Endothelial Nitric Oxide Synthase
Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function
... Abstract—An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular ...in endothelial responses to both smoking and n-3 FA in ...
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Shear stress effect on endothelial nitric oxide synthase in cultured human umbilical vein endothelial cells
... various endothelial phenotypes exhib- iting inflammatory responses, many of which reflect al- ternations in certain contamination protein expression levels ...of endothelial nitric oxide ...
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Serum Nitric Oxide Level and Endothelial Nitric Oxide Synthase Gene INTRON4 VNTR Polymorphism in Essential Hypertension.
... of endothelial nitric oxide synthase ...neuronal nitric oxide synthase (nNOS/ NOS1), another constitutive enzyme, is responsible for its ...Inducible nitric ...
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Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs
... from l -arginine by the action of the enzyme endothelial nitric oxide synthase (eNOS) (11, 12). NO diffuses from the endo- thelial cell into the smooth muscle cell, activates guanylate cy- ...
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Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate gene association study
... the endothelial nitric oxide synthase gene (NOS3), located at the 7q35-q36 region, has emerged as a logical candidate gene in the development of ...
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Immunohistochemical localization of endothelial nitric oxide synthase in endometrial tissue of women with unexplained infertility
... of endothelial nitric oxide synthase in stroma, glandular epithelium and vascular endothelium of endometrial tissues of women with unexplained infertility, but changes in expression of enzyme ...
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Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
... Endothelial nitric oxide synthase (eNOS) is activated by phosphorylation of serine 1177 by the protein kinase ...aortic endothelial cells, hyperglycemia inhibited eNOS activity 67%, and ...
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A vascular bed–specific pathway regulates cardiac expression of endothelial nitric oxide synthase
... The endothelial nitric oxide synthase (eNOS) gene is induced by a variety of extracellular signals under both in vitro and in vivo ...murine endothelial progenitor cells, the 1,600-bp ...
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Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice
... The vasculoprotective effects of sex hormones, particularly estrogens, have been attributed to their ability to increase the bioavailability of nitric oxide through activation of endothelial ...
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Hypotension and reduced nitric oxide elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase
... Nitric oxide (NO), constitutively produced by endothelial nitric oxide synthase (eNOS), plays a major role in the regulation of blood pressure and vascular ...the ...
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Endothelial Nitric Oxide Synthase (eNOS) 4a/b and G894T Polymorphisms and Susceptibility to Preeclampsia
... of nitric oxide (NO) is produced from L-arginine by endothelial nitric oxide synthase ...regulates endothelial function and is an important factor in the mainte- nance of ...
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Computational Prediction of the Effects of Single Nucleotide Polymorphisms of the Gene Encoding Human Endothelial Nitric Oxide Synthase
... impaired nitric oxide (NO) pathway is involved in endothelial dysfunction and coronary artery disease (CAD) ...(1). Endothelial nitric oxide synthase (eNOS) is an enzyme ...
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Role of Endothelial Nitric Oxide Synthase Gene Polymorphisms (Glu298Asp) in Egyptian Patients with Recurrent Spontaneous Abortion
... Figure 1: A 2% agarose gel showing digestion of polymerase chain reaction products of exon seven of the endothelial nitric oxide synthase gene with SAU3AI for detection of the different ...
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Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen
... rulline during acute incubations, using methods reported previ- ously (21). This procedure provides a direct evaluation of the acute activation of existing eNOS, keeping signal transduction mecha- nisms intact (27). ...
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Endothelial nitric oxide synthase G894T polymorphism increases the risk of infertility in women with endometriosis
... The eNOS G894T gene polymorphism has been associated with endometriosis at any stage (Zervou et al., 2003), at advanced stages (Kim et al., 2009) and enhances vascular response to phenylephrine (Philip et al., 1999). ...
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Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase
... serum–treated endothelial cells and also inhibited the caveolin upregulation induced by HC serum ...of endothelial cells exposed to high cholesterol ...in endothelial cells exposed to high ...
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A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer
... miRNAs, which differentiates the mesenchymal subtype from the other tumors. Similarly, we obtained a specific immune response in the classified human mesenchymal tumors. In particular, a significant increase of dendritic ...
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Arginase Inhibition Restores Peroxynitrite Induced Endothelial Dysfunction via L Arginine Dependent Endothelial Nitric Oxide Synthase Phosphorylation
... lial nitric oxide (NO) is an important vasoprotective molecule contributing to endothelial functions, and impaired NO signal- ing associated with endothelial dysfunction is now regarded as an ...
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Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity
... Regulation of Nitric Oxide Synthesis by Proinflammatory Cytokines in Human Umbilical Vein Endothelial Cells Elevations in Tetrahydrobiopterin Levels Enhance Endothelial Nitric Oxide Synt[r] ...
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Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE deficient mice
... Nitric oxide (NO) derived from endothelial NO synthase (eNOS) is regarded as a protective factor against atherosclerosis. Therefore, augmentation of eNOS expression or NO production by phar- ...
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