collagen molecules
Relative orientation of collagen molecules within a fibril: a homology model for homo sapiens type I collagen
... the collagen molecules aggregate as a result of the intermolecular forces, before later forming the covalent interactions via the mature enzymatic ...the collagen mole- cules will be to maximise the ...
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A Novel Biomaterial for Cartilage Repair Generated by Self Assembly: Creation of a Self Organized Articular Cartilage Like Tissue
... the collagen solution, collagen molecules started to gather around an AG + HA aggregate, followed by for- mation of collagen fibers bound ...fibrous collagen were observed over the time ...
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The fibrotic tumor stroma
... 2. Collagen cross-linking in fibrosis and ...I collagen fibrils (reprinted with permission from the Journal of Biological Chemistry, ...I collagen molecules (wavy lines) packed in a fibril in ...
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Micro differential scanning calorimetry and micro hot table method for quantifying deterioration of historical leather
... levels: molecules, fibrils and fibres ...of collagen molecules. The collagen molecule is made of three polypeptide chains, called α-chains, which form a unique triple helix structure which is ...
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Effects of isopropanol on collagen fibrils in new parchment
... lagen molecules is an effective way of measuring altera- tion to the collagen molecular ...between collagen molecules in the lateral plane of the collagen fibril (intermolecular lateral ...
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Osteogenesis imperfecta The position of substitution for glycine by cysteine in the triple helical domain of the pro alpha 1(I) chains of type I collagen determines the clinical phenotype
... I collagen molecules and additional molecules that had one or two alpha 1(I) chains that contained a cysteine residue within the triple-helical domain, a region from which cysteine normally is ...
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Tumor-associated collagen signatures: pushing tumor boundaries
... A 2016 publication features a novel in vitro arrangement where Matrigels of two different densities were interfaced. The less-dense 2-mg/ml gel contained MDA-MB-231 cells, and it was seen that these cells generated ...
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LAP (NF IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region
... transcription in both orientations and when placed in front of either a homologous or a heterologous chimeric report construct. These experiments suggest that LAP may be important in the expression of collagen in ...
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Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat
... a collagen scaffold group (collagen/En-PSCs; 18 uterine horns), an En-PSCs with low CYR61 expression loaded on a collagen scaffold group (collagen/si-CYR61 En-PSCs; 16 uterine horns), and an ...
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Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression
... non-pepsinized collagen type I was extracted from tail tendons of 2 months (adult) and 2 years old (old) rats, and prepared as already described ...old collagen solubilized at 2 mg/ml in 18 mM acetic acid ...
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Type 1 regulatory T cells specific for collagen type II as an efficient cell based therapy in arthritis
... functional collagen type II–specific type 1 regulatory T (Col-Treg) cell clones from RA patients [22], suggesting that Tr1 cell–based therapy could be a novel therapeutic strategy for treating patients with ...
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Simplified Extraction and Characterization of Acetic Acid Solubilized Type I Collagen Derived from Solea Solea Skin and Wistar Rat Tails for Biomedical and Biotechnological Applications
... of collagen, this is the reason for chosen as alternative source in the present ...tails, collagen was extracted by an adapted way using a modified method of which used by Huang et ...fibril collagen ...
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IgG glycoforms in arthritis
... cartilage. The synovial membrane which surrounds and maintains the joint space becomes intensely cellular as a result of considerable immunological hyperactivity as evidenced by large numbers of T-cells, mostly CD4, in ...
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Effect of Dimethylaminoethano and Compound Amino Acid on Periostin and Dermatopontin Expression in the Skin of D-galactose Induced Aging Model in Rats
... fibroblast collagen, proliferating type I ...I collagen to regulate the formation of collagen fibrils in connective tissue of ...excessive collagen secretion and so ...of collagen ...
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Bone Matrix Turnover And Balance In Vitro: I The effects of parathyroid hormone and thyrocalcitonin
... matrix collagen in ...matrix collagen, part is derived from new synthesis of soluble collagen occurring in vitro, and the remainder is released by cell-mediated resorptive ...
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Degradation of Extracellular Matrix Molecules in Interleukin-1 Alpha Treated Bovine Nasal Cartilage
... Since during destruction process these macromolecules come out from cartilage, identifying them or other macromolecules could be useful to understand the underlying process. There is little data about which proteins of ...
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Coexpression of the collagen binding stress protein HSP47 gene and the alpha 1(I) and alpha 1(III) collagen genes in carbon tetrachloride induced rat liver fibrosis
... 1(I) collagen and was observed only in cells lining collagen ...These collagen-positive cells were confirmed to be Ito cells by immunohistochemistry for ...
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Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats
... (50 or 100 mg/kg/d, subcutaneous) on vascular remodeling was investigated in hypoxia-induced PH model. At the end of the experiments, the indexes for pulmonary vascular remodeling and right ventricle hypertrophy were ...
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Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
... I collagen; C3M: MMP-degraded type III collagen; C3M/PRO-C3: Type III collagen degradation to formation; C4M: MMP- degraded type IV collagen; CR: Complete response; CTLA-4: Cytotoxic T ...
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Collagen and Collagen derived Fragments Are Chemotactic for Tumor Cells
... in collagen such as liver, lungs, and bone are frequently sites of tumor cell ...to collagen in ...the collagen helix caused similar ...that collagen or collagen fragments released ...
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