Eph-receptor
Identification of the Eph receptor pathway as a novel target for eicosapentaenoic acid (EPA) modification of gene expression in human colon adenocarcinoma cells (HT-29)
... to Eph receptor B4 (ab70404), rab- bit monoclonal to Vav2 (ab52640), rabbit polyclonal to Eph receptor B4 (ab64820) and rabbit polyclonal to beta actin (ab8227) were all purchased from ...
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Drosophila Eph receptor guides specific axon branches of mushroom body neurons
... Vertebrate Eph RTKs and their Ephrin ligands have been shown to play roles in many aspects of axon guidance, including midline crossing at the optic chiasm, retinotopic map formation and motoneuron innervation of ...
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The VAB 1 Eph receptor tyrosine kinase and SAX 3/Robo neuronal receptors function together during C elegans embryonic morphogenesis
... We report that the VAB-1 Eph RTK shows a dosage- dependent genetic interaction with the conserved axon guidance receptor, SAX-3/Robo. The Roundabout (Robo) family of receptors are evolutionary conserved and ...
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Schaupp, Andreas (2012): Eph receptor clustering is the central integrator in eliciting graded Kinase-dependent signaling responses. Dissertation, LMU München: Fakultät für Biologie
... to Eph receptor and interestingly enough act on it in a rather inhibitory mode by opposing cluster internalization or promoting cell spreading rather than collapse ...passive Eph receptor ...
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Eph Receptor Clustering by Chondroitin Sulfate Inhibits Axon Regeneration
... or receptor-type protein-tyrosine phosphatase zeta (PTP/RPTPβ) family, which consists of both transmembrane and soluble secreted forms, is expressed predominantly in the CNS and is found in neurons and astrocytes ...
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Simultaneous targeting of Eph receptors in glioblastoma
... The Eph family of receptors is amenable to the development of targeted therapies [27, ...The Eph receptor A3 was upregulated in tumorspheres of established G48a GBM cells and also in never-passaged ...
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MicroRNA 302b negatively regulates IL 1β production in response to MSU crystals by targeting IRAK4 and EphA2
... interleukin-1 receptor-associated kinase 4 (IRAK4) and Eph receptor A2 (EphA2) were the hot targets of ...the Eph receptor tyrosine kinase (RTK) family and regulates inflammation and ...
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Eph/ephrin interactions modulate muscle satellite cell motility and patterning
... only Eph receptor specific for ephrin-A1 ...signaling receptor for ephrin-A1 in many systems (for a review, see Pasquale, ...specific Eph/ephrin interactions, the actual signaling complex ...
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Investigating the role of ephrins and their receptors in mouse folliculogenesis and ovulation
... which Eph-ephrin signaling has been studied, the main roles of Eph receptors and ephrins are to mediate adhesive and repulsive responses in order to control cell ...positioning. Eph-ephrin signaling ...
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Vasculogenic mimicry is associated with trastuzumab resistance of HER2 positive breast cancer
... its receptor induces Tzm resistance mediated by the nuclear translocation of SMAD2/3 molecules through in- duction of the epithelial-mesenchymal transition (EMT) and/or stemness in cancer cells [9, ...
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Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord
... A survey of members of the B-type Eph receptor family in the mouse ventral spinal cord (Fig. 1a) indicated that spinal progenitors co-express several EphB receptors, as well as EphA4, as shown by in situ ...
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Coordinated Eph-ephrin signaling guides migration and axon targeting in the avian auditory system
... cating Eph receptor forward signaling in normal devel- ...of Eph receptor signaling are ne- cessary for migration of auditory nuclei precursor cells during development and that in turn, ...
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Paradoxes of the EphB1 receptor in malignant brain tumors
... of receptor tyrosine kinases. Eph receptor-mediated forward and ephrin ligand- mediated reverse signalings are termed bidirectional ...that Eph/ephrin signaling regulates cell migration, ...
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Eph/ephrin signalling during development
... development. Eph receptors lie functionally at the interface between pattern formation and ...morphogenesis. Eph receptors constitute the largest family of receptor tyrosine kinases ...Hence, ...
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EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population
... and Eph receptors might affect monocyte chemotaxis, contributing to the development of ...the Eph/ephrin molecule is important for the developing cardiovascular system, as shown by the presence of heart and ...
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Cell Signalling in Limb Development and Hindbrain Segmentation
... the receptor operates in the hindbrain, the progress zone and during tendon development may help to define the function of Cek-8, f^A-receptor activation requires binding by membrane-associated ligands ...
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Effective Parameters in Contact Mechanic for Micro/nano Particle Manipulation Based on Atomic Force Microscopy
... Figure 9(a) shows different simulations of indentation depth versus force for two spherical cells of EpH and C3T3, based on the Hertz contact theory. As is indicated by the figure, for the same applied force, the ...
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Eph/ephrins and N cadherin coordinate to control the pattern of sympathetic ganglia
... N-Cadherin is expressed by neural crest cells segregating into discrete sympathetic ganglia Based on extensive evidence for cadherin regulation as a mechanism that mediates cell aggregation in embryogenesis (Radice et ...
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Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum
... its receptor, following a strict mutually exclusive expression pattern, they will segregate into two adjacent distinct compartments, similar to hindbrain rhombomeres, for example ...the receptor but differ ...
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EphB6 null mutation results in compromised T cell function
... surface receptor tyrosine ...(1). Eph kinases are classified into A and B subfamilies according to the sequence homology; the former has 9 members (EphA1–9) (1), and the latter, 6 members (EphB1–6) ...14 ...
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