Conclusion: patient stratification and personalised treatment
Patient-specific data fusion for cancer stratification and personalised treatment
... the patient stratification studies for cancer types often do not produce patient subgroups that agree well with any clinical or survival data 6 ...tumor stratification 5 ...cancer ...
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The stratification of disease for personalised medicines
... Background The last 60 years has seen over 1,300 new medicines and vaccines discovered and developed by the pharmaceutical industry, approved for patient use by regulatory authorities around the world. These ...
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European Alliance for Personalised Medicine. INNOVATION and PATIENT ACCESS to PERSONALISED MEDICINE
... the patient can benefit from targeted therapies, requires information about the patient’s unique physiology, about the physiology, if applicable, of the virus, bacteria, or tumour, and about the patient’s ability ...
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Enhancing the patient involvement in outcomes: a study protocol of personalised outcome measurement in the treatment of substance misuse
... about personalised outcome assessment? ...misuse treatment, suggesting the relevance of PGOM as a method to personalise outcome measurement and, ultimately, guiding treatment ...and ...
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Development of a personalised approach to clinical decision making in psychological treatment services using routine patient data
... in patient outcomes (Bright et ...aid treatment selection decisions in CMHDs, despite several potential methods developed in datasets ...large patient datasets from these service, there is great ...
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Machine learning stratification for oncology patient survival
... to patient chemotherapy ...included patient treatment history as a feature of the ...chemotherapy treatment may then be causing problems with the identification of a minimal predictive gene ...
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Entropy-based consensus clustering for patient stratification
... Motivation: Patient stratification or disease subtyping is crucial for precision medicine and person- alized treatment of complex diseases. The increasing availability of high-throughput molecular ...
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Neuropathic Pain In Leprosy: Deep Profiling And Stratification Of Patient Groups
... leprosy patient seen, a detailed clinical history must include: any changes in skin colour and texture; area of sensory loss; weakness of the hands, feet, and eyes; and any signs of ...each patient, the ...
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Risk stratification by abbMEDS and CURB-65 in relation to treatment and clinical disposition of the septic patient at the emergency department: a cohort study
... This study has some limitations. First, we cannot ex- clude the risk of misclassification of measurements or data. However, we used standardized extraction forms and the main factors studied (laboratory values, anti- ...
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Risk stratification for women undergoing in-vitro fertilisation treatment
... IVF treatment 13 ...their treatment compared with normal BMI women 9,10 ...the patient to help improve their chances of ...the patient is obese the advice is to reach a target BMI of 30 or ...
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STRATIFICATION OF RISK FACTORS, DIAGNOSIS AND TREATMENT STRATEGIES FOR UROLITHIASIS
... for treatment and curing of ...hazard stratification in regards to spontaneous stone passage without sur- gical ...setting, patient body habitus, cost and resistance of ionizing ...
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Developing genomic models for cancer prevention and treatment stratification
... this conclusion, as shown by the lower number of gene sets significantly enriched in the signature of non-genotoxic carcinogens as compared with the genotoxic ...
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Proposition of patient stratification and parameter setting for mechanical traction in patients with LBP
... CONNECTING WITH OTHER FORMS OF THERAPY Mechanical traction in the authors' opinion should not be the only therapeutic procedure for the treatment of pain syndromes of the lumbar spine. The complexity of the ...
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Confidence interval estimation for the changepoint of treatment stratification in the presence of a qualitative covariate-treatment interaction
... “best” treatment to a ...same treatment; the choice of best treat- ment can depend on certain patient ...a patient-relevant outcome and a qualitative interaction between a continuous covariate ...
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Proteomic profiling in schizophrenia: enabling stratification for more effective treatment
... This approach was first described by the FDA in a white paper guidance that stipulated that increased knowledge about the biology of a biomarker and a robust association between the biomarker signal and the clinical ...
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The discovery and evaluation of treatment stratification biomarkers in epithelial ovarian cancer
... However there are still certain sites and volumes of disease which make complete debulking impossible even in the most skilled hands. There are likely to be biological determinants that affect how tumour cells invade and ...
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Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?
... The findings of this study are important to the development of a stratified (or personalised) approach to the management of diabetes. Identifying biomarkers (including clinical character- istics, metabolites, ...
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Effect of warm and cold stratification, and ethanol treatment on germination of Corylopsis seeds
... cold stratification and ethanol treatment on germination of Corylopsis ...warm stratification (WS) at 10, 15, 20, and 25°C followed by cold stratification (CS) at 5°C for 0, 1, 2, and 3 months ...
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Pre treatment risk stratification of prostate cancer patients:A critical review
... risk stratification systems A variety of alternative risk stratification systems, with the occasional direct comparison of models, have been ...risk stratification groups, but also includes ...
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Orphan Drugs & Personalised Medicine: The Patient Perspective
... • The new EU Data Protection Regulation tends to ignore the negative effect the new Regulation could have on scientific and medical research. • A viable alternative could be to have a [r] ...
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