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corticobasal degeneration (CBD)

Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy

Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy

... with corticobasal degeneration (CBD) and progressive supranuclear palsy ...FTD, CBD and PSP using a multidimensional approach to assessment, which examines metacognitive knowledge of the ...

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Diffusion Tensor Imaging Shows Different Topographic Involvement of the Thalamus in Progressive Supranuclear Palsy and Corticobasal Degeneration

Diffusion Tensor Imaging Shows Different Topographic Involvement of the Thalamus in Progressive Supranuclear Palsy and Corticobasal Degeneration

... and corticobasal degeneration (CBD), postmortem studies show different topographic involvement of the thalamus, basal ganglia, and their cortical ...and CBD, particularly within the thalamus ...

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Imaging Pathologic Correlation in Corticobasal Degeneration

Imaging Pathologic Correlation in Corticobasal Degeneration

... of degeneration of the subthalamic nuclei, and 4) the presence or ab- sence of a lesion in the SCWM and whether the lesion constituted primary or secondary degeneration in ...2. Corticobasal ...

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Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-

Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-

... and corticobasal degeneration (CBD), show a distinct path- ology where 4R tau is selectively deposited [11, 12], and distribution of tau lesions is not skewed towards the ...and CBD are often ...

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Density and spatial pattern of β-amyloid (Aβ) deposits in corticobasal degeneration

Density and spatial pattern of β-amyloid (Aβ) deposits in corticobasal degeneration

... Corticobasal degeneration (CBD) is a rare, progressive movement disorder characterized neuropathologically by wide- spread neuronal and glial pathology including tau-immunoreactive neuronal ...

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Visual signs and symptoms of corticobasal degeneration

Visual signs and symptoms of corticobasal degeneration

... Corticobasal degeneration is a rare, progressive neurodegenerative disease and a member of the ‘parkinsonian’ group of disorders which also includes Parkinson’s disease, progressive supranuclear palsy, ...

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Dyspraxia in a patient with corticobasal degeneration: the role of visual and tactile inputs to action

Dyspraxia in a patient with corticobasal degeneration: the role of visual and tactile inputs to action

... Methods—The subject had clinically diag- nosed CBD, and exhibited alien limb behaviour and striking ideomotor dys- praxia. General neuropsychological evalu- ation focused on constructional and visuospatial ...

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Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy

Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy

... FAD, CBD and PSP ...In CBD patients, an extensive colocali- zation of p62/SQSTM1 and hyperphosphorylated tau was found mainly in threads (asterisks in ...

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Evaluation of Cortical Atrophy between Progressive Supranuclear Palsy and Corticobasal Degeneration by Hemispheric Surface Display of MR Images

Evaluation of Cortical Atrophy between Progressive Supranuclear Palsy and Corticobasal Degeneration by Hemispheric Surface Display of MR Images

... As shown in our study, visual atrophy rating re- sulted in more accurate discrimination of the two diseases than did volumetric results. This may be due to the limitation of volumetry, which cannot be used to measure ...

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Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy

Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy

... so-called CBD-pretangles are a random accumu- lation of tau-positive straight filaments, rarely evolving into so-called NFTs even when the filament density is ...in CBD (15–20 nm straight filaments or PHFs ...

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On the 'classification' of neurodegenerative disorders:discrete entities, overlap or continuum?

On the 'classification' of neurodegenerative disorders:discrete entities, overlap or continuum?

... Originally, the majority of neurodegenerative dis- orders were classified into two major molecular groups, viz., the tauopathies: AD, PiD, argyrophilic grain disease (AGD) [123], PSP, corticobasal ...

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Trigeminal neuralgia due to pontine infarction

Trigeminal neuralgia due to pontine infarction

... and corticobasal degeneration ...and CBD between 1970 and ...as CBD-like, 33 as PSP-like, and 13 with frontotempo- ral dementia with coexisting motor neuron disease ...neuron ...

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Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy

... Cerebellum; CBD: Corticobasal degeneration; CBS: Corticobasal syndrome; ELISA: Enzyme-linked immunosorbent assay; Fr: Frontal cortex; FTLD: Frontemporal lobar degeneration; FuG: ...

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Challenges and Opportunities in Atypical Parkinsonian Syndromes: Call to Action

<p>Challenges and Opportunities in Atypical Parkinsonian Syndromes: Call to Action</p>

... Abstract: Neurodegenerative diseases are a leading cause of disability and death in the United States, and the burden of rare neurodegenerative conditions such as atypical Parkinsonian syndromes is expected to grow in ...

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Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

... patients were assessed by consultant neurologists with ex- pertise in cognitive neurology and fulfilled consensus cri- teria for PCA and NIA-AA criteria for tAD respectively [11, 14]. PCA patients fulfilled Mendez et al. ...

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A comparison of visual problems in the parkinsonian syndromes

A comparison of visual problems in the parkinsonian syndromes

... and corticobasal degeneration ...than CBD or PSP and vertical supranuclear gaze palsy may be a significant feature of ...and CBD from ...

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Early-onset dementias: diagnostic and etiological considerations

Early-onset dementias: diagnostic and etiological considerations

... example, corticobasal degeneration (CBD), Pick’s disease, PSP), non-Tau patho- logies (for example, FTLD-TDP) and mixed amyloid and Tau pathology (for example, AD), making it more pathologically ...

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Alpha-synuclein and tau: teammates in neurodegeneration?

Alpha-synuclein and tau: teammates in neurodegeneration?

... AD: Alzheimer ’ s disease; ALS: Amyotrophic lateral sclerosis; α syn: Alpha-synuclein protein; DLB: Dementia with Lewy bodies; CBD: Corticobasal degeneration; FRET: Förster resonance ene[r] ...

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The predictive value of transcranial duplex sonography for the clinical diagnosis in undiagnosed parkinsonian syndromes: comparison with SPECT scans

The predictive value of transcranial duplex sonography for the clinical diagnosis in undiagnosed parkinsonian syndromes: comparison with SPECT scans

... CBD: corticobasal degeneration; DIP: drug induced par- kinsonism; DLBD: diffuse Lewy body disease; ET: essen- tial tremor; FP-CIT: 123I-Ioflupane; IPD: idiopathic Parkinson's disease; IBZM: ...

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Clinical Reasoning: A woman with rapidly progressive apraxia

Clinical Reasoning: A woman with rapidly progressive apraxia

... The differential diagnosis includes frontotemporal dementia, corticobasal degeneration, and other leukoencephalopathies such as metachromatic leukodystrophy, cerebral autosomal dominant [r] ...

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