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diabetes (ranging from predominantly insulin resistance with

Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

... demonstrated from all epidemiological ...relative insulin secretion and peripheral insulin resistance [7, ...with diabetes have not been fully ...in insulin secretion, but it is ...

10

Treating dual defects in diabetes: Insulin resistance and insulin secretion

Treating dual defects in diabetes: Insulin resistance and insulin secretion

... lipids from the ...storage from visceral fat to the less metabolically active subcutaneous depots, resulting in improved insulin sensitivity despite an increase in total body ...

7

Regulation of Plasma Triglycerides in Insulin Resistance and Diabetes

Regulation of Plasma Triglycerides in Insulin Resistance and Diabetes

... that insulin not only stimulates lipogenesis but also plays a key role in determining whether apo B is targeted for secretion or degradation ...target insulin for ...in insulin treated hepatocytes ...

9

Type 1 Diabetes Reflection on Insulin Resistance

Type 1 Diabetes Reflection on Insulin Resistance

... of diabetes below 39 years of age, an acute presentation with or without ketosis with insulin dependence, as evidenced by a deficient C-peptide secretion (when feasible) ...of diabetes of at least ...

5

Insulin Secretory and Insulin Resistance Defects in Type 2 Diabetes Mellitus

Insulin Secretory and Insulin Resistance Defects in Type 2 Diabetes Mellitus

... the insulin receptor; tyrosine phosphorylation of insulin receptor substrates activates phosphoinositide­3 kinase (PI3K), with downstream­ effects to prom­ote glycolysis, glycogen storage, protein ...

12

Insights into insulin resistance and type 2 diabetes from knockout mouse models

Insights into insulin resistance and type 2 diabetes from knockout mouse models

... states. Insulin resistance is seen in animals of both sexes, as evidenced by five- to sixfold higher postprandial hyperinsulinemia and impaired glucose response to insulin tolerance ...

8

Dynamical models for diabetes: insights into insulin resistance and type 1 diabetes

Dynamical models for diabetes: insights into insulin resistance and type 1 diabetes

... parameters from day to day, and also with different meal sizes ...sex, diabetes duration and glycemic ...different from the original minimal models and need to be discussed in some ...

135

Neurohormonal Mechanisms in Insulin Resistance and Type 2 Diabetes

Neurohormonal Mechanisms in Insulin Resistance and Type 2 Diabetes

... synthesized from cholesterol in the adrenal ...secreted from the hypothalamus and stimulates the release of adrenocorticotropic hormone (ACTH) from the pituitary, which stimulates the synthesis, ...

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ADIPONECTIN AND INSULIN RESISTANCE IN PRE-DIABETES AND EARLY TYPE 2 DIABETES MELLITUS

ADIPONECTIN AND INSULIN RESISTANCE IN PRE-DIABETES AND EARLY TYPE 2 DIABETES MELLITUS

... 2 diabetes group, whereas in IGT and normal glucose tolerance subjects adiponectin levels were significantly ...2 diabetes Caucasian subjects, and in both groups adi- ponectin levels were lower than in ...

8

Insulin resistance and associated factors in patients with Type 1 Diabetes

Insulin resistance and associated factors in patients with Type 1 Diabetes

... The original data from the formulas was calculated and di- vided into quartiles because the formulas do not have cut- off values for comparative analyses. We divided patients into three groups (1st quartile, 2nd + ...

10

Diet to Prevent and Reverse Insulin Resistance and Type 2 Diabetes

Diet to Prevent and Reverse Insulin Resistance and Type 2 Diabetes

... 4. Surgical treatment of obesity that resulted in a 16% reduction in initial body weight after 8 years cut the risk of developing type-2 DM by more than 6-fold compared to control subjects who did not get the surgery or ...

10

A novel botanical formula prevents diabetes by improving insulin resistance

A novel botanical formula prevents diabetes by improving insulin resistance

... A 96-well, cell-free α-amylase assay was established by using 2-chloro-p-nitrophenyl-α-D-maltotrioside (CNPG 3) as a substrate in an assay buffer which was prepared by adding 14.5 g sodium chloride, 0.15 g calcium chlor- ...

10

Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

... human insulin (Humulin-R, Eli Lilly, Indiana, IN, USA) was administered via the vein, and a blood sample was obtained from the opposite vein at 0, 3, 6, 9, 12, and 15 ...The insulin sensitivity index ...

7

A review of recent evidence relating to sugars, insulin resistance and diabetes

A review of recent evidence relating to sugars, insulin resistance and diabetes

... obesity, insulin resistance and ...derived from cross-sectional surveys or ecological observations, but there are also prospective cohort studies and controlled intervention trials which have ...

7

Effects of Caffeine and Coffee on Diabetes, Insulin Resistance Syndrome & Hypoglycemia

Effects of Caffeine and Coffee on Diabetes, Insulin Resistance Syndrome & Hypoglycemia

... Inc Diabetes, particularly Type 2, is a growing health ...have diabetes, although only 13 million are currently ...of diabetes prevalence are rising: ...year. Diabetes is the sixth leading ...

8

Endothelial dysfunction: Mechanisms and reversal in insulin resistance and diabetes mellitus

Endothelial dysfunction: Mechanisms and reversal in insulin resistance and diabetes mellitus

... prevalent from the fourth decade of ...vivo, from an age and abnormalities of flow-mediated dilatation have been detected in a wide range of young individuals with risk factors for cardiovascular ...

258

Receptiveness and resistance: perceptions of insulin use in Type 2 diabetes

Receptiveness and resistance: perceptions of insulin use in Type 2 diabetes

... or diabetes-specific emotional ...negative insulin appraisals has been demonstrated after insulin initiation and, thus, insulin uptake has been assumed to be synonymous with minimal ...using ...

451

Four‑Stage Evolution of Diabetes or Whole Body Insulin Resistance (WBIR): Debunking of the Lipid‑Induced Insulin Resistance (LIIR) and Proposing of the Glycation‑Induced Insulin Resistance (GIIR)

Four‑Stage Evolution of Diabetes or Whole Body Insulin Resistance (WBIR): Debunking of the Lipid‑Induced Insulin Resistance (LIIR) and Proposing of the Glycation‑Induced Insulin Resistance (GIIR)

... of diabetes from rapid weight gain to visceral obesity to rapid weight loss to full-blown diabetic state seems to comply rather well with the natural development history of diabetes ...observed ...

32

Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy

Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy

... improved from 178±51 to 114±18 mg/ dL. The insulin dose used for glycemic control was ...NPH insulin was used in 51 patients for glycemic control, sulfonylurea instead of NPH insu- lin was used at ...

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