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dopamine D1/D2 receptor

Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance

Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance

... BDNF receptor TrkB has been recently reported to be involved in the control of the size of the striatum by modulating the number of medium spiny neurons (MSNs), with deletion of the gene for the TrkB ...

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Sensitivity to Dopamine D1/D2 Receptor Stimulation in Mice Lacking Connexin-32 or Connexin-36

Sensitivity to Dopamine D1/D2 Receptor Stimulation in Mice Lacking Connexin-32 or Connexin-36

... combined D1/D2 ...intact D1/D2 synergism? For several reasons, that conclusion cannot be drawn from the present ...of D1/D2 synergism is always manifested by a significant ...

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THE INHIBITORY EFFECT OF ASCORBIC ACID ON APOMORPHINE-INDUCED LICKING BEHAVIOR IS MEDIATED BY DOPAMINE D2 RECEPTOR MECHANISMS IN RAT

THE INHIBITORY EFFECT OF ASCORBIC ACID ON APOMORPHINE-INDUCED LICKING BEHAVIOR IS MEDIATED BY DOPAMINE D2 RECEPTOR MECHANISMS IN RAT

... in dopamine receptor function has been ...mixed dopamine D1/D2 receptor agonist; apomorphine in ...the dopamine D1 receptor antagonist SCH 23390 or the ...

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The Role of Connexin36 in Dopamine D1/D2 Synergism and its Breakdown in Transgenic Mice

The Role of Connexin36 in Dopamine D1/D2 Synergism and its Breakdown in Transgenic Mice

... of D1/D2 receptor synergism? One could hypothesize very different mechanisms depending on whether D1 and D2 receptors are located on the same neuron or on distinct ...of D1 and ...

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Dopamine D1-D5 receptor protein immunohistochemistry in dog pial arteries

Dopamine D1-D5 receptor protein immunohistochemistry in dog pial arteries

... anti-dopamine D1 receptor protein antibody alone (a) or pre-adsorbed with the corresponding blocking peptide ...anti-dopamine D2 receptor antibody alone (c) or pre- adsorbed with ...

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Methamphetamine-induced changes in the striatal dopamine pathway in μ-opioid receptor knockout mice

Methamphetamine-induced changes in the striatal dopamine pathway in μ-opioid receptor knockout mice

... of dopamine receptors in the stria- tum: D1 and ...express dopamine D1 receptors whereas most striatopallidal neu- rons express dopamine D2 receptors ...of dopamine ...

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Single exposure of dopamine D1 antagonist prevents and D2 antagonist attenuates methylphenidate effect

Single exposure of dopamine D1 antagonist prevents and D2 antagonist attenuates methylphenidate effect

... of D1 or D2 DA receptors by single treatment of selective DA antagonist given prior to a single (acute) or following repetitive (chronic) MPD exposure would prevent the acute and/or the chronic MPD effects ...

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Nest box exploration may stimulate breeding physiology and alter mRNA expression in the medial preoptic area of female European starlings

Nest box exploration may stimulate breeding physiology and alter mRNA expression in the medial preoptic area of female European starlings

... neither D1 nor D2 correlated with ER α or ER β mRNA expression in the mPOA, and past studies in rats show that estradiol alters ratios of D1 and D2 receptors in the mPOA by elevating D2 ...

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Dopamine D1  and D2 Receptors in Immunostimulation under Activation of Mu Opioid Receptors in Mice with Different Psychoemotional States

Dopamine D1 and D2 Receptors in Immunostimulation under Activation of Mu Opioid Receptors in Mice with Different Psychoemotional States

... their highly specific antagonists SCH-23390 [R(+)- 7-hloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro- 1H-3-benzazepinehydrochloride] (Sigma, Germany) and haloperidol (Gedeon Richter A.O., Hungary) respectively were ...

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Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?

Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?

... in dopamine metabolism and neurotransmission: tyrosine hydroxylase (TH); DOPA decarboxylase (DDC); catechol-O-methyl transferase (COMT); dopamine transporter 1 (SLC6A3); dopamine receptor ...

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Relationship between calorie intake, physical activity, and dopamine D2 receptor Taq1A gene polymorphism in normal-weight, overweight, and obese students of the faculty of medicine of university of Sumatera Utara

Relationship between calorie intake, physical activity, and dopamine D2 receptor Taq1A gene polymorphism in normal-weight, overweight, and obese students of the faculty of medicine of university of Sumatera Utara

... with D2 dopamine receptor gene polymorphism present lower amounts of dopamine ...the dopamine system causes addictive, impulsive, and compulsive behavior which causes someone not being ...

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Hypothesizing “Reward” Gene Polymorphisms May Predict High Rates of Injury and Addiction in the Workforce: A Nutrient and Electrotherapeutic Based Solution

Hypothesizing “Reward” Gene Polymorphisms May Predict High Rates of Injury and Addiction in the Workforce: A Nutrient and Electrotherapeutic Based Solution

... risk, addiction-prone individuals, are Electrotherapeutic Device(s) and Programs. We further propose patented KB220Z, a nutraceutical designed to release dopamine at the nucleus accum- bens, will reduce craving ...

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Dopamine D2 receptor functional selectivity as a mechanism of atypical antipsychotic drug action

Dopamine D2 receptor functional selectivity as a mechanism of atypical antipsychotic drug action

... of receptor stimulus”, “biased agonism”, “protean agonism”, “differential engagement”, and “stimulus trafficking”, to name just a ...of receptor pharmacology, and therefore will be used throughout the ...

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Once-Monthly Subcutaneously Administered Risperidone in the Treatment of Schizophrenia: Patient Considerations

<p>Once-Monthly Subcutaneously Administered Risperidone in the Treatment of Schizophrenia: Patient Considerations</p>

... Population pharmacokinetics and prediction of dopamine D2 receptor occupancy after multiple doses of RBP-7000, a new sustained-release formulation of risperidone, in schizophrenia patien[r] ...

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The expression profile of Dopamine D2 receptor, MGMT and VEGF in different histological subtypes of pituitary adenomas: a study of 197 cases and indications for the medical therapy

The expression profile of Dopamine D2 receptor, MGMT and VEGF in different histological subtypes of pituitary adenomas: a study of 197 cases and indications for the medical therapy

... to dopamine agonists; Most PAs exist low expression of MGMT and high expres- sion of VEGF, TMZ or bevacizumab treatment could be applied under the premise of ...

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Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study

Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study

... Opioid receptor genes, specifically OPRM1, and methadone metabolism genes, including ABCB1 and CYP450, are among the most commonly studied genes to date ...

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Regulation of Akt and Wnt signalling by the dopamine D2 receptor and metabotropic glutamate receptor 2/3

Regulation of Akt and Wnt signalling by the dopamine D2 receptor and metabotropic glutamate receptor 2/3

... Wnt proteins are secreted glycoproteins that bind to Frizzled (Fz) receptors and the co-receptor low-density lipoprotein receptor-related protein 5/6 (LRP5/6). This event can activate one or more of the 3 ...

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Differential regulation of renal phospholipase C isoforms by catecholamines

Differential regulation of renal phospholipase C isoforms by catecholamines

... whereas dopamine produces a natriuresis, NE has an antinatriuretic ...a D1 agonist, or pramipexole, a D1/D2 agonist, intravenously or infused fenoldopam or NE into the renal artery of ...

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Evaluating Population Origins and Interpretations of Identity: a Case Study of the Lemba of South Africa

Evaluating Population Origins and Interpretations of Identity: a Case Study of the Lemba of South Africa

... The dopamine transporter, DAT-1, is localized to the synapses of all dopaminergic neurons of ...because dopamine is not efficiently packaged or subsequently released into the synaptic ...of dopamine, ...

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The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

... Total RNA was extracted from cultured NCI-H292 cells after 48 h treatment with dopamine (1 μM), A68930 (1 μM), isoproterenol (1 μM), or CSE (10%) using the RNeasy Mini Kit (QIAGEN, Valencia, CA). Total RNA was ...

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