DEAD-box RNA helicase 6
DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level
... HBV RNA via transcriptional regula- ...viral RNA synthesis by suppressing ...HBV RNA synthesis by ...the helicase motif are denoted, along with the DEAD ...the helicase motif of ...
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Centroid, a novel putative DEAD box RNA helicase maternal mRNA, is localized in the mitochondrial cloud in Xenopus laevis oocytes
... 1 6 9 PS S I C NRS LLVS A D T G S G K T ASF LVPIIA H C S H V R S E R C T D - K Q GPLAI VLAP T R E LC LQVEEQ A KVLG KG L P- F KTALVV G GDP LA QQI YRI E N G I E LIV GT P G R LIDL L M K H NVDLN K V D V FVLD EVDC LLE ...
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The DEAD box RNA helicase Vad1 regulates multiple virulence associated genes in Cryptococcus neoformans
... Next, we proceeded to characterize the 3 transcripts reduced in the Δvad1 mutant in parallel to the virulence factor laccase. As shown in Figure 6, 1 fragment was subcloned and sequenced and found to be nearly ...
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Regulation of Notch Signaling by an Evolutionary Conserved DEAD Box RNA Helicase, Maheshvara in Drosophila melanogaster
... marginally suppressed the reduced eye phenotype in 32% of the eyes examined (n = 29; Figure 4F). Further, the mutant alleles in combination with the eyeless-GAL4 driver had no effect on the eye size, clearly ...
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Unexpected roles for DEAD box protein 3 in viral RNA sensing pathways
... 6 Hogbom, M., Collins, R., van den Berg, S., Jenvert, R. M., Karlberg, T., Kotenyova, T., Flores, A., Karlsson Hedestam, G. B. and Schiavone, L. H., Crystal structure of conserved domains 1 and 2 of the human ...
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DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids
... (Fig. 6 and 7), it is possible that the trace amount of DDX3 detected following proteinase K treatment may represent residual DDX3 molecules remain- ing due to incomplete ...the helicase motif was changed ...
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The QRxGRxGRxxxG motif of the vaccinia virus DExH box RNA helicase NPH-II is required for ATP hydrolysis and RNA unwinding but not for RNA binding.
... DExH box family includes many other proteins that are not shown in this ...the DEAD box protein eIF-4A are shown below the DExH ...human helicase A (HuHelA) (L13848); bovine helicase 2 ...
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Involvement of a Toxoplasma DEAD-box RNA Helicase in Post-transcriptional Gene Regulation
... Studies by Sibley and Boothroyd (1992) sought to determine the variation in parasitic strains by means of polymerase chain reaction (PCR) and restriction fragment length polymorphisms (RFLPs) [10]. In the study, 28 ...
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A HIV 1 Tat mutant protein disrupts HIV 1 Rev function by targeting the DEAD box RNA helicase DDX1
... permeabilized with 0.1% (v/v) Triton X-100 for 15 min and blocked in 10% (v/v) normal goat serum (Sapphire Bioscience) for 15 min. Endogenous DDX1 protein was detected with a rabbit anti-DDX1 polyclonal anti- body. ...
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SpolvlgA is a DDX3/PL10-related DEAD-box RNA helicase expressed in blastomeres and embryonic cells in planarian embryonic development
... Figure 4. SpolvlgA expression in late developmental stages of S. polychroa. a, c, e, h Schematic representa- tions of S. polychroa developmental stages 5 to 8. b, d, g, j, k SpolvlgA whole mount in situ hybridizations. ...
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DEAD box helicase DP103 defines metastatic potential of human breast cancers
... ure 6, B and ...the helicase families, of which DP103 is a member, share several conserved motifs, including the Walker A and B motifs, which are involved in the binding of nucleoside triphosphates required ...
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Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer
... Different levels of interference have been suggested for DDX3 in the Wnt-signaling pathway. In contrast with our findings, Cruciat, et al. found that DDX3 inhibition had no effect on Wnt signaling activity after ...
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Conserved requirement for DEAD box RNA helicase Gemin3 in Drosophila oogenesis
... stage 6, the chromo- somes dissociate into 32 pairs of chromatids so that for the rest of oogenesis, the chromosomes are diffuse and uniformly distributed throughout the nucleus, with such a change in chromosome ...
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The DEAD box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish
... Total RNA from 100 control and ddx39ab mutant 24 hpf embryos was isolated using TRIzol reagent. Two biological replicates for each group (control and ddx39ab mutant) were processed and sequenced. Sequencing ...
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Transcriptome Sequencing Reveals Novel Candidate Genes for Cardinium hertigii-Caused Cytoplasmic Incompatibility and Host-Cell Interaction
... Conclusions. Here, we provide the first insight into gene expression of the CI- causing Cardinium strain cEper1 in its natural host. This bacterium shows very little homology to CI Wolbachia, but Cardinium expression ...
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The RNA helicase A in malignant transformation
... High-throughput transcriptome analyses of Ewing sarcoma cells irradiated with UV light revealed a subset of genes and alternative splicing events that are regulated by this genotoxic stress [19]. Among them, the gene ...
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Alterations in the expression of DEAD box and other RNA binding proteins during HIV 1 replication
... the DEAD box proteins, we noted that two genes encoding DEAD box proteins, DDX18, a DEAD-box protein induced by Myc and Max [35] and DDX39, (or URH49), a DEAD-box ...
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The Me31B DEAD Box Helicase Localizes to Postsynaptic Foci and Regulates Expression of a CaMKII Reporter mRNA in Dendrites of Drosophila Olfactory Projection Neurons
... Citation: Hillebrand J, Pan K, Kokaram A, Barbee S, Parker R and Ramaswami M (2010) The Me31B DEAD-box helicase localizes to postsynaptic foci and regulates expression of a CaMKII re[r] ...
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Mutational analysis of vaccinia virus nucleoside triphosphate phosphohydrolase II, a DExH box RNA helicase.
... essential RNA helicase that cat- alyzes unidirectional unwinding of 3 9 -tailed duplex RNAs in the presence of a divalent cation and any common nucleoside triphosphates (NTPs) or deoxy-NTPs (dNTPs) (31, ...
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An Essential Role for the Saccharomyces cerevisiae DEAD-Box Helicase DHH1 in G1/S DNA-Damage Checkpoint Recovery
... a DEAD-box RNA helicase orthologous to the human putative proto-oncogene p54/RCK, is important in release from DNA-damage-induced cell cycle arrest at the G1/S ...
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