eosinophilic inflammation
Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways
... controlling the resolution of eosinophilic inflammation are poorly understood. In the present study, we demonstrate that lung eosinophils obtained by bronchoalveolar lavage (BAL) after aerosol allergen ...
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Perception of bronchial obstruction in asthmatic patients Relationship with bronchial eosinophilic inflammation and epithelial damage and effect of corticosteroid treatment
... of eosinophilic inflammation in airway ...to eosinophilic inflammation and to epithelial damage in airways and that corticosteroid treatment is associated with improved perception of ...
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Periostin levels and eosinophilic inflammation in poorly-controlled asthma
... We have recently shown that blood eosinophil counts are a suitable surrogate for sputum eosinophil propor- tion in identifying patients with eosinophilic asthma, be- ing simple and readily available and thus may ...
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Elevated expression of IL-17RB and ST2 on myeloid dendritic cells is associated with a Th2-skewed eosinophilic inflammation in nasal polyps
... Th2-skewed eosinophilic inflammation in the nasal sinus ...the eosinophilic airway diseases such as allergic asthma, allergic rhinitis and NP [37, ...
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Eosinophilic airway inflammation in COPD
... COPD therapies have limited efficacy. It is likely that identification of specific inflammatory phenotypes may reveal subgroups of patients who are particularly susceptible to targeted therapy. New treatments ...
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Associations of airway inflammation and responsiveness markers in non asthmatic subjects at start of apprenticeship
... We found eosinophilic inflammation to be strongly associated with personal atopy. This is meaningful because atopy is not used to build groups with MCA and hierarchical classifications, whereas FENO, ...
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New drugs targeting Th2 lymphocytes in asthma
... some inflammation still persists in the airways of patients with asthma who have poor airway function, despite reg- ular and prolonged treatment with high doses of inhaled or systemic glucocorticoids ...of ...
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Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma
... In this study, we found eosinophilic inflammation in CA and CVA, and for the first time in the newly- described asthmatic condition of CTVA sputum eosino- philia. Thus these three types of asthma conditions ...
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Chronic eosinophilic pneumonia: A case report and review of the literature
... monary eosinophilic inflammation with unknown eti- ology, characterized by history of allergic disease, cough, sputum, but often breathlessness and wheezing; eosinophil in peripheral blood and/or sputum ...
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Are atopy and eosinophilic bronchial inflammation associated with relapsing forms of chronic rhinosinusitis with nasal polyps?
... and eosinophilic inflammation. Local inflammation of the upper respiratory tract seems to contribute to the maintenance of inflammation at the level of lower air- ...of eosinophilic ...
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Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation
... Adoptively transferred Th1 and Th2 cells modulate expression of adhesion molecules in the lung. To determine whether transfer of Th cells resulted in changes in adhesion-mol- ecule expression, we analyzed expression of ...
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Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease
... to inflammation that promotes airway obstruction; approximately a third of stable COPD patients have evidence of eosinophilic ...targeting eosinophilic inflammation are available or in ...
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Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma
... Methods: CD4 + CD45RB low cells, as Tm, were obtained by magnetic-activated cell sorting and flow cytometry from the spleens of BALB/c mice with ovalbumin (OVA)-induced asthma. Tm were cocultured with hydrocortisone ...
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Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation
... Among the factors shown to contribute to airway eosinophilia, blood eosinophils came first when performing a multiple logistic regression. There are few studies assessing the ability of blood eosinophils to identify ...
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Eosinophilic disorders of the gastro-intestinal tract: an update
... Regarding the role of inhalant allergens in development of EoE, the data in favor of their involvement are certain. In a study of Yamazaki et al. mononuclear cells from 25 patients with EoE were incubated with inhalant ...
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Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction
... Stomach and small bowel mucosal biopsies were normal. Colonoscopic mucosal biopsies revealed severe patchy mucosal eosinophilia with eosinophil degranulation and cryptitis, affecting the entire colon. Eosinophils were ...
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Inflammation-associated microbiota in pediatric eosinophilic esophagitis
... Background: Eosinophilic esophagitis (EoE) is an allergic disorder characterized by eosinophil-predominant esophageal inflammation, which can be ameliorated by food antigen ...esophageal ...
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Eosinophilic esophagitis
... Eosinophils are typically present throughout the gas- trointestinal tract since it is continuously exposed to foods, environmental allergens, toxins, and pathogens. Interestingly, in healthy individuals, the esophagus is ...
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Eosinophilic esophagitis
... Eosinophils are typically present throughout the gastrointestinal tract since it is continuously exposed to foods, environmental allergens, toxins, and pathogens. Interestingly, in healthy individuals, the esophagus is ...
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Blood eosinophil count as a prognostic biomarker in COPD
... the eosinophilic cutoff, patients with eosinophilic COPD exhibited no specific characteristic in terms of symptoms, lung function, exacerbation rate, and prognosis, thereby suggesting that the association ...
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