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Combination Antiretroviral Therapy (cART)

Efficacy and safety of abacavir containing combination antiretroviral therapy as first line treatment of HIV infected children and adolescents: a systematic review and meta analysis

Efficacy and safety of abacavir containing combination antiretroviral therapy as first line treatment of HIV infected children and adolescents: a systematic review and meta analysis

... The primary objective of this review was to assess the antiviral efficacy of abacavir-containing combination antiretroviral therapy cART regimens in comparison with cART regimens contain[r] ...

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Plasma biomarkers of clinical response during chemotherapy plus combination antiretroviral therapy (cART) in HIV+ patients with advanced Kaposi sarcoma

Plasma biomarkers of clinical response during chemotherapy plus combination antiretroviral therapy (cART) in HIV+ patients with advanced Kaposi sarcoma

... Twenty seven consecutive HIV+ patients with advanced KS stage (≥T1), according to the AIDS Clinical Trials Group (ACTG) classification [35], were considered in this study. All patients were of Caucasian ethnicity, all ...

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Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania

Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania

... prolonged cART use among HIV-infected children and suggest that suppressive NNRTI-based regimens can be associated with lower levels of systemic inflammation ...

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Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects

Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects

... ACC: Anterior cingulate cortex; cART: Combination antiretroviral therapy; CD163: Scavenger receptor, monocyte/microglia/macrophage marker; CD68: Glycoprotein, monocyte/microglia/macropha[r] ...

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Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co infected patients, Cohere in Eurocoord

Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co infected patients, Cohere in Eurocoord

... DOC 29 kb Abbreviations HCV: Hepatitis C virus; cART: combination antiretroviral therapy; Cohere: Collaboration of Observational HIV Epidemiological Research in Europe; SVR: Sustained vi[r] ...

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TGFβRI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment

TGFβRI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment

... variance; cART: Combination antiretroviral therapy; CCL2: CC chemokine family ligand 2; CD163: Cluster of differentiation 163; CMV: Cytomegalovirus; CNS: Central nervous system; CXCL10/IP-10: ...

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Phenotypic Characteristics and Function of NK Cell Subsets in cART Treated HIV 1 Infected Individuals

Phenotypic Characteristics and Function of NK Cell Subsets in cART Treated HIV 1 Infected Individuals

... We analyzed NK cell distribution and function of successfully combination antiretroviral therapy cART-treated HIV-1 infected individuals in Khon Kaen Regional Hospital, Thailand.. The re[r] ...

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Risk factors affecting the mortality of HIV-infected patients with pulmonary tuberculosis in the cART era: a retrospective cohort study in China

Risk factors affecting the mortality of HIV-infected patients with pulmonary tuberculosis in the cART era: a retrospective cohort study in China

... on combination antiretroviral therapy ...without cART before anti-TB treatment, the later initiation of cART (more than 8 weeks after starting anti-TB treatment) was found to increase ...

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Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF

Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF

... ANOVA: Analysis of variance; BBB: Blood-brain barrier; BEC: Brain endothelial cells; BMEC: Brain microvascular endothelial cells; cART: Combination antiretroviral therapy; GM-CSF: Granul[r] ...

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Bone Safety of Dolutegravir-Containing Regimens in People Living with HIV: Results from a Real-World Cohort

<p>Bone Safety of Dolutegravir-Containing Regimens in People Living with HIV: Results from a Real-World Cohort</p>

... baseline; cART, combination antiretroviral therapy; PLWH, people living with HIV; BMI, body mass index; HCV, hepatitis C virus; HBV, hepatitis B virus; TDF, tenofovir disoproxil fumarate; TAF, ...

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Combination antiretroviral therapy and the risk of myocardial infarction

Combination antiretroviral therapy and the risk of myocardial infarction

... start therapy in dif- ferent calendar ...started therapy in different years may have had different profiles of risk for myocardial infarction, and if so, we may not have been able to adjust for all those ...

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Kidney transplant outcomes in HIV-positive patients: a systematic review and meta-analysis

Kidney transplant outcomes in HIV-positive patients: a systematic review and meta-analysis

... active antiretroviral therapy; KT: kidney transplanta- tion; cART : antiretroviral combination therapy; ESRD: end-stage renal disease; CD4 counts: CD4 T cell counts; AR: acute ...

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PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross sectional study

PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross sectional study

... and cART in the development of metabolic disturbances. Fourthly, cART may increase the risk for unfavorable cardiometabolic profile [2]; but in our study, cART characteristics were in- cluded in the ...

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Lamivudine/dolutegravir dual therapy in HIV infected, virologically suppressed patients

Lamivudine/dolutegravir dual therapy in HIV infected, virologically suppressed patients

... switch therapy was taken on clinical grounds as they presented a clinically relevant reason, either because of concomitant diseases, altered laboratory tests, drug adverse events or risk of drug-to-drug ...drug ...

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Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta analysis

Clinical determinants associated with quality of life for people who live with HIV/AIDS: a Meta analysis

... Active Antiretroviral Therapy (HAART) and ART interventions on QoL (intervention), participants that did not receive ART or HAART (comparison group), stud- ies that reported HIV/AIDS clinical information ...

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Markers of inflammation and coagulation indicate a prothrombotic state in HIV-infected patients with long-term use of antiretroviral therapy with or without abacavir

Markers of inflammation and coagulation indicate a prothrombotic state in HIV-infected patients with long-term use of antiretroviral therapy with or without abacavir

... of cART with undetectable or very low levels of viral replication had hsCRP levels >3 mg/L, which are strongly linked to cardiovascular disease in HIV-uninfected indi- viduals ...on cART with or without ...

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Update on current management of chronic kidney disease in patients with HIV infection

Update on current management of chronic kidney disease in patients with HIV infection

... TDF-based cART regimen has been associated with a greater eGFR decline compared with a non-TDF-based regi- men; the clinical importance of this association is not ...

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Self-collection based HPV testing for cervical cancer screening among women living with HIV in Uganda: a descriptive analysis of knowledge, intentions to screen and factors associated with HPV positivity

Self-collection based HPV testing for cervical cancer screening among women living with HIV in Uganda: a descriptive analysis of knowledge, intentions to screen and factors associated with HPV positivity

... Cervical cancer is a largely preventable and curable disease that affects over half a million women each year, with the greatest impact in low and middle income countries (LMIC) where access to screening, diagnosis, and ...

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Changes in mortality rates and causes of death in a population based cohort of persons living with and without HIV from 1996 to 2012

Changes in mortality rates and causes of death in a population based cohort of persons living with and without HIV from 1996 to 2012

... of cART in terms of non-HIV/AIDS-related causes; in 1996, only 21% of the deaths among HIV- infected individuals were attributable, as compared to 73% by ...

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Evaluation of HIV DNA and inflammatory markers in HIV infected individuals with different viral load patterns

Evaluation of HIV DNA and inflammatory markers in HIV infected individuals with different viral load patterns

... To assess microbial translocation, the soluble form of the LPS coreceptor CD14 (sCD14) was measured. Ninety-seven percent of patients showed detectable levels of sCD14. Significantly lower levels of sCD14 were detected ...

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