Differentially methylated genes (DMG)
Identification of four differentially methylated genes as prognostic signatures for stage I lung adenocarcinoma
... downloaded methylated DNA data of LUAD ...151 differentially methylated genes related to relapse-free survival (RFS) of patients with ...hub genes were identified in PPI net- work, with ...
8
Epigenetic signature of differentially methylated genes in cutaneous melanoma
... 514 genes emerged after overlap- ping the sets of DMGs observed in melanomas carrying different sets of driver ...145 genes with significant DNA methylation differences between the two ...514 DMG ...
5
Identification of differentially methylated genes in the malignant transformation of ovarian endometriosis
... tially methylated candidate genes related to the malignant transformation of ovarian EMS by ...ferentially methylated candidate genes were identified as potentially related to the malignant ...
7
Dnmt1 is essential for egg production and embryo viability in the large milkweed bug, Oncopeltus fasciatus
... of genes with similar changes to expression and DNA ...of differentially methylated ...for genes that are differentially CG- methylated between ...of genes that are ...
14
Original Article Genome-wide DNA methylation and transcriptome changes in Mycobacterium tuberculosis with rifampicin and isoniazid resistance
... and differentially expressed genes in rifampicin or isoniazid resis- tant ...of Genes and Genomes (KEGG) biological pathway analysis and meth- ylated regulatory network analysis were conducted by ...
10
DNA methylation biomarkers for hepatocellular carcinoma
... many genes has been demonstrated to date in the context of HCC, a com- plete interaction network documenting the relation- ship between said genes remains to be ...and genes mediating the biological ...
13
Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome
... constitutively methylated probes in more than 80% of healthy control samples (β ≥ ...project.org). Genes which were differentially methylated between reactive (R) - and known clonal and ...
10
Maternal genome wide DNA methylation profiling in gestational diabetes shows distinctive disease associated changes relative to matched healthy pregnancies
... We identified 2 differentially methylated genes that shared identity with genes previously described in studies that interrogated placenta and umbilical cord blood samples and, in these [r] ...
30
Genome-wide differences in DNA methylation changes in caprine ovaries between oestrous and dioestrous phases
... of genes and gene products. In this study, differentially meth- ylated genes were enriched in 168 functional ...of genes have different methylation levels between oestrus and dioestrus, ...
8
Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer
... suppressor genes, hub genes and their pathways by combined bioinformatics ...(GEO). Differentially methylated genes (DMGs) were identified by the R package minfi and ...
23
Modulation of Cellular CpG DNA Methylation by Kaposi's Sarcoma-Associated Herpesvirus
... many differentially methylated genes and may explain the unique pattern of gene expression in this lymphoma, this analysis still lacks a direct connection between KSHV infection and cellular DNA ...
19
Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming
... The EDs used were vinclozolin (ChemService Catalog no. PS-1049; Sigma, USA), bis(2-ethylhexyl) phthalate (Selectophore, (DEHP), Catalog no. 80030; Fluka/Sigma Inc.), and bisphenol A (Catalog no. 239658; Sigma Aldrich ...
24
DNA methylation and smoking in Korean adults: epigenome-wide association study
... whether genes with differential Table 6 Look-up in the Korean COPD cohort of CpGs reported at least two epigenome-wide association studies (70 CpGs at FDR g < ...
17
Tweet
... Global DNA methylation in VAT and lymphocytes was measured using an EpiJET DNA Methylation Analysis Kit (Thermo Fisher Scientific) according to the manufactur- ers’ protocol. Briefly, genomic DNA (500 ng from VAT and 200 ...
9
Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer
... significantly differentially genes identified PPAR signalling, arachidonic acid metab- olism, and B cell receptor signaling ...in genes of the arachidonic acid metabolism (AAM) ...stress-related ...
12
An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype
... [6]. Differentially methylated loci (DML) involve many key genes implicated in inflammation, immune responses, cell-cell interactions, and matrix ...of differentially methylated ...
12
Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study
... the differentially methylated regions (DMRs) of three imprinted genes, H19 , GNAS , and DIRAS3 , using combined bisulfite PCR restriction analysis and bisulfite sequencing in sperm obtained from 135 ...
10
Exploring the molecular causes of hepatitis B virus vaccination response: an approach with epigenomic and transcriptomic data
... Given the importance of the clinical phenomenon (infection rate in Southeast Asia, parts of China and trop- ical Africa above >8% [11]) and the numerous computa- tional issues involved in the analysis of methylation ...
8
Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers
... DNA methylation alteration has been observed in vari- ous cancers and is considered to be a cause of carcino- genesis. Global hypomethylation is frequently seen in highly and moderately repeated DNA sequences and plays a ...
11
Differential DNA methylation marks and gene comethylation of COPD in African-Americans with COPD exacerbations
... multiple genes re- lated to obstructive lung disease and ...the genes we identified, they represent promising genes for mechanistic investigations of COPD in AA and for the consideration of ...
15