Endothelial progenitor cells and endothelial function
The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD
... from manufacturer). Furthermore, studies that investi- gated the protective effect of statins found that oxLDL-induced EPC dysfunction and senescence were profoundly inhibited by 1 μ M atorvastatin, which may occur via ...
7
Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia
... circulatory EPC concentration was investigated among the DPP4-deficiency and WT animals with and without CLI induction. The results of this study contradict our hypoth- esis that adult male DPP4-deficient rats have a ...
17
Obesity suppresses circulating level and function of endothelial progenitor cells and heart function
... and endothelial and vascular dysfunction has been extensively discussed recently ...aortic endothelial repair ability after LPS-induced endothelial damage was found to be notably reduced in obese ...
12
Impaired function of endothelial progenitor cells in children with primary systemic vasculitis
... between endothelial damage and repair capacity for children with ...into endothelial dysfunction and moving forward could allow us to explore the prognostic relevance of this approach in individual patients ...
10
Endothelial progenitor cells as biomarkers for cardiovascular risk
... 116 training compared to best medical treatment only. Remarkably, increased walking capacity increased further six months after supervised exercise training cessation suggesting an ongoing benefit of the intervention. ...
160
Metformin improves circulating endothelial cells and endothelial progenitor cells in type 1 diabetes: MERIT study
... improved endothelial function in dia- betes [29, ...improve endothelial function in type 1 diabetes, we hypothesised that metformin modulates cEPCs and cECs count and this cardio-protective ...
10
Circulating endothelial progenitor cells: a new approach to anti aging medicine?
... numerous cells, but primarily macro- phages, TNF-alpha is known to inhibit proliferation of repair cells in the body, such as oligodendrocytes in the brain [95], and suppress activity of endogenous stem ...
12
Angiogenic Function of Prostacyclin Biosynthesis in Human Endothelial Progenitor Cells
... stem cells 䡲 angiogenesis 䡲 prostaglandins 䡲 peroxisome proliferator–activated receptor 䡲 cyclooxygenase E vidence continues to accumulate on the existence of circulating endothelial progenitor ...
9
Endothelial progenitor cells: a new player in lupus?
... identify cells originating from a myeloid lineage have been ...hematopoietic cells Th e most widely used marker to identify immaturity is C34 ...stem cells; however, the exact origin and signals for ...
10
Obstructive sleep apnea and endothelial progenitor cells
... or function of EPCs include prolonged inflammation response, oxidative stress, increased sympathetic activation, physiological adaptive responses of tissue to hypoxia, reduced EPC mobilization, EPC apopto- sis, ...
14
Endothelial progenitor cells inhibit platelet function in a P selectin dependent manner
... platelet function, via up-regulation of cyclooxygenase (COX)-2 and pros- tacyclin (PGI 2 )-dependent inhibition of platelet activa- tion, aggregation, adhesion, and thrombus formation ...platelet function ...
11
Endothelial progenitor cells and burn injury – exploring the relationship
... Future considerations: standardization of clinical assays and patient selection The biggest impediment to conducting effective research on the role of CACs as a biomarker for burn severity is the lack of consensus with ...
7
Effects of androgens on endothelial progenitor cells in vitro and in vivo
... debated. Endothelial progenitor cells are bone marrow-derived cells involved in endothelial healing and angiogenesis, which promote cardiovascular ...of endothelial ...
30
B lymphocyte stimulator modulates number and function of endothelial progenitor cells in systemic lupus erythematosus
... Evaluation of BLyS receptors on EPC and EA.hy926 cell surface After pre-incubation with an FcR-blocking reagent, cells were labeled for 30 min on ice with mAb anti-BAFF-R FITC, anti-BCMA PE, and anti TACI APC ...
11
Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy
... Liver function was monitored by Ala- nine amino transferase (ALT), aspertate amino- transferase (AST) and γ-glutamyl- transferase (GGT) were ...+ endothelial progenitor cells, 30 ...
13
Endothelial progenitor cells: Potential novel therapeutics for ischaemic stroke
... cardiac function in a porcine model of acute myocardial infarction ...attenuate endothelial dysfunction and promote cerebral angiogenesis and vasculogenesis which collectively diminish infarct volume and ...
47
Neurotrophic support by traumatized muscle-derived multipotent progenitor cells: Role of endothelial cells and Vascular Endothelial Growth Factor-A
... upon culture with cellulose fiber-concentrated CM [55], and it is possible that concentrating CM in future studies may yield stronger neural support. To promote better DRG attachment and growth on NF substrate, laminin ...
11
Endothelial progenitor cells and neural progenitor cells synergistically protect cerebral endothelial cells from Hypoxia/reoxygenation-induced injury via activating the PI3K/Akt pathway
... Fig. 4 EPCs and NPCs improved the angiogenic function of H/R-injured ECs via activating the PI3K pathway. a, representative plots of tube formation. Scale bar: 200 μ m. b, summarized data of EC tube formation, ...
12
Expanded endothelial progenitor cells mitigate lung injury in septic mice
... A recent study evaluated the efficacy of expanded and non-expanded EPCs in modulating myocardial function [22]. The authors observed that both expanded and non- expanded EPCs improved cardiac function. ...
8
Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD)
... In summary, we present the first data on EPC mobili- zation and proliferation in sepsis with acute impairment of renal function. Acute renal dysfunction, via increasing serum concentrations of endogenous toxins, ...
10