Criteria for tissue plasminogen activator (tPA) therapy
With the use of tissue plasminogen activator (tpa) for
... softer tissue surrounded by pink, normal brain tissue on the brain ...the tissue that did not extend through the tissue as a blood vessel ...
7
The thrombolytic tissue-type plasminogen activator (tpa)
... thrombolytic tissue-type plasminogen activator (tPA) was approved in 1996 by the Food and Drug Adminis- tration for treatment of acute ischemic ...
5
Regulation of seizure spreading by neuroserpin and tissue type plasminogen activator is plasminogen independent
... Tissue-type plasminogen activator (tPA) is a highly specific serine proteinase expressed in the CNS during events that require neuronal ...contrast, plasminogen-deficient mice show a pattern ...
9
Clinical Outcomes of Endovascular Thrombectomy in Tissue Plasminogen Activator versus Non-Tissue Plasminogen Activator Patients at Primary Stroke Care Centers.
... endovascular therapy at two select rural primary stroke centers between 2011 and 2015 was ...Inclusion criteria were all anterior circulation large vessel occlusions within an 8 h time window from symptom ...
7
Clinical Outcomes of Endovascular Thrombectomy in Tissue Plasminogen Activator versus Non-Tissue Plasminogen Activator Patients at Primary Stroke Care Centers.
... intravenous tissue plasminogen activator (IV tPA) administration before endovascular intervention as compared to without at thrombectomy‑capable low‑volume centers on procedural aspects and patient ...
5
Tissue type plasminogen activator is a neuroprotectant in the mouse hippocampus
... Each observation was repeated in cultures from 3 different animals (n = 10). Early and delayed preconditioning with tPA. For early and delayed precondi- tioning, we used hippocampal neurons at 10 days in vitro. For early ...
13
Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects
... defining criteria were significant predic- tors for PAI-1 activity, while none of the diabetes related factors seemed to contribute to PAI-1 activity and tPA ...
9
Association of plasminogen activator inhibitor 1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects
... defining criteria were significant predic- tors for PAI-1 activity, while none of the diabetes related factors seemed to contribute to PAI-1 activity and tPA ...
9
Enzymatic vitreolysis with recombinant tissue plasminogen activator for vitreomacular traction
... Recombinant tissue plasminogen activator (rTPA) (Actilyse, manufactured by Boehringer Ingelheim Pharma KG, Ingelheim, Germany) is a specific serin ...converts plasminogen to plasmin due to its ...
10
Management of Plastic Bronchitis With Topical Tissue-type Plasminogen Activator
... 20,21 One child was treated successfully and safely with a home regimen of azi- thromycin and nebulized tPA. 21 Currently, data are limited regarding optimal treatment of plastic bronchitis, so the clinician must rely on ...
7
The Outcome of Treatment With Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke
... selection criteria and prescription dose to achieve better results of treatment with ...Keywords: Tissue plasminogen activator, Stroke, Thrombolytic ...
10
Bleeding Complications after Basilar Artery Fibrinolysis with Tissue Plasminogen Activator
... BACKGROUND AND PURPOSE: Fibrinolysis with local intraarterial urokinase infusion for basilar artery thrombosis has been associated with a low rate of spontaneous symptomatic cerebral hemorrhage, even when patients have ...
5
Complex formation of platelet thrombospondin with plasminogen Modulation of activation by tissue activator
... immunoelectrophoresis systems, complex formation was inhibited by 10 mM epsilon-amino- n-caproic acid, implying that there is a role for the lysine binding sites of Plg in mediating the interaction. TSP also formed a ...
10
Effectiveness and Safety of Tissue Plasminogen Activator in the Management of Complicated Parapneumonic Effusions
... tomy drainage alone. Initial use of tPA at HSC fo- cused on children who were believed to be at risk of a poorer outcome (eg, large multiple loculations not responding to initial thoracostomy drainage). There- fore, if ...
6
Outcome of stroke patients receiving different doses of recombinant tissue plasminogen activator
... 1) Doctor experience: if the doctor had repeated experi- ences of patients having (sHT) or dying after being given standard-dose tPA, the physician may decide to use low dose. 2) Patient’s condition: if a doctor thinks ...
8
Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle
... drug therapy can reduce mortality, and this therapeutic approach has been widely used in thrombosis ...available, tissue plasminogen activator (tPA) is currently the only US Food and Drug ...
13
Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator
... Keywords: Plasminogen activators, Fibrinolysins, Plasminogen activator inhibitor-1, Inhalational acute lung injury adhesions and removes organizing fibrinous material from the pleural space ...by ...
13
Quantitation of fragment X formation during thrombolytic therapy with streptokinase and tissue plasminogen activator
... J Clin Invest. 1987;79(6):1642-1647. https://doi.org/10.1172/JCI113001. We have determined the extent of fragment X formation during thrombolytic therapy by integration over time of the plasma fibrinopeptide B ...
7
Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface
... of plasminogen binding on activated platelet as well as stimulation of t-PA- dependent plasminogen activation by platelets to provide more efficient fibrin hydrolysis, give the evi- dence to suggest the ...
11
A biochemical study of tissue type plasminogen activator in bovine milk
... This field of research is receiving attention internationally. The Food Science Department of Purdue University is currently investigating the use of Fourier- transform infrared (FTIR) spectroscopy, in combination with ...
196