D-Aspartate
D Aspartate, a Key Element for the Improvement of Sperm Quality
... acid, D-aspartic acid (D-Asp), for the improvement of sperm quality in sub-fertile ...[12,13]. D-Asp is the stereochemical enantiomer of naturally occurring L-aspartic acid, differing by the ...
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Production, purification and characterization of D aspartate oxidase from the fungus Trichoderma harzianum SKW 36
... of D-amino acid oxidizing enzymes. One enzyme was D-aspartate oxidase acting on acidic D-amino acids such as D-aspartate and D-glutamate and an- other one was ...
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Original Article Effects of N-methyl-D-aspartate receptor on remifentanil-induced hyperalgesia
... general anesthesia leading to activation of pro- tein kinase, especially calcium dependent cal- modulin and protein kinase C (PKC) [7]. (2) Pre- vious studies investigated the ERK level associ- ated with hyperalgesia, ...
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N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis
... The amino acid glutamate is the major excitatory neurotransmitter in the mammalian central nervous sys- tem (CNS). It can act on ionotropic (iGluR) and metabo- tropic (mGluR) receptors. iGluRs are ligand-gated non- ...
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Anti N Methyl D Aspartate Receptor Encephalitis with Concomitant Detection of Epstein Barr Virus
... Introduction: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an important cause of encephalitis worldwide. While some cases are associated with neoplasms, in the remaining cases the etiology is ...
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Atypical presentation of anti N methyl D aspartate receptor encephalitis: two case reports
... The first patient was an 8-year-old girl with normal psychomotor development. Over a 4-month period she developed behavioral problems, speech impairment, and deterioration in academic skills. Within 8 months from the ...
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The diffuse involvement of anti-N-methyl-D-aspartate receptor encephalitis in brain: a case report
... Anti-N-methyl-D-aspartate receptor (NMDAR) encephal- itis is a severe autoimmune disorder first described in 2007 [1]. It is associated with antibodies in the serum and cere- brospinal fluid against the ...
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Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons
... Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions. However in pathological ...
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Mercury-induced toxicity of rat cortical neurons is mediated through N-methyl-D-Aspartate receptors
... and mitochondrial function [20,21] (also see review [22]). Moreover, a large body of recent evidence has also drawn the link between mercury and glutamate- mediated excitotoxicity. For instance, mercury has been shown to ...
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Developmental attenuation of N-methyl-D-aspartate receptor subunit expression by microRNAs
... N-methyl-D-aspartate receptors (NMDARs) are a sub- type of ionotropic glutamate receptors and are widely expressed throughout the nervous system [1]. They are required for induction and expression of many ...
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Anti-N-methyl-D-aspartate receptor encephalitis with serum anti-thyroid antibodies and IgM antibodies against Epstein-Barr virus viral capsid antigen: a case report and one year follow-up
... anti-N-methyl-D- aspartate receptor antibodies in her cerebral spinal ...N-methyl-D- aspartate receptor subunit 1 positive ectopic immature nervous tissue and Epstein-Barr virus latent ...
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Anti-N-methyl-D-aspartate receptor encephalitis in China
... N-methyl-D-aspartate receptors (NMDARs) are mainly distributed in the central nervous system, and play important roles in the mechanisms of learning and memory. A newly discovered disease caused by ...
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Anti N methyl D aspartate receptor encephalitis with an imaging invisible ovarian teratoma: a case report
... Case presentation: A 25-year-old white woman with anti-N-methyl-D-aspartate receptor encephalitis presented with behavioral changes and seizures that were confirmed to be secondary to ...
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Molecular characterisation of the N-methyl-D-aspartate receptor expressed in mammalian cells
... In the co-transfection experiments cDNAs from two different species were used, a rat cDNA for the NMDARl-la subunit and a mouse cDNA for the NMDAR2A subunit. Since the rat and mouse NMDARl-la protein sequences are 99.8 % ...
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N methyl D aspartate receptors mediate chemoreflexes in the shorthorn sculpin Myoxocephalus scorpius
... Oxygen chemoreceptor In conclusion, these results suggest that NMDA reflexes were evoked by rapid hypoxia, NaCN added into the blood internal, 0.3 ml, 50 µg ml–1 and the mouth receptors [r] ...
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Induced synthesis of P450 aromatase and 17β estradiol by d aspartate in frog brain
... Distribution of P450 aro immunoreactivity in frog brain To our knowledge, this is the first detailed description of the anatomical distribution of aromatase enzyme in the brain of an adult amphibian. Immunohistochemical ...
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Immunopathological characterization of ovarian teratomas associated with anti-N-methyl-D-aspartate receptor encephalitis
... To be included, patients had to meet the recognized cri- teria for NMDAR-E associated with the presence of IgG directed against NMDAR in the CSF [7, 29]. Cases of NMDAR-E referred to the French Reference Center for ...
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Novel hypoglycemic injury mechanism: N methyl D aspartate receptor mediated white matter damage
... with aspartate release (‘standard ...extracellular aspartate release after about 20 ...increased aspartate release. (E) The tissue (or intracellular) content of aspartate, glutamate and ...
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Anti-<em>N</em>-methyl-D-aspartate-receptor encephalitis: diagnosis, optimal management, and challenges
... In addition, agitation, mood lability, impulsivity, hallucinations, insomnia, and self-harming behavior (eg, lip biting or skin picking) are common challenges for the treatment team, and often provide an impetus for ...
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N methyl D aspartate (NMDA) mediates vascular relaxation via nitric oxide (NO) in rats but not in mice
... Mean of the size current level of the transient amperometric NO related peaks resulting from addition of Krebs vehicle, 5 µl, Substance P 25 µM or NMDA 2.5 µM to aortic rings of CD1 mice[r] ...
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