Decreased expression with the rare allele at -308
A Coalescent Model of Ancestry for a Rare Allele
... copies at present. coalescence times. The remainder of the article is organized as follows. In the next section, we describe a coalescent for a random tion leads to a one-generation inbreeding ratio that sample of ...
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Decreased expression of p73 in colorectal cancer
... the expression of p73 gene and protein in this type of cancer are scarce and unequivocal ...the expression of the TP73 gene in paired tumor-surgical margin specimens of CRC patients at the mRNA and protein ...
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Advances in the identification and analysis of allele-specific expression
... ASE in earlier studies. Probes were designed for the mismatch base to have a balanced T m on either side, thus placing it at the most thermodynamically disruptive location. Thirdly, the necessity of a SNP to reside ...
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Visualizing Allele Specific Expression In Single Cells
... With this approach, the SNP oligonucleotides will not cross-hybridize, giving us the ability to discriminate between a single base pair di↵erence, but there remains another specificity challenge. Since they are comprised ...
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Decreased PCSK9 expression in human hepatocellular carcinoma
... and fuel the mitochondrial TCA cycle, oxidative phos- phorylation, and ATP production within the cancer cell. Conclusion In conclusion, the decreased PCSK9 expression in HCC is suggestive of alterations in ...
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Global Analysis of Allele-Specific Expression in Arabidopsis thaliana
... Gene expression is a complex trait determined by various genetic and nongenetic ...with allele-specific expression, and 1688 genes controlled by composite trans-regulatory ...of ...
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Loss of RNA expression and allele-specific expression associated with congenital heart disease
... same allele has the potential to introduce error into allele bias and statistical assessment of ...minimum allele bias (4 to 7-fold) and minimum read depth of monoallelic SNPs (4, 5, y 10) in each ...
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Enhanced Ratio of Signals Enables Digital Mutation Scanning for Rare Allele Detection
... The use of droplet digital PCR (ddPCR) for low-level DNA mutation detection in cancer, prenatal diagnosis, and infectious diseases is growing rapidly. However, although ddPCR has been implemented successfully for ...
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Novel Method for Analysis of Allele Specific Expression in Triploid Oryzias latipes Reveals Consistent Pattern of Allele Exclusion
... Using the set of cDNA records from the ENSEMBL 65 medaka genome annotation as our reference, we initially detected 250,982 single nucleotide variant positions where at least one of the three parent strains differed from ...
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Decreased Expression of 15 hydroxyprostaglandin Dehydrogenase in Gastric Carcinomas
... by decreased gene expression, and expression was even induced in 3 prostate carcinoma samples, clearly showing CpG ...negligible expression of the ...Snail expression correlates well ...
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Decreased Dp71 expression is associated with gastric adenocarcinoma prognosis
... defective expression of Dp71 is related only with certain types of cancers, such as gastric cancer, as shown by the our ...its decreased expression in gastric ...the decreased Dp71 protein ...
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Decreased Expression of CDC25A in Azoospermia as the Etiology of Spermatogenesis Failure.
... Abstract Background: Spermatogenesis is a tightly regulated developmental process of male germ cells. The stages in spermatogenesis are mitosis, meiosis and spermiogenesis. One of the genes playing a role in meiosis is ...
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Decreased expression of LATS1 is correlated with the progression and prognosis of glioma
... lentivirus expression vector; 3) The LATS1 sequence was confirmed by sequence ...GFP expression were selected to expand culture and total RNA of all single cell clones were isolated and quantitative ...
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HLA-DR expression on monocytes is decreased in polytraumatized patients
... HLA-DR expression in volunteers nor the HLA- DR expression after surgery had been analysed as con- trol ...HLA-DR expression of polytrauma patients with sepsis and with- out sepsis could be found in ...
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Decreased Expression of CDC25A in Azoospermia as the Etiology of Spermatogenesis Failure
... Quantitative analysis of gene expression was as- sessed by the method Livak (16). To obtain effi- ciency value and cycle threshold (Ct), amplifica- tion with quantitative real-time (qRT) PCR ex- pression was ...
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Moderate the MAOA-L Allele Expression with CRISPR/Cas9 System
... The MAOA-L allele activity can cause antisocial behavior in both healthy and 12.. unhealthy people.[r] ...
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A Rare and Pure Expression of Boundless Hawaiian Living
... Kukui‘ula is envisioned to become Kaua‘i’s Living Garden. Working with the National Tropical Botanical Gardens, Kukui‘ula plans to invest over $85 million in rare and exotic indigenous gardens. Like a spectacular ...
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Original Article Decreased expression of TFPI-2 correlated with increased expression of CD133 in cholangiocarcinoma
... TFPI-2 expression plays a significant role in inhibiting cell migration and tumor ...the expression of TFPI-2 and its possible correlation with the expression of CD133 in cholangiocarcinoma remains ...
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Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma
... Disruption of this equilibrium is closely connected to the commencement and development of many types of cancers, and it represents a valuable target for antitumor therapy. 13,14 Several markers have been shown to ...
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Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene
... to allele-speci- fic expression, it should be detectable through allele-spe- cific association of CTCF and ...monoallelic expression in a pedigree of LCLs correlates with mono- allelic binding ...
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