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Dissolution enhancement

EFAVIRENZ DISSOLUTION ENHANCEMENT II: AQUEOUS CO SPRAY DRYING

EFAVIRENZ DISSOLUTION ENHANCEMENT II: AQUEOUS CO SPRAY DRYING

... CONCLUSION: The results obtained demonstrate that co-spray-drying is an effective technique in the enhancement of efavirenz dissolution. The formulation was obtained by a water-based process, bringing a ...

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Dissolution enhancement of Meloxicam Using Liquisolid Technique

Dissolution enhancement of Meloxicam Using Liquisolid Technique

... the dissolution enhancement of Meloxicam by Liquisolid ...The dissolution rate of Meloxicam was compared with the marketed ...higher dissolution profile compared to other ...acceptable ...

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Liquisolid tablets for dissolution enhancement of a hypolipidemic drug

Liquisolid tablets for dissolution enhancement of a hypolipidemic drug

... This investigation was aimed to improve the dissolution rate of the poorly soluble drug lovastatin, by formulating it as a liquisolid compact. Different liquisolid compacts were prepared using mathematical ...

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FORMULATION STRATEGY FOR DISSOLUTION ENHANCEMENT OF SIMVASTATIN

FORMULATION STRATEGY FOR DISSOLUTION ENHANCEMENT OF SIMVASTATIN

... The present work aim was “Formulation Strategy for Dissolution Enhancement of Simvastatin”. Simvastatin is lipid lowering drug which is known as HMG CoA reductase. The objective of this study was to ...

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DEVELOPMENT, EVALUATION AND CHARACTERIZATION OF SURFACE SOLID DISPERSION FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF DICLOFENAC

DEVELOPMENT, EVALUATION AND CHARACTERIZATION OF SURFACE SOLID DISPERSION FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF DICLOFENAC

... for enhancement of solubility and dissolution rate as it is a poorly water soluble (BCS-II) ...and dissolution rate of Diclofenac by the preparation of its Surface solid dispersion with using various ...

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Dissolution enhancement of pioglitazone hydrochloride using β- cyclodextrin

Dissolution enhancement of pioglitazone hydrochloride using β- cyclodextrin

... The prepared formulations had shown good Angle of repose, Compressibility Index and Hausner Ratio. Among them F3 had shown better than F2, F1 and Pure. The F3 has shown better dissolution rate than the F2, F1, and ...

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Solubility and Dissolution Enhancement of Meropenem by Nano Suspension Approach

Solubility and Dissolution Enhancement of Meropenem by Nano Suspension Approach

... The dissolution profiles of the pure drug and nanosuspensions are shown in the Figure ...The dissolution efficiency of all the formulations was ...The dissolution efficiency of op- timized ...

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Preparation of solid dispersions of glibenclamide for in-vitro dissolution enhancement

Preparation of solid dispersions of glibenclamide for in-vitro dissolution enhancement

... approximately recorded as 6 fold higher than the pure glibenclamide in the same buffer conducted under same conditions as in dissolution of GLB-SD4. It was also, observed that the GLB-SD4 showed higher in-vitro ...

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 PREPARATION, CHARACTERIZATION AND DISSOLUTION ENHANCEMENT OF DIHYDROARTEMISININ MICROPARTICLES

 PREPARATION, CHARACTERIZATION AND DISSOLUTION ENHANCEMENT OF DIHYDROARTEMISININ MICROPARTICLES

... drug DHA showed poor solubility in aqueous media. Optimum formulation batch D4 with 1:4 w/w drug carrier ratio showed enhancement in solubility i.e. 340 µg/ml solubility in water which was 2.5 times greater than ...

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 STUDIES IN DISSOLUTION ENHANCEMENT OF ATENOLOL USING HP-βCD

 STUDIES IN DISSOLUTION ENHANCEMENT OF ATENOLOL USING HP-βCD

... The dissolution rate of a drug from its dosage form is now considered as an important parameter in ...bioavailability. Dissolution is the rate-limiting step in the absorption of drugs from the solid dosage ...

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FORMULATION OF NICERDIPINE HYDROCHLORIDE INCLUSION COMPLEX FOR DISSOLUTION ENHANCEMENT

FORMULATION OF NICERDIPINE HYDROCHLORIDE INCLUSION COMPLEX FOR DISSOLUTION ENHANCEMENT

... the dissolution rate of poorly soluble Nicardipine hydrochloride with cyclodextrin complexation by using different techniques like physical mixing, solvent evaporation and kneading ...the dissolution rate ...

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SOLUBILITY AND DISSOLUTION ENHANCEMENT OF ACECLOFENAC BY SOLID DISPERSION TECHNIQUE

SOLUBILITY AND DISSOLUTION ENHANCEMENT OF ACECLOFENAC BY SOLID DISPERSION TECHNIQUE

... faster dissolution rate and improved bioavailability of the drug when it is formulating in the form of solid ...solubility, dissolution rate and bioavailability of the ...

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A Study on Solubility and Dissolution Enhancement of Roxithromycin

A Study on Solubility and Dissolution Enhancement of Roxithromycin

... According to recent estimates, nearly 40% of new chemical entities are rejected because of poor solubility i.e. biopharmaceutical properties. Poor Solubility of drug may result in inadequate bioavailability and thus in ...

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BIOAVAILABILITY AND DISSOLUTION ENHANCEMENT OF GLYBURIDE NANOSUSPENSION

BIOAVAILABILITY AND DISSOLUTION ENHANCEMENT OF GLYBURIDE NANOSUSPENSION

... carried in triplicate for 10 h at 37±10°C temperature and 50 rpm. At regular intervals of time, 1 ml of sample from the external medium was taken and replaced with fresh phosphate buffer and all the samples were analyzed ...

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SPHERICAL CRYSTALLIZATION A NOVEL APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF SIMVASTATIN

SPHERICAL CRYSTALLIZATION A NOVEL APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF SIMVASTATIN

... Micronization process gives rise to increased free surface energy and thus poor flowability and compressibility of powders which makes them difficult to use in downstream processing in the pharmaceutical industry such as ...

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Enhancement of Solubility and Dissolution Rate of Lopinavir by Solid Dispersion Technique.

Enhancement of Solubility and Dissolution Rate of Lopinavir by Solid Dispersion Technique.

... solubility enhancement of Embelin in order to enhance its absorption through ...maximum enhancement in the solubility of Embelin as well as % drug release after 2 ...and dissolution profile of ...

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Naproxen-Gelucire Nanoformulations for Improved Solubility and Dissolution Rate of Poorly Water-Soluble Drug Naproxen

Naproxen-Gelucire Nanoformulations for Improved Solubility and Dissolution Rate of Poorly Water-Soluble Drug Naproxen

... and dissolution enhancement using the poorly water soluble drug, ...the dissolution data into various empirical release kinetic models, an attempt to investigate the release mechanism was ...

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ENHANCEMENT SOLUBILITY AND DISSOLUTION OF MEFENAMIC ACID BY MODIFIED STARCH

ENHANCEMENT SOLUBILITY AND DISSOLUTION OF MEFENAMIC ACID BY MODIFIED STARCH

... the dissolution profile of the mefenamic acid by Modified Starch as a ...the dissolution rate of poorly water soluble ...drug. Dissolution rate is the rate determining step in the bioavailability of ...

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Enhancement of Solubility and Dissolution Properties of Lacidipine by Solid Dispersion

Enhancement of Solubility and Dissolution Properties of Lacidipine by Solid Dispersion

... in dissolution profile of lacidipine, a poorly water-soluble ...on dissolution rate and efficiency was more prominent at lower ...and dissolution rate limited absorption and other side effect can be ...

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 DISSOLUTION METHOD DEVELOPMENT AND ENHANCEMENT OF SOLUBILITY OF CLOPIDOGREL BISULFATE

 DISSOLUTION METHOD DEVELOPMENT AND ENHANCEMENT OF SOLUBILITY OF CLOPIDOGREL BISULFATE

... enhancing dissolution. Typically, the greatest enhancement in the dissolution of poorly soluble compounds is made by changing the dissolution medium to increase compound ...vitro ...

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