Dihydropyridine derivatives
EFFECT OF SOLVENT AND CATALYSIS ON SYNTHESIS OF DIHYDROPYRIDINE DERIVATIVES
... of dihydropyridine derivatives have been reported via a multi component reaction in the presence and absence of ammonium iron(II) ...substituted dihydropyridine derivatives were synthesized ...
11
Synthesis and anticonvulsant activity of a new series of 1,4-dihydropyridine derivatives
... A series of 1,4-dihydropyridine derivatives (1a–g) were prepared from three compounds condensation of Hantzsch synthesis. A new series of ...
7
SYNTHESIS, CHARACTERIZATION AND DOCKING STUDIES OF SOME NOVEL DIHYDROPYRIDINE DERIVATIVES
... The synthesis of a novel dihydropyridine derivatives bearing dimedone as an excellent precursor has been achieved by applying three component Hantzsch condensation. The newly synthesized compounds were ...
13
One Pot Multi Component Synthesis of Novel Dihydropyridine Derivatives
... The development of efficient and versatile catalytic systems for Hantzsch reaction is an active on-going research area and thus, there is a scope for further improvement toward milder reaction conditions, variations of ...
5
Synthesis and biological screening of 1,4 dihydropyridine derivatives containing benzothiazolyl moiety
... We have developed an economical, solvent free, very efficient microwave assisted protocol for the synthesis of N-(6-nitrobenzothiazolyl)-2,3,5,6-tetrasubstituted-4-(aryl)-1,4-dihydropyridines which can be a viable ...
14
Anticonvulsant, analgesic and anti inflammatory activities of some novel pyrrole and 1,4 dihydropyridine derivatives
... In this work we reported the synthesis some pyrrole and 1,4-dihydropyridine derivatives and evaluation of pharmacological activity. Synthesized compounds were confirmed by IR, ¹H NMR, 13 C NMR, Mass ...
7
An efficient One pot Synthesis of 1, 4 Dihydropyridine Derivatives under Solvent free Condition
... [7-12]. Dihydropyridine bases drugs such as nifedipine nicoridipine, amlodipine and many others are used in the treatment of hypertension and ...cerbrocrast. Dihydropyridine derivatives have been ...
6
An Efficient Protocol for Synthesis of 1,4-dihydropyridine Derivatives by Using Graphene Oxide Nano Particles as a Catalyst
... An efficient protocol was established for synthesis of 1,4-dihydropyridines via one pot condensation of aromatic aldehydes, -dicarbonyl compounds and ammonium acetate at reflux condition by using Graphene Oxide ...
7
Synthesis and Biological Evaluation of some Novel Dihydropyridine Derivatives of 3 ARYL 2 ISOBUTANOYL N PHENYL ACRYLAMIDE Analogue
... of dihydropyridine is ...methyl-5-[n-phenyl-aminocarbonyl]-1,4-dihydropyridine-3-carboxylates.The Dihydropyridine derivatives of Type (1a-l) have been synthesized by the condensation of ...
7
VIRTUAL TOXICITY STUDIES OF NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES
... same derivatives offer positive contribution for the probability of skin irritation (V ...the derivatives other than 2A-2A’ and 2C’ has shown value of 1 and so are most likely to produce a positive ...
5
Microwave Assisted Synthesis and Evaluation for Anticonvulsant Activity of Some 1,4 Dihydropyridine Derivatives
... bioactive derivatives of 3,3’-(2, 6-dimethyl-4-substituted aryl-1, 4-dihydropyridine-3,5-diyl)-bis-(N-benzylidene-1H- 1,2,4-triazol-5-amine) were synthesized under microwave ...
6
ZrO2 nanopowder catalyzed one pot green synthesis of Hantzsch 1,4 dihydropyridine derivatives under dry media
... Multicomponent condensation strategies offer significant advantages over conventional linear-type synthesis in providing products with the diversity needed for the discovery of new lead compounds or lead optimization ...
6
Synthesis of Novel 1,4- Dihydropyridine Derivatives Bearing Biphenyl-2'-Tetrazole Substitution as Potential Dual Angiotensin II Receptors and Calcium Channel Blockers
... 8.6-10.6 ppm as a broad singlet, 4.8-5.1 ppm as a singlet, 3.7-4.1 as multiplet and 3.4-3.6 ppm as a singlet respectively. The six hydrogens of 2,6-dimethyl-DHP are appeared as a singlet in 2.2 ppm. The 1 H NMR spectrums ...
9
QSAR STUDIES ON NOVEL 1, 4 DIHYDROPYRIDINE DERIVATIVES
... 5. Rajesh H. Tale, Atish H. Rodge, Girish D. Hatnapure, Ashish P. Keche, Kalpana M. Patil and Rajendra P. Pawar: The synthesis, anti-inflammatory, and anti-microbial activity evaluation of new series of 4-(3-arylureido) ...
8
Synthesis and Biological Evaluation of Some Heterocyclic Derivatives of N Aryl 3 Cyclopropyl 3 Oxo Propanamide Analogue
... Dihydropyridine derivatives like some new Methyl-5-arylamido-4-(o-chlorophenyl)-6-cyclopropyl-2-methyl-1,4-dihydropyridine-3- carboxylate derivatives of type (2a-l) have been synthesized by ...
6
Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives
... 9. Ghodsi S., Alipour E., Amini M., Miri R., Tagi-Ganji K.M., Mir Khani H., and Shafiee A. The Synthesis and Characterization of New Asymmetrical Dihydropyridine Derivatives Containing a ...
5
β-Ketoesters in Heterocylic Synthesis: Synthesis of new Dihydropyridine, Tetrahydropyrimidine, Pyrazole, Aminothiophene, Pyrazolopyrimidine Derivatives, and investigation of their antimicrobial activity
... 1,4- dihydropyridine derivatives ...pyrazolopyrimidine derivatives 18a,b ...pyrazole derivatives 23a,b could be prepared from β-ketoester ...tetrahydropyrimidine derivatives 25a-d were ...
12
A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
... Abstract - An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl ...
7
Efficient Procedure for Preparation of 1,4-Dihydropyridines under Green Chemistry Conditions
... 1,4-dihydropyridine derivatives, herein an efficient, economic, straightforward multicomponent reaction involving ethylacetoacetate, arylaldehyde and ammonium acetate in ...
5
Novel procedure for preparation of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
... An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three- component reaction of various aldehydes, ethyl acetoacetate, ...
6