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early age-related macular degeneration

Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study

Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study

... in the measured macular sensitivity where the average dB (logarithmic attenuation) changed from 25.0 dB at start to 26.1 dB at 6 months and 25.76 at 12 months. This was better than the placebo group that had an ...

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Identification of lncRNAs involved in biological regulation in early age-related macular degeneration

Identification of lncRNAs involved in biological regulation in early age-related macular degeneration

... LncRNAs demonstrate important effects and participate in different biological processes. AMD is a multifactorial disease and might also be associated with the dysregula- tion of lncRNAs. The primary purpose of this study ...

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Retinal and choroidal thickness in early age-related macular degeneration

Retinal and choroidal thickness in early age-related macular degeneration

... increasing age both in aged patients classified as clinically normal and in those with all stages of AMD, but it was particularly prevalent in those with advanced ...

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The effect of pre-adapting light intensity on dark adaptation in early age-related macular degeneration

The effect of pre-adapting light intensity on dark adaptation in early age-related macular degeneration

... Age-related macular degeneration (AMD) is a degenerative disease of the central retina that typically presents in patients over 50 years of ...the early stage of the disease, which ...

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Age-related macular degeneration: a target for nanotechnology derived medicines

Age-related macular degeneration: a target for nanotechnology derived medicines

... Abstract: Despite the fact that the retina is a fairly accessible portion of the central nervous system, there are virtually no treatments for early age-related macular degeneration ...

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Risks of age related macular degeneration and led lighting

Risks of age related macular degeneration and led lighting

... quite early. The paper dwells on how age-related macular degeneration evolves and on a part which eye age pigment plays in the ...for age pigment accumulation and ...

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A comparison of contrast sensitivity in early mild and early intermediate age-related macular degeneration after adjusting for age and visual acuity

A comparison of contrast sensitivity in early mild and early intermediate age-related macular degeneration after adjusting for age and visual acuity

... in age-related macular degeneration especially in its early stages separately, and results analyzing contrast sensitivity in AMD patients are ...with early intermediate ...with ...

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Radiation therapy for neovascular age-related macular degeneration

Radiation therapy for neovascular age-related macular degeneration

... (wet) age-related macular degeneration (neovascular ...too early to conclude on the safety and efficacy of epimacular brachytherapy and stereotactic radiosurgery, preliminary results ...

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Quantitative Assessment of Foveal Avascular Zone in Patients with Early and Intermediate Nonexudative Age Related Macular Degeneration Using Optical Coherence Tomography Angiography

Quantitative Assessment of Foveal Avascular Zone in Patients with Early and Intermediate Nonexudative Age Related Macular Degeneration Using Optical Coherence Tomography Angiography

... were age ≥ 55 years old, drusen and/or retinal pigment epithelium (RPE) abnormalities (hyper-/hypopigmenta- tion) secondary to AMD, a spherical equivalent of ≥ −3D to ≤ ...and age-matched control group of ...

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Transcriptome changes in age-related macular degeneration

Transcriptome changes in age-related macular degeneration

... Age-related macular degeneration (AMD) is a debilitating, common cause of visual impairment. While the last decade has seen great progress in understanding the pathophysiology of AMD, the ...

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Targeted therapy in age-related macular degeneration (AMD)

Targeted therapy in age-related macular degeneration (AMD)

... to age-related macular degeneration (AMD), but the results of these studies are still controversial and ...in early 2020 conducted a meta-analysis of studies that examined IL-8 gene ...

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Age-related macular degeneration: experimental and emerging treatments

Age-related macular degeneration: experimental and emerging treatments

... With the recent addition of the OCT to the confocal SLO, cross-sectional images can be obtained giving information on deep retinal structures. Its applications include the ability to image early transit phases to ...

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The Role of Diet, Micronutrients and the Gut Microbiota in Age-Related Macular Degeneration: New Perspectives from the Gut-Retina Axis

The Role of Diet, Micronutrients and the Gut Microbiota in Age-Related Macular Degeneration: New Perspectives from the Gut-Retina Axis

... AREDS1 indicated that 80 mg of zinc oxide, alone or in combination with antioxidants, significantly reduced the risk of progression to advanced AMD. AREDS2 showed that a low dose of zinc (25 mg) instead of a high dose ...

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Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration

Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration

... of early detection and treatment of neovascular AMD (no effective treatment yet exists for the nonneovascular form of the ...for early AMD ...for early detection of CNV, ranging from Amsler chart ...

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Cone photoreceptor macular function and recovery after photostress in early non-exudative age-related macular degeneration

Cone photoreceptor macular function and recovery after photostress in early non-exudative age-related macular degeneration

... serve as a relevant clinical trial endpoint. Foveal cone func- tion and recovery after photostress allows such testing to be performed quickly to facilitate high throughput models. Our results show that the use of a ...

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Dobesilate for dry age related macular degeneration

Dobesilate for dry age related macular degeneration

... Clinically and histologically, AMD is generally classi- fied into two major subtypes: dry or non-exudative AMD, of which GA is a severe form, and wet or exudative AMD. Wet AMD is very debilitating and often develops ...

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Recent developments in the treatment of age related macular degeneration

Recent developments in the treatment of age related macular degeneration

... Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrialized countries ...improved early diagnosis as well as disease monitoring during ...

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Early and intermediate age-related macular degeneration: update and clinical review

Early and intermediate age-related macular degeneration: update and clinical review

... on early stages of AMD, which can be of the interest of clinicians involved in the care of elderly ...of early and intermediate stages of AMD, together with algorithms for the diagnosis and management of ...

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Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

... AMD: Age-related macular degeneration; CBD: Corticobasal degeneration; CSF: Cerebrospinal fluid; DLB: Dementia with Lewy bodies; EOAD: Early-onset Alzheimer ’ s disease; ETDRS: ...

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Stereotactic radiotherapy for wet age-related macular degeneration: current perspectives

Stereotactic radiotherapy for wet age-related macular degeneration: current perspectives

... The Macular Epiretinal Brachytherapy in Treated Age-related Macular Degeneration (MERITAGE) study was an international, multicenter, prospective, inter- ventional, non-controlled ...

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