 Quite a number of prognostic markets ...
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Editorial focus: entering into the non-coding RNA era
... Recent developments in high-throughput genotyping technologies have revealed the existence of several new classes of RNA that do not encode proteins but serve other cellular roles. To date, these non-coding ...
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Long non-coding RNA: a new player in cancer
... Another regulation mechanism of lncRNAs is to serve as scaffolds. Studies demonstrated that lncRNA KCNQ1OT1 could bind both G9a and PRC2, and lncRNA HOTAIR could interact with PRC2 and LSD1, revealing these lncRNAs can ...
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Long non-coding RNA ENST00000457645 reverses cisplatin resistance in CP70 ovarian cancer cells.
... Total RNA extracted from A2780 and CP70 cells was labeled with a fluorochrome using the Quick Amp Labeling Kit (Agilent, Santa Clara, CA, USA) according to the manufacturer ...the RNA to probes on the ...
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Clinical significance of long non-coding RNA HOTTIP in early-stage non-small-cell lung cancer
... The HOX family genes are known transcription fac- tors with a key role in embryogenesis and carcinogen- esis [10, 11]. Their expression is dysregulated in several cancers, including NSCLC [11–14]. In humans, HOX genes ...
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The standard operating procedure of the DOE-JGI Metagenome Annotation Pipeline (MAP v.4)
... non-coding RNA genes are identified using a combination of Hidden Markov Models and ab initio gene ...non- coding RNAs, tRNAs, are predicted using tRNAscan ...
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Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis
... Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma. Long noncoding RNA-LET, which is repressed by EZH2,[r] ...
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Use of RNA sequencing to evaluate rheumatic disease patients
... enhancer RNA (eRNA), a class of relatively short non-coding RNA molecules transcribed from the DNA sequence of enhan- cer regions, whose transcription is positively correlated with the mRNA levels of ...
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<p>Association Between lncRNA HULC rs7763881 Polymorphism and Gastric Cancer Risk</p>
... Purpose: Gastric cancer (GC) is one of the most common cancers in the world. Recently, several studies have suggested that single-nucleotide polymorphisms (SNPs) of long non- coding RNA (lncRNA) are ...
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