Diltiazem Hydrochloride
MICROSPHERES OF DILTIAZEM HYDROCHLORIDE BY IONOTROPIC GELATION TECHNIQUE
... ABSTRACT: Diltiazem hydrochloride is a calcium channel blocker used in various cardiac ...of diltiazem the alginate-chitosan microspheres were prepared by Ionotropic gelation technique and ...The ...
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Preparation and Evaluation of Diltiazem Hydrochloride Controlled Release Matrix Tablets Employing Aegle marmelos Gum: A Novel Natural Controlled Release Polymer
... drug delivery systems that have been explored, oral drug delivery is the most preferred option for systemic delivery of drug via various pharmaceutical products of different dosage forms. The advantage of administering a ...
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Identification, Characterization and Drug-Excipient Compatibility of Diltiazem Hydrochloride by Physico-Chemical Techniques
... of diltiazem hydrochloride with β- cyclodextrin (CD) was investigated by phase ...of Diltiazem HCl and complexing agent ...of diltiazem hydrochloride-βCD in 1:1 and 1:2 ratios were ...
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FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLET OF DILTIAZEM HYDROCHLORIDE BY MELT GRANULATION TECHNOLOGY
... In the present study an attempt has been made to prepare sustained release tablet of Diltiazem hydrochloride using different waxes as release retardant polymer. FTIR study shows compatibility between drug ...
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New Diltiazem Potentiometric Membrane Sensor Stands on Theoretical Calculations as a Useful Device for Diltiazem Hydrochloride Analysis in Pharmaceutical Formulation and Urine
... of diltiazem hydrochloride in pharmaceutical formulation and urine were ...calculation, diltiazem-tetraphenylborate (DTM-TPB) complexes were employed as electroactive material in the ...
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Evaluation of gum damar as a novel microencapsulating material for ibuprofen and diltiazem hydrochloride
... Gum:diltiazem hydrochloride ratio (� ) 1:1 and ( � ) 2:1, affinity of drug towards the GD. Since, GD is a Gum:ibuprofen ratio (�) 1:1 and (�) 2:1. hydrophobic gum, the affinity of ibuprofen perhaps was greater ...
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FORMULATION AND CHARACTERIZATION OF DILTIAZEM HYDROCHLORIDE MATRIX TABLETS BY USING NATURAL POLYMERS
... of diltiazem hydrochloride matrix tablets by using gum karaya and gum kondagogu matrix tablets were developed to be capable to provide prolonged release patterns over ...containing diltiazem ...
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Formulation and Evaluation of Controlled Release Gastro-Retentive In situ Gel for Diltiazem Hydrochloride
... variables were selected sodium alginate (X 1 ) and ratio of polymers HPMC K4M: Gellum Gum (X 2 ) combined concentration of HPMC K4M and Gellum Gum was kept constant i.e. 2% and nine formulations were formulated as per ...
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DEVELOPMENT AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF DILTIAZEM HYDROCHLORIDE
... containing diltiazem hydrochloride for the treatment of hypertension which is use deliver the drug at specific time as per pathophysiological needs of the disease and improvement of therapeutic efficacy and ...
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Formulation and evaluation of diltiazem hydrochloride extented release tablet by melt granulation technique
... Melt granulation (thermoplastic granulation) is a process in which the granulation is obtained through the addition of binder, which melts or softens at relatively low temperature. After melting, a binder acts like a ...
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A Validated Stability Indicating HPLC Method for Determination of Diltiazem Hydrochloride in Tablet Dosage Form
... of Diltiazem hydrochloride transferred to a 50 ml volumetric flask; 40 ml of methanol was added, sonicated for one hour, cooled, diluted with methanol to volume and ...
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Formulation and Evaluation of Diltiazem Hydrochloride Microspheres for Oral Controlled Release Drug Delivery using Poly (ε-Caprolactone)
... Diltiazem hydrochloride is a calcium channel blocker, which is mainly used in the management of angina pectoris. It was used in the present work since it has low bioavailability (30-40%), a dose of 30 mg to ...
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Analytical method development and validation for residual solvent of Diltiazem hydrochloride extended release capsule by Gas chromatography
... chromatographic method for estimation of residual solvents in Diltiazem Hydrochloride Extended Release Capsule drug product. The developed method is specific, precise, linear, accurate, rugged, robust and ...
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Formulation and Development of Diltiazem Hydrochloride Sustained Release Alginate Beads by Ionotropic External Gelation Technique
... 450.98. Diltiazem hydrochloride extended release capsules contain Diltiazem hydrochloride in extended release beads at doses of 120, 180, 240, 300, 360 and 420 mg ...
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Preparation and invitro evaluation of diltiazem hydrochloride microspheres by using eudragit RL100, eudragit RS100 as polymers
... of Diltiazem Hydrochloride with the respective polymers that is Eudragit RL100 and RS100,[9] and physical mixture of main formulation was established by Infrared Absorption Spectral Analysis (FTIR) (Fig ...
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An Expired Non-Toxic Diltiazem Hydrochloride as Corrosion Inhibitor for Cu in Nitric Acid Medium
... of Diltiazem Hydrochloride s offers interesting possibilities for corrosion protection because attendance of its hetero atoms in their molecules, and they are of particular important due to their safe ...
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Formulation and In Vitro Evaluation of Gastro Retentive Delivery of Diltiazem Hydrochloride Using Natural Polymers
... Diltiazem hydrochloride (DTZ) has been used in the management of classical, vasospastic angina pectoris and also in the treatment of essential ...of Diltiazem HCL were successfully formulated by ...
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Design and evaluation of pH sensitive multi-particulate systems for chronotherapeutic delivery of Diltiazem hydrochloride
... Since, diltiazem hydrochloride is a drug, which exhibits a high solubility, it would be possible to minimize drug release from the coated pellets below pH ...
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Formulation Development and Evaluation of Mouth Dissolving Tablets of Diltiazem Hydrochloride by Direct Compression Method
... This is to certify that the dissertation entitled “Formulation Development and Evaluation of Mouth Dissolving Tablets of Diltiazem Hydrochloride by Direct Compression method” submitted by SAJU.R (Reg ...
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Improving the Bioavailability of Diltiazem Hydrochloride by Forming Complexes with β-Cyclodextrin
... Diltiazem hydrochloride (DLT) is a calcium channel blocker used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. Its biological half life is 3 - 4.5 h, which is relatively short ...
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