Drug-resin complex
Design, Optimization and Evaluation of Chewable Tablets of Clarithromycin using Ion Exchange Resins
... The drug-resin complex loading process was optimized for the content of resin, activation, swelling time, stirring time, influence of pH and temperature for maximum drug loading and was ...
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INCREASING COMPLEX FORMATION OF WEAK ACID DRUG WITH ION EXCHANGE RESIN
... molecules, drug can be loaded into resin by exchanging with counter ion of IER and hence, drug resin complex (DRC) is ...The drug is released from DRC by exchanging with ions in ...
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ION EXCHANGE RESIN AS A POTENTIAL TECHNOLOGY ON FOR TASTE MASKING: A REVIEW
... bitter drug weak cation exchange resin or weak anion exchange resin are used where it is depend upon the nature of the drug used for the ...the drug resin complex formed ...
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Ion exchange resins as drug delivery carriers
... as drug carriers in pharmaceutical dosage forms for controlled release formulation ...active drug is accomplished by providing a semi-permeable coating around discrete, minute, ion exchange resin ...
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“A Review on Ion Exchange Resins as Drug Delivery System” by Kiran D. Belsare, Suparna S. Bakhle, Kanchan P. Upadhye, Gouri R. Dixit, Ninad A Mahakulkar, India.
... preparing drug–resonates, the actual capacity obtainable under specific experimental conditions would depend upon the accessibility of the functional groups for the drug of ...the drug physicochemical ...
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“Formulation, Characterization and Evaluation of Taste Masked Rapid Disintegrating Tablet of Ofloxacin by Ion Exchange Resin Technique” by Shailendra P. Kela, Disha Kesharwani, India.
... oral drug delivery systems preferably is the use of ion exchange resins as ...the drug molecule and the oral mucosal ...particle, drug substance can be prevented from going into solution and ...
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FORMULATION AND EVALUATION OF TASTE MASKED ORAL SUSPENSION OF CHLOROQUINE PHOSPHATE
... exchange resin and to formulate oral suspension of the taste masked ...of drug resin ...masked drug resin complex (DRC). Optimization of drug loading was carried ...the ...
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Variable cavity volume tooling for high performance resin infusion moulding
... the resin so as to induce a local high-pressure gradient at positions remote from the injection ...the resin, thus increasing infu- sion ...higher resin flowrates, thus prevent- ing the formation of ...
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Empirical modeling of the fine particle fraction for carrier-based pulmonary delivery formulations
... powder dispatchment tube, SetA, SetD), flow rate (L/min) during the experiment, were included according to data found in the articles. The complete structure of the database is shown in Table 1 and the full database is ...
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“PREDICTION OF DRUG-IN-RAT PERMEABILITY AS A FUNCTION OF SELECTED DRUG MOLECULAR PROPERTIES” by Kamal I. Al-Malah, Saudi Arabia.
... first drug-like filter proposed to predict oral bioavailability of compounds that have achieved phase II clinical status 1,2 ...World Drug Index (WDI) ...
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A probiotic complex, rosavin, zinc, and prebiotics ameliorate intestinal inflammation in an acute colitis mouse model
... probiotic complex or the combina- tion drug; the latter exerted the greatest effect on coli- tis (p < ...combination drug, the HT-29 cell line, a human colorectal adenocarci- noma cell line, was ...
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Drug resinates an attractive approach of solubility enhancement of atorvastatin calcium
... indicating partial amorphous nature of the resin. DSC thermogram of 1:1 proportion of AD (fig. 2) showed the absence of an endotherm at 149.4° corresponding to the melting of ATV. The broad endotherm at 243.3°, ...
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Preparation and characterization of tetrandrine-phospholipid complex loaded lipid nanocapsules as potential oral carriers
... lipid-based drug delivery systems: one is the drug solubility within the lipidic system, and the other is the physiological processing of lipid carriers to achieve the desirable drug ...
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Taste Masking and Molecular Properties of Metformin Hydrochloride-Indion 234 Complexes
... of drug complexes. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug to resin, and ...temperature. ...
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Formulation Development and Evaluation of Diltiazem Hydrochloride Oral Disintegrating Tablets
... of drug resin cross linking is done with parameters 1:4 as drug resin concentration ratio, stirring time 6hrs which showed ...96.06% drug loading on to ...high resin: drug ...
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A mathematical model for targeting chemicals to tissues by exploiting complex degradation
... active drug clearance tends to reduce its concentration in the tissue is intuitively ...maximum drug concentra- tion may occur at a point intermediate between the cen- tre and the edge of the ...active ...
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A REVIEW ON PENETRATION ENHANCER FOR SEMISOLIDS
... of drug application both for local and systemic effect Semisolids dosage forms usually are intended for localized drug ...various drug candidates who’s per oral bioavailability is ...novel ...
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DRUG LOADING AND RELEASE PROPERTIES OF IONEXCHANGE RESIN COMPLEXES WHICH PREPARED BY BATCH PROCESS
... the resin and the ionic drug due to shielding and competitive binding ...oral drug delivery since the resin can carry the drug and release it in the gastrointestinal (GI) tract due to ...
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The Paradigm-Shift toward the Next Generation of Drugs
... Specialized, reductionist, and linear approaches are extensively used in medical and pharmaceutical research. Reductionist systems understand the mechanisms of many diseases and the receptors involved in pathogenic ...
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Analysis of MWCNT/epoxy composites at microwave frequency: reproducibility investigation
... Carbon nanotubes (CNTs) and, in particular, multi- walled CNTs (MWCNTs) have been used intensively as a filler in a variety of polymers [1,2]. Their outstanding mechanical, electrical, and thermal properties allow then ...
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