Cytokine synthesis
Modulation of cytokine synthesis by bacterial components
... The simplest hypothesis to explain the pathology of periodontitis would be that bacterial components or products, released from the subgingival plaque, stimulate cells in the gingiva (both resident cells, such as ...
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Alterations with age in peripheral blood lymphocyte subpopulations and cytokine synthesis in beagles
... In summary, we analyzed the relationship between periph- eral blood leukocyte subpopulations and their cytokine synthesis and age in healthy dogs. First, the numbers of naive T cells decreased with age, ...
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Original Article Protective effects of astaxanthin against diabetic retinal vessels and pro-inflammatory cytokine synthesis
... Astaxanthin against diabetic retinal vessels and inflammatory Abbreviations: C, control rats; DM, diabetic rats; DM+AST, diabetic rats receiving astaxanthin; AGE, advanced glycation end [r] ...
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Regulation of macrophage subpopulations and their relationship to T cell function in the pathogenesis of asthma.
... (IL-Ip, TNFa, GM-CSF) or reactive chemicals (haptens) the cells undergo an activation process with increased expression of major histocompatability (MHC) molecules and costimulatory molecules and reduced capacity to ...
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Salivary and serum IL-10, TNF-α, TGF-β, VEGF levels in oropharyngeal squamous cell carcinoma and correlation with HPV and EBV infections
... CSIF, cytokine synthesis inhibitor factor; DNA, deoxy- ribonucleic acid; EBNA-2, Epstein-Barr nuclear antigen 2; EBV, Epstein-Barr virus; ELISA, enzyme-linked im- munosorbent assay; GCP, good clinical ...
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Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia
... Different MAPK signaling pathways are activated in T cells dependent on the costimulatory receptor engaged. The MAP kinase ERK is important for both stimuli. p38 MAPK activation is important for CD28 induced ...
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Angiotensin Converting Enzyme Gene Insertion(I) / Deletion(D) Polymorphism and its association with Type 2 Diabetics with Nephropathy.
... Chart- I AGE AND ITS RELATION WITH DIABETIC NEPHROPATHY Mesenchymal cells Proteolytic enzyme secretion Nucleic acid crosslinking Increased cytokine synthesis and release Macrophage AGE r[r] ...
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Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL 1 beta and IL 6
... Despite its failure to effect inhibition of CNS cytokine transcription, dexamethasone was successful in this study in suppressing systemic cytokines IL-1 b and IL-6 by approximately 80 and 90% respectively. This ...
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Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction- a novel mechanism for maintaining vascular function
... soluble cytokine receptors, to regu- late innate and adaptive immune ...pro-inflammatory cytokine synthesis or control pro- inflammatory cytokine-mediated cellular activities ...
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Interleukin 1 Induces HIV-1 Expression in Chronically Infected U1 Cells: Blockade by Interleukin 1 Receptor Antagonist and Tumor Necrosis Factor Binding Protein Type 1
... IL- I receptor antagonist inhibits IL- 1 -induced cytokine synthesis and blocks the binding of IL-I to its type II receptor on human mono-. cytes[r] ...
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Early down regulation of the pro inflammatory potential of monocytes is correlated to organ dysfunction in patients after severe multiple injury: a cohort study
... the cytokine cascade such as IL-6 and ...of cytokine blood levels in severely ill patients do not allow pre- cise determinations of cytokine synthesis and secretion in ...of cytokine ...
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Spermine Inhibition of Monocyte Activation and Inflammation
... Thus, spermine up- take is required for spermine suppression of monocyte cytokine synthesis, and increased spermine uptake in activated monocytes pro- vides a mechanism to prevent excess[r] ...
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Correlation of cytokine level with the severity of severe fever with thrombocytopenia syndrome
... Interferons are glycoprotein secreted by mononuclear leukocytes and lymphocytes in response to pathogens, such as viruses and bacteria, or tumor cells [14]. Based on the type of receptor, human interferons have been ...
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Infection of Primary Cultures of Human Kupffer Cells by Dengue Virus: No Viral Progeny Synthesis, but Cytokine Production Is Evident
... The synthesis of TNF-a, IFN-a, and IL-6 increased with time after infection (Table ...TNF-a synthesis were higher than those for mock-infected cells after 6 and 30 h, ...
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Synthesis of a novel cytokine and its gene (LD78) expressions in hematopoietic fresh tumor cells and cell lines
... LD78 gene transcripts were detected in eight of eight fresh samples of cells from patients with acute nonlymphocytic leukemia ANLL by Northern blot analysis.. ANLL cells with monocytic f[r] ...
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Evidence for cytokine inducible nitric oxide synthesis from L arginine in patients receiving interleukin 2 therapy
... An interferon-gamma, tumor necrosis factor, and interleukin-1-inducible, high-output pathway synthesizing nitric oxide (NO) from L-arginine was recently identified in rodents. High-dose interleukin-2 (IL-2) therapy is ...
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Blueprints of Signaling Interactions between Pattern Recognition Receptors: Implications for the Design of Vaccine Adjuvants
... particular, cytokine responses through dectin-1 signaling are dependent on these interactions, since stimulation with -glucan alone results in very limited cytokine ...
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Cytokine-induced killer cells/dendritic cells and cytokine-induced killer cells immunotherapy for the treatment of esophageal cancer in China: a meta-analysis
... 24. Li H, Ren XB, Zhang P, An XM, Liu H, Hao XS. 树突状细胞对CIK细 胞中CD4+CD25+ T细胞数量及免疫调节作用的影响 [Dendritic cells reduce the number and function of CD4+CD25+ cells in cytokine-in- duced killer cells]. Zhonghua Yi Xue Za ...
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Analysis of the Local and Systemic Cytokine Response Profiles in Patients with Community-Acquired Pneumonia. Relationship with Disease Severity and Outcomes.
... systemic cytokine responses in patients with Community-acquired pneumonia (CAP) and to develop a model to integrate multiple cytokine data in order to investigate the relationships of different ...
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A Role for TMEM150A in Cytokine Regulation.
... This model is in line with its relationship to both PI4KIII and DRAM family members that modulate autophagy, which are connected to, but not isolated from, the TLR4 immune response. Notably, NFkB, the canonical ...
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