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disease overlap

A comparison of diagnostic consistency for asthma-chronic obstructive pulmonary disease overlap and clinical characteristics study

A comparison of diagnostic consistency for asthma-chronic obstructive pulmonary disease overlap and clinical characteristics study

... airways disease first, estimate the syndromic diagnosis of asthma, COPD, and ACO; perform spirom- etry testing, and then commence therapy to estimate the therapeutic effect and confirm the diagnosis; additional ...

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Quantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome

Quantitative computed tomography measurements of emphysema for diagnosing asthma-chronic obstructive pulmonary disease overlap syndrome

... There is little evidence on the diagnostic value of quantitative CT measurements of emphysema for ACOS. We hypothesized that quantitative CT measurement of emphy- sema may dete[r] ...

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Decreased serum club cell secretory protein in asthma and chronic obstructive pulmonary disease overlap: a pilot study

Decreased serum club cell secretory protein in asthma and chronic obstructive pulmonary disease overlap: a pilot study

... pulmonary disease (COPD) overlap (ACO), and identification of biomarkers for phenotype recognition will encourage good patient care by providing optimal ...

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Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

... broader disease correlation; alternatively, it could reflect limited sample size or a mix of positive and negative genetic correlations across the genome for the ...

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Childhood lung function predicts adult chronic obstructive pulmonary disease and asthma chronic obstructive pulmonary disease overlap syndrome

Childhood lung function predicts adult chronic obstructive pulmonary disease and asthma chronic obstructive pulmonary disease overlap syndrome

... We estimated the reweighted prevalence of ACOS and COPD alone to be 2.9% and 4.1%, respectively, at 45 years of age. Few studies have attempted to quantify the prevalence of ACOS and it would be expected to vary ...

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Causes of death in patients with asthma and asthma–chronic obstructive pulmonary disease overlap syndrome

Causes of death in patients with asthma and asthma–chronic obstructive pulmonary disease overlap syndrome

... A limitation of this study was that we could not survey all patients with asthma and ACOS. Some asthmatic patients with no or few respiratory symptoms stopped visiting our hospital or changed to another hospital when ...

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EASL Clinical Practice Guidelines: Management of cholestatic liver diseases

EASL Clinical Practice Guidelines: Management of cholestatic liver diseases

... liver disease are at increased risk of osteoporosis is unclear, with contradictory reports in the ...age, disease severity and degree of cholestasis differ- ...liver disease and/or a high degree of ...

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Overlap between age-at-onset and disease-progression determinants in Huntington disease

Overlap between age-at-onset and disease-progression determinants in Huntington disease

... onset, disease progression, and age at death, the only possibility that would allow for a disease duration independent of CAG repeat size 9 would be a dif- ferent neuroanatomical basis for, on the one hand, ...

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Clinical Spectrum and Pulmonary Manifestations of Patients with Anti U1RNP Antibody Status.

Clinical Spectrum and Pulmonary Manifestations of Patients with Anti U1RNP Antibody Status.

... Nuclear antigenic pool that was soluble in normal saline, termed extractable nuclear antigen was used for complement fixation test, as the initial serologic test for MCTD. After the introduction of hemagglutination, ...

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Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort

Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort

... greater disease se- verity and a worse prognosis than patients with non- ACO ...assess disease progression in COPD and the data on the impact of ACO on disease progression as defined by loss of lung ...

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Clinical characteristics of the asthma–COPD overlap syndrome – a systematic review

Clinical characteristics of the asthma–COPD overlap syndrome – a systematic review

... Fourth Korea National Health and Nutrition Examination (KNHANES IV) Survey (2007–2009). They included a population sample of 9,104 noninstitutionalized individuals (.19 years). The subjects completed questionnaires on ...

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Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary candidiasis

Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary candidiasis

... Calculations were carried out using PASW Statistics 20. Frequencies were compared using a chi-square test. Continuous data were compared using the nonpara- metric Wilcoxon rank-sum test or the Fisher’s exact test, where ...

9

Vitamin D deficiency is associated with impaired disease control in asthma–COPD overlap syndrome patients

Vitamin D deficiency is associated with impaired disease control in asthma–COPD overlap syndrome patients

... examinations; disease control and severity was assessed by disease-specific questionnaires (COPD assessment test, asthma control test, and modified Medical Research Council); furthermore, 25(OH)D levels ...

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Differences in the risk of mood disorders in patients with asthma-COPD overlap and in patients with COPD alone: a nationwide population-based retrospective cohort study in Korea

Differences in the risk of mood disorders in patients with asthma-COPD overlap and in patients with COPD alone: a nationwide population-based retrospective cohort study in Korea

... alcohol-related illnesses, epilepsy, cancer, arthritis, Par- kinson’s disease, dementia, obesity, cerebrovascular dis- ease, and atherosclerosis [22]. Concurrent medications were identified based on the ...

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Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis

... We also acknowledge other potential limitations in this study. First, additional GWAS cohorts are not available to replicate our findings. However, we used the largest datasets available at the time of our study to ...

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Overlap in drug-disease associations between clinical practice guidelines and drug structured product label indications

Overlap in drug-disease associations between clinical practice guidelines and drug structured product label indications

... primary disease, (2) for a patient characteristic present with the primary disease, (3) in a specific clinical setting, (4) in combination with another drug for the pri- mary disease, (5) as ...

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Heterogeneity of asthma and COPD overlap

Heterogeneity of asthma and COPD overlap

... There are some limitations to this study. First, we used arbitrary definitions for the four groups, which did not fully meet the common diagnostic criteria. Because we used KNHANES and NHI data, bronchial provocation ...

10

Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey

Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey

... The current study has several strengths. NHANES is a benchmark national health survey and is one of the few population-based surveys that include validated examina- tion measures, biological specimen collection, and ...

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UNIVERSITA DEGLI STUDI DI PARMA

UNIVERSITA DEGLI STUDI DI PARMA

... the disease and probably quantifying the effect of therapeutic ...human disease, and it could represent a valuable tool for drug discovery approach, mimic what is real happen in the ...the disease ...

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Prevalence of different comorbidities in COPD patients by gender and GOLD stage

Prevalence of different comorbidities in COPD patients by gender and GOLD stage

... Results: At least one comorbidity of clinical relevance was found in 78.6 % of patients, but at least two in 68.8 %, and three or more were found in 47.9 % of subjects. Mean CCI was 3.4 ± 1.6sd. The overall prevalence ...

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