Cytokeratin-19
Prognostic and Predictive Value of Carcinoembryonic Antigen and Cytokeratin 19 Fragments Levels in Advanced Non Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib
... Purpose: The prognostic and predictive value of pretreatment serum levels of car- cinoembryonic antigen (CEA) and cytokeratin-19 fragments (CYFRA 21-1) were assessed in advanced non-small cell lung cancer ...
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Expression of E-Cadherin, Cytokeratin-14 and Cytokeratin-19 in tooth germ and Ameloblastoma
... E-Cadherin, Cytokeratin-14 and Cytokeratin-19 in tooth germ and ameloblastoma” was done in the Department of Oral Pathology and Microbiology, Tamil Nadu Government Dental College and Hospital, ...
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Evaluation the diagnostic and prognostic value of cytokeratin 19 (ck19) gene expression in Iraqi breast cancer patients
... cells. Cytokeratin-19 (CK-19), cytoskeletal component present in normal and cancerous epithelial cells, has been extensively used for the detection of breast cancer cells in mesenchymal tissues and ...
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The Role of Serum Cytokeratin 19 Fragment in Transarterial Infusion against Invasive Bladder Cancer
... Although NMP22 and BTA have been used as urinary markers of bladder cancers, no serum marker has been established. In this study, we investigated the correlation between the effect of treatment and serum CYFRA levels. ...
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The expression of cytokeratin 19 in lymph nodes was a poor prognostic factor for hepatocellular carcinoma after hepatic resection
... [22]. Differences in cytokeratin expression are routinely used to determine the primary cells of origin of malignant tumor [23,24]. In normal human liver, hepatocytes express CK8 and CK18, while biliary epithelial ...
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Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19 - liver cells deficient for p53 and Rb
... This study provides insights into the pathogenesis of the development of liver tumors after surgical resection or RFA treatment, a scenario that is often observed in human liver cancer patients that underwent surgical or ...
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Immunohistochemical Evaluation of Cytokeratin 19 and Calretinin in Odontogenic Cysts and Tumors
... filamen ts. These are six distinct ty pes of intermediate fila ments; keratin fila ments constitute ty pe I and type II inter mediates filamen ts with atleast 20 subtypes. A number of two gel electrophoresis experiments ...
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Detection of Circulating Tumor Cells in Breast Cancer Patients Using Cytokeratin 19 Real Time RT PCR
... In conclusion, we adapted and validated a detection meth- od for CTCs using RT-PCR for CK-19 mRNA expression. The current study suggested that CTC detection using RT-PCR for CK-19 mRNA expression may have a ...
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Evaluation of cytokeratin-19 in breast cancer tissue samples: a comparison of automatic and manual evaluations of scanned tissue microarray cylinders
... Many published studies have compared the results from automated procedures and from visual evaluation of DIs from a small portion of tissue in TMA cylinders [12,15]. Some studies have observed that the variability ...
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The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer
... Abbreviations used: CI – confidence interval; CK19 – cytokeratin 19; DF – disease-free survival; DR – distant disease recurrence; LBR:ANCT – associated non-cancerous tissue, lamin B re[r] ...
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... In a previous study [6], we analyzed the prognostic impor- tance of the circulating tumor markers (CTMs) cytokeratin 19 (CK19), CK20, epidermal growth factor receptor (EGFR) and human epidermal growth ...
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Comparison of tumor markers using different detection devices
... Conclusion: We developed a detection method for ultra-trace protein that can detect four tumor markers, namely carcinoembryonic antigen, cytokeratin-19 fragments, neuron-sp[r] ...
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<p>Clinical Value of Tumor Marker Index Based on Preoperative CYFRA 21-1 and SCC-Ag in the Evaluation of Prognosis and Treatment Effectiveness in Patients with Esophageal Squamous Cell Carcinoma</p>
... Presently, cytokeratin 19 fragment (CYFRA 21 – 1), squamous cell carcinoma antigen (SCC-Ag), carbohydrate antigen 72 – 4 are useful biomarkers for diagnosis, progression, and prognosis evaluation of ...
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Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte like cells
... In most instances, mature hepatocytes can undergo several cell divisions and are responsible for hepatic cell replacement. As a result, there has been great contro- versy about the existence and function of a liver stem ...
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Evaluation of anti PD 1 based therapy against triple negative breast cancer patient derived xenograft tumors engrafted in humanized mouse models
... PPTX 131 kb Abbreviations ANOVA: Analysis of variance; APC: Allophycocyanin; CK19: Cytokeratin 19; CPI: Checkpoint inhibitor; CTLA-4: Cytotoxic T-lymphocyte-associated protein 4; DFS: Di[r] ...
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Decision support systems for incurable non-small cell lung cancer: a systematic review
... 21-1: Cytokeratin-19 fragments; ds- GPA: Disease specific Graded Prognostic Assessment; DSS: Decision Support System(s); ECM: Extracranial metastases; EGFR: Epidermal growth factor receptor; EGFR-TKI: ...
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Generation of insulin-secreting cells from mouse gallbladder stem cells by small molecules in vitro
... GSCs: Gallbladder stem cells; EpCAM: Epithelial cell adhesion molecule; GFP: Green fluorescent protein; CK19: Cytokeratin 19; Alb: Albumin; STZ: Streptozotocin; KM: Kubota ’ s medium; aS[r] ...
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CYFRA 21-1 in urine: a diagnostic marker for endometriosis?
... Abstract: Diagnostic workup of endometriosis usually involves laparoscopic inspection and histological examination of biopsies. Unequivocal laboratory parameters for this ailment have not been available in routine ...
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Three are better than one: plasminogen receptors as cancer theranostic targets
... CK8: Cytokeratin 8; CK18: Cytokeratin 18; CK19: Cytokeratin 19; CRCC: Chromophobe renal cell carcinoma; EMT: Epithelial mesenchymal transition; EGF: Epidermal growth factor; ENOA: ...
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Risk factors of brain metastasis of lung squamous cell carcinoma: a retrospective analysis of 188 patients from single center
... Cyfra21-1: Cytokeratin 19 fragments; EGFR: Epidermal growth factor receptor; GPA: Graded prognostic assessment; KPS: Karnofsky performance status; NSCLC: Non-small cell lung cancer; NSE: Neuron-specific ...
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