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Dose Combination

Spillover adherence effects of fixed-dose combination HIV therapy

Spillover adherence effects of fixed-dose combination HIV therapy

... Triangle Park, NC (abacavir sulfate 600 mg + lamivudine 300 mg; FDC group) versus NRTI combinations taken as two separate pills (NRTI Combo group) using data from a national sample of 30 health plans covering ...

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Fixed dose combination therapy for the prevention of atherosclerotic cardiovascular diseases

Fixed dose combination therapy for the prevention of atherosclerotic cardiovascular diseases

... fixed-dose combination therapy is expected to be better than with multiple tablets, but it has been argued that they will likely have a greater potential for adverse effects than be- havioural or lifestyle ...

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Capillary electrophoresis for the assay of fixed dose combination tablets of artesunate and amodiaquine

Capillary electrophoresis for the assay of fixed dose combination tablets of artesunate and amodiaquine

... Fixed-dose combination (FDC) formulations are strongly preferred and recommended over blistered co-packaged or loose tablets combinations to promote adherence to treatment ...

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MONTELUKAST AND LEVOCETERIZINE FIXED DOSE COMBINATION-AN EVIDENCE REVIEW

MONTELUKAST AND LEVOCETERIZINE FIXED DOSE COMBINATION-AN EVIDENCE REVIEW

... Fixed dose combination can be defined as a single dosage form which includes two or three active pharmaceutical ingredients, manufactured and distributed in fixed ...fixed dose combination ...

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RATIONALITY OF THE FIXED DOSE COMBINATION OF TELMISARTAN AND AMLODIPINE IN MANAGEMENT OF MILD TO MODERATE HYPERTENSION UNRESPONSIVE TO LOW DOSE MONOTHERAPY

RATIONALITY OF THE FIXED DOSE COMBINATION OF TELMISARTAN AND AMLODIPINE IN MANAGEMENT OF MILD TO MODERATE HYPERTENSION UNRESPONSIVE TO LOW DOSE MONOTHERAPY

... compare combination therapy of telmisartan 40 mg with amlodipine 5 mg once daily versus high dose monotherapy (telmisartan 80 mg daily and amlodipine 5 mg daily as individual ...that combination ...

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Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO<sup>&reg;</sup> (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

... fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two random- ized, ...

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FORMULATION AND EVALUATION OF FIXED DOSE COMBINATION PRODUCTS OF ANTITUBERCULAR DRUG

FORMULATION AND EVALUATION OF FIXED DOSE COMBINATION PRODUCTS OF ANTITUBERCULAR DRUG

... Objective of the present study is to formulate and evaluate fixed dose combination tablets of Rifampicin and Isoniazid. The granules of Rifampicin and Isoniazid were prepared separately by wet granulation, ...

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Study on Fixed Dose Combination (Polypill) for CVD Prevention

Study on Fixed Dose Combination (Polypill) for CVD Prevention

... fixed dose combination(polypill) medication The reasons for treatment gaps are complex and likely to include resistance (on the part of both physicians and patients) to the cost, complexity and ...

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Simultaneous Determination of Linezolid and Levamisole Hydrochloride in a Fixed Dose Combination

Simultaneous Determination of Linezolid and Levamisole Hydrochloride in a Fixed Dose Combination

... by MRSA, it is postulated that combining an antibiotic and immune stimulant as a single unit dosage form to treat MRSA infection can become a novel therapeutic approach. To formulate a fixed dose ...

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Amlodipine and valsartan as components of a rational and effective fixed-dose combination

Amlodipine and valsartan as components of a rational and effective fixed-dose combination

... The increasing popularity of fi xed-dose combinations in the treatment of hypertension is justifi ed. Co-administering two antihypertensive agents with complementary mechanisms of action enables a better blood ...

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Management of dyslipidemia and hyperglycemia with a fixed-dose combination of sitagliptin and simvastatin

Management of dyslipidemia and hyperglycemia with a fixed-dose combination of sitagliptin and simvastatin

... Fixed-dose combination (FDC) therapies have been shown to improve adherence by reducing pill burden, the complexity of treatment regimen, and, potentially, ...

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Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes

Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes

... There are now five therapeutic classes of drugs available to be used for glycemic control in patients with T2DM; biguanides (eg, metformin), insulin secretagogues (eg, sulfonylureas), thiazolidinediones, alpha ...

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Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

... Fixed-dose combination analgesics with two or more agents may offer additive or synergistic benefits to treat the multiple mechanisms of ...fixed-dose combination analgesic product combines ...

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REVIEW ON THE FIXED DOSE COMBINATION DRUGS AND THEIR INCOMPATIBILITIES

REVIEW ON THE FIXED DOSE COMBINATION DRUGS AND THEIR INCOMPATIBILITIES

... Fixed dose combination provides challenge in product development due to incompatibility of two ...fixed dose combinations, to find remedies that overcome the problems in designing formulation and to ...

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THE CRAVE OF  FIXED DOSE COMBINATION IN INDIAN MARKET

THE CRAVE OF FIXED DOSE COMBINATION IN INDIAN MARKET

... fixed-dose combination (FDC) in Indian market as per the Indian ...A combination drug most commonly refers to an FDC, which is a formulation including two or more active pharmaceutical ingredients ...

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Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice

Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice

... blood pressure (BP) not adequately controlled with antihypertensive monotherapy or as first-line therapy in patients at high risk. Blockers of the renin–angiotensin system, being the foundation of antihypertensive ...

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SIMULTANEOUS ESTIMATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN FIXED DOSE COMBINATION IN UV SPECTROPHOTOMETRY

SIMULTANEOUS ESTIMATION OF VALSARTAN AND HYDROCHLOROTHIAZIDE IN FIXED DOSE COMBINATION IN UV SPECTROPHOTOMETRY

... Valsartan (VAL) and Hydrochlorothiazide (HTZ) are used in combination in treatment of Hypertension. Two simple, accurate, precise, economical and reproducible UV spectrophotometric methods have been developed for ...

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 FIXED DOSE COMBINATION AND DISEASE MANAGEMENT

 FIXED DOSE COMBINATION AND DISEASE MANAGEMENT

... Rational drug therapy means the use of the right medicine in the right manner (dose, route, frequency of administration, duration of therapy, etc.) in the right patient at the right cost and at the right time. ...

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Efficacy of tiotropium&ndash;olodaterol fixed-dose combination in COPD

Efficacy of tiotropium&ndash;olodaterol fixed-dose combination in COPD

... et al used clinical data from more than 23,000 patients to compare the effects of four LABA/LAMA FDCs with monocomponents. They demonstrated that TIO/OLO 5/5 µ g increased trough FEV 1 by 55 mL (95% CI 46–64) compared to ...

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Fixed dose combination products as Oro-dispersible tablets: A review

Fixed dose combination products as Oro-dispersible tablets: A review

... the combination rule as described in FDA’s guidance for development of FDC and co- packaged drug products as well as in 21CFR ...the combination is safe and effective for a significant patient population ...

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