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constitutional delay of growth and puberty

Association of ghrelin and leptin with reproductive hormones in constitutional delay of growth and puberty

Association of ghrelin and leptin with reproductive hormones in constitutional delay of growth and puberty

... Background: Constitutional delay of growth and puberty (CDGP) is a variation of the onset and timing of pubertal development without a defined endocrine ...in puberty initiation and ...

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Growth and segmental proportion in children with prepubertal growth delay and constitutional delay of growth and puberty: Natural history and the effect of therapeutic intervention

Growth and segmental proportion in children with prepubertal growth delay and constitutional delay of growth and puberty: Natural history and the effect of therapeutic intervention

... pubertal growth acceleration their growth velocity is extremely reduced with a nadir which may be below 3 cm per ...pubertal growth spurt is usually delayed by 2 to 4 years and the total period of ...

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Long-term Results of Treatment With Low-Dose Fluoxymesterone in Constitutional Delay of Growth and Puberty and in Genetic Short Stature

Long-term Results of Treatment With Low-Dose Fluoxymesterone in Constitutional Delay of Growth and Puberty and in Genetic Short Stature

... Abbreviations; CA, chronological age; HA, height age; BA, bone age; SA, sexual age; HPBI’, height prediction by Bayley-Pinneau; HPSMI, height prediction by sexual maturity index; HI, fin[r] ...

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Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit

... CDGP: Constitutional delay of growth and puberty; CI: Confidence interval; DP: Delayed puberty; F: Female; FDA: Food and Drug Administration; FSS: Familial short stature; GH: ...

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The Influence of GnRH Analog Therapy on Growth in Central Precocious Puberty

The Influence of GnRH Analog Therapy on Growth in Central Precocious Puberty

... Two subgroups were analyzed, according to the patients’ age when GnRHa therapy was in- troduced. Group 1 consisted of girls under the age of 7 at the start of the therapy, and Group 2 included girls aged 7 and older. ...

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Divergent roles of growth factors in the GnRH regulation of puberty in mice

Divergent roles of growth factors in the GnRH regulation of puberty in mice

... accelerate puberty in primates ...of puberty and colocalize with GnRH neurons (13, ...delayed puberty (Figures 4 and 5), providing direct evidence that IGF-1R signaling is necessary for the timely ...

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Predicting Heart Growth During Puberty: The Muscatine Study

Predicting Heart Growth During Puberty: The Muscatine Study

... Methodology. Using a repeated-measures design, we assessed aerobic fitness, FFM, fatness, weight, height, sexual maturation, resting BP, peak exercise BP, and LVM in 125 healthy children (mean baseline age: 10.5 years) ...

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Effects of Macro and Micro Minerals on Reproduction in Dairy Cattle - A Review

Effects of Macro and Micro Minerals on Reproduction in Dairy Cattle - A Review

... Cobalt deficiency is associated with an increased incidence of silent heat, nonfunctional ovaries, delayed onset of puberty, decreased conception rate, abortion and delayed uterine involution (Sathish Kumar, ...

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Adult Height in Children With Growth Hormone Deficiency Who Are Treated With Biosynthetic Growth Hormone: The National Cooperative Growth Study Experience

Adult Height in Children With Growth Hormone Deficiency Who Are Treated With Biosynthetic Growth Hormone: The National Cooperative Growth Study Experience

... Cooperative Growth Study (NCGS) was searched for patients who met the inclusion criteria of a diagnosis of idiopathic GHD, defined as a maximum stimulated GH level #10 mg/L and no evidence of an organic cause; ...

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Insight into human pubertal growth by applying the QEPS growth model

Insight into human pubertal growth by applying the QEPS growth model

... During puberty, the QEPS-model can mathematically delineate the total growth curve as well as identify growth resulting from both the specific pubertal growth P-function and the continuation ...

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Precocious Puberty : Clinical and Endocrine Profile and Predictors of Neurogenic Etiology in Girls with Central Precocious Puberty

Precocious Puberty : Clinical and Endocrine Profile and Predictors of Neurogenic Etiology in Girls with Central Precocious Puberty

... of puberty for general population (1, 2) or the onset of menstruation before ...(3). Puberty sets in with activation of the hypothalamic-pituitary-gonadal (HPG ...

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Impact of fetal and neonatal malnutrition on the onset of puberty and associated noncommunicable disease risks

Impact of fetal and neonatal malnutrition on the onset of puberty and associated noncommunicable disease risks

... of puberty. This characteristically long delay exposes the individual to an extremely high risk of pre- reproductive ...long delay is accounted for by increased communal investment by close kin and ...

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International Adoption, “Early” Puberty, and Underrecorded Age

International Adoption, “Early” Puberty, and Underrecorded Age

... to delay puberty, it is uncer- tain whether this treatment has resulted in any increase in height; it may have made the children shorter than their expected ...

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Early Puberty-Menarche After Precocious Pubarche: Relation to Prenatal Growth

Early Puberty-Menarche After Precocious Pubarche: Relation to Prenatal Growth

... considered to be reached when postmenarchal growth velocity had decreased to ⬍ 0.5 cm/year and/or when bone age was ⱖ 15 years. Target height was defined as midparental height, adjusted for female gender. BMI was ...

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Growth Delay in Homeless Children

Growth Delay in Homeless Children

... The domiciled children in this study had in creased weight-height percentiles when compared with both the NCHS standards and the homeless group. Even after we controlled for confounding [r] ...

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Age and Height at Diagnosis in Turner Syndrome: Influence of Parental Height

Age and Height at Diagnosis in Turner Syndrome: Influence of Parental Height

... Signs of spontaneous puberty occur in 10% to 20% of the patients with TS6”5’24 and are accom- panied by a small growth spurt.’5 Prepubertal growth and final adult height are, however, si[r] ...

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Oxandrolone Therapy in Constitutionally Delayed Growth and Puberty

Oxandrolone Therapy in Constitutionally Delayed Growth and Puberty

... Two smaller randomized,#{176}21 controlled studies of the effect of oxandrolone (Table 1) in boys with pubertal delay also show similar acute increases in growth velocity. As expected, b[r] ...

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Children With Idiopathic Short Stature Are Poor Eaters and Have Decreased Body Mass Index

Children With Idiopathic Short Stature Are Poor Eaters and Have Decreased Body Mass Index

... bone-age delay were much more pronounced in the group of index patients than in the group of siblings reflects the fact that the more severely affected child in a family is generally the one presented to the ...

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Silent Crooke’s cell corticotroph adenoma of the pituitary gland presenting as delayed puberty

Silent Crooke’s cell corticotroph adenoma of the pituitary gland presenting as delayed puberty

... CCA is an uncommon form of corticotroph adenomas, which is usually associated with an aggressive clinical course. Rarely, as in our case, CCAs can be clinically silent but require careful monitoring to identify the ...

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Constitutional delay of puberty: presentation and inheritance pattern in 48 familial cases

Constitutional delay of puberty: presentation and inheritance pattern in 48 familial cases

... delayed puberty in the other parent or his/her first-degree rela- tives); 2) bilineal families (either both parents affected or an unaffected parent having an affected sibling or par- ...

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