Duck hepatitis B virus
A novel transcriptional element in circular DNA monomers of the duck hepatitis B virus.
... We report the presence of two elements, pet and net, that are required for proper transcription of the duck hepatitis B virus (DHBV). These regions were previously identified by using plasmid ...
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Signals for Bidirectional Nucleocytoplasmic Transport in the Duck Hepatitis B Virus Capsid Protein
... the duck hepatitis B virus (DHBV) animal model, as this system also allows us to study hepadnavirus infection of cultured primary ...of hepatitis B virus, the human ...
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Translation of Duck Hepatitis B Virus Reverse Transcriptase by Ribosomal Shunting
... The organization of the duck hepatitis B virus (DHBV) pgRNA is shown in Fig. 1. It has an 118-nucleotide-long 5⬘ leader that contains a stable RNA stem-loop (ε, ⌬G ⫽ ⫺10.4 kcal/mol [1]) which ...
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Recombinant Duck Interferon Gamma Inhibits Duck Hepatitis B Virus Replication in Primary Hepatocytes
... human hepatitis B virus (HBV), the woodchuck hepatitis virus (WHV), and the duck hepatitis B virus ...DHBV-infected duck could be a useful model, ...
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Elimination of Duck Hepatitis B Virus RNA-Containing Capsids in Duck Interferon-Alpha-Treated Hepatocytes
... I duck interferon (DuIFN) cDNA encodes a homologue of mammalian interferon-alpha (IFN- a ...of duck hepatitis B virus (DHBV) replication in primary hepatocytes in order to determine the ...
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Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymerase.
... To assist in the assignment of these functions to domains of the duck hepatitis B virus polymerase protein, we have constructed a series of substitution mutations and a large insertion m[r] ...
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Cellular Receptor Traffic Is Essential for Productive Duck Hepatitis B Virus Infection
... of duck hepatitis B virus (DHBV) entry into susceptible primary duck hepatocytes (PDHs), using mutants of carboxypeptidase D (gp180), a transmembrane protein shown to act as the primary ...
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Duck Hepatitis B Virus Replication in Primary Bile Duct Epithelial Cells
... of duck hepatitis B virus ...in duck liver tissue sections and in primary cultures of total duck liver ...Normal duck serum in the growth medium was found to be essential ...
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Proteomic analysis of primary duck hepatocytes infected with duck hepatitis B virus
... DHBV: Duck hepatitis B virus; DAPI: 4',6'-diamidino-2-phenylindole; DTT: dithiothre- itol; FBS: fetal bovine serum; GAPDH: glyceraldehyde-3- phosphate dehydrogenase; HBV: hepatitis ...
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Protective Efficacy of DNA Vaccines against Duck Hepatitis B Virus Infection
... the duck hepatitis B virus (DHBV) pre-S/S and S proteins were tested in Pekin ...following virus challenge, significant differences in the rate of virus removal from the ...
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Glucagon Treatment Interferes with an Early Step of Duck Hepatitis B Virus Infection
... the duck hepatitis B virus (DHBV) ...after virus uptake resulted in a dose-dependent reduction in the levels of intra- and extracellular viral gene products and of secreted ...the ...
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Cloned duck hepatitis B virus DNA is infectious in Pekin ducks.
... Representative DHBV isolates Isolate DHBV 111-2 DHBV 111-13 DHBV IV-25 DHBV 111-14 DHBV IV-45 DHBV IV-33 DHBV IV-13 DHBV 111-25 DHBV VIII-2 DHBV VIII-35 DHBV VI-92 DHBV VI-95 Origin of S[r] ...
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Humoral immune responsiveness in duck hepatitis B virus-infected ducks.
... The presence of autoantibody in a small percentage of the DHBV-infected ducks examined here and its absence in the uninfected ducks tested raises the possibility that DHBV Downloaded fro[r] ...
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Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry
... DHBV preferentially binds to detergent-soluble domains on hepatocellular membranes. We have previously shown that endocytic internalization of DHBV requires an unusually long time period (9, 10) and diverges from that of ...
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Biochemical and immunological characterization of the duck hepatitis B virus envelope proteins.
... In serum, the pre-S proteins were shown to exist predominantly in DHBV-DNA-free particles associated with a 17-kilodalton protein which, by N-terminal amino acid sequence analysis, was s[r] ...
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Duck hepatitis B virus replicates in the yolk sac of developing embryos.
... We detected the supercoiled form of DHBV DNA, DHBV RNA transcripts similar to those in the virus-replicating liver, and DNA polymerase activity and viral DNA in corelike particles in ext[r] ...
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Integrated structures of duck hepatitis B virus DNA in hepatocellular carcinoma.
... Among four hepadnaviruses, various structures of integrated viral DNA in hepatocellular carcinoma have been reported for human hepatitis B 3, 4, 6, 10, 17, 22, 24, 29, 31 and woodchuck h[r] ...
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Characterization of the major duck hepatitis B virus core particle protein.
... DHBcAg polypeptide exhibits heterogeneity in SDS-PAGE that can be completely removed following treatment of native core particles with alkaline phosphatase Fig.. 3, suggesting that the p[r] ...
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Regulatory sequences of duck hepatitis B virus C gene transcription.
... The 3' end of the C gene promoter region was defined by transfection of liver and nonliver cells with plasmids containing the coding region for CAT as a reporter gene and DHBV DNA fragme[r] ...
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Initiation and termination of duck hepatitis B virus DNA synthesis during virus maturation.
... To map the termination sites of minus-strand DNA synthesis, virion DNA was digested with AccI and 5' end labeled at the AccI sites, one not RESULTS Evidence that protein is linked to the[r] ...
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