Establishing the nomenclature of penicillin-binding proteins
Characterization of nutritionally variant streptococci by biochemical tests and penicillin binding proteins
... A comparative study of 60 strains of nutritionally variant streptococci (NVS) with 34 strains of Streptococcus mitis and 37 strains of Streptococcus sanguis Il showed the presence of a r[r] ...
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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials.
... “miraculous” penicillin antibiotic that inactivates these ...of penicillin and its wide utilization in medicine in the 1940s, several new classes and generations of related β-lactam antibiotics have been ...
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Whole genome sequencing of penicillin resistant Streptococcus pneumoniae reveals mutations in penicillin binding proteins and in a putative iron permease
... to penicillin in ...to penicillin, the introduction of altered versions of PBPs into a penicillin-susceptible strain by sequential transformation led to strains with a minimal increase in resistance, ...
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Establishing RNA binding proteins as key components of Alzheimer's disease pathophysiology
... There are four core stress activated kinases that phosphorylate eIF2α: Protein Kinase R (PKR), PKR-like/Pancreatic endoplasmic reticulum kinase (PERK), Heme- Regulated Inhibitor (HRI), or General Control ...
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Eliminating a Set of four penicillin binding proteins triggers the Rcs phosphorelay and Cpx stress responses in escherichia coli
... Penicillin binding proteins (PBPs) are responsible for synthesizing and modifying the bacterial cell wall, and in Escherichia coli the loss of several nonessential low-molecular-weight PBPs gives ...
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Analysis of amino acid motif of penicillin binding proteins 1a, 2b, and 2x in invasive Streptococcus pneumoniae nonsusceptible to penicillin isolated from pediatric patients in Casablanca, Morocco
... genes, suggesting a high frequency recombination or point mutations that they undergoes over the time [21]. Conclusions This study constitutes the first investigation of pbp gene alterations in invasive S. pneumoniae ...
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Characterization of the Bacillus subtilis Penicillin Binding Protein PBP4
... a Penicillin Binding Protein belonging to the class C of AmpH type whose function remains poorly ...N-terminal penicillin-binding domain have been produced in Escherichia coli and ...
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Penicillin binding protein inactivation by human neutrophil myeloperoxidase
... (penicillin-binding proteins, PBPs) found in all eubacteria, that covalently bind beta-lactam antibiotics to their active sites with loss of enzymatic ...of penicillin binding by PBPs, ...
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Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in beta-lactam sensitivity of Listeria monocytogenes
... In conclusion then, the construction of PBP mutant strains ΔPBP4 and ΔLmo441 (Fig. 2) displayed no obvi- ous growth defects in L. monocytogenes, suggesting that the individual PBPs are most likely not essential for ...
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Single nucleotide polymorphisms in genes encoding penicillin binding proteins in β lactamase negative ampicillin resistant Haemophilus influenzae in Japan
... the penicillin-binding proteins, and we reconfirmed that susceptibility to β-lactam antibiotics was mainly defined by previously reported SNPs in the ftsI ...
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The 2.4-A crystal structure of the penicillin-resistant penicillin-binding protein PBP5fm from Enterococcus faecium in complex with benzylpenicillin.
... Abstract. Penicillin-binding proteins (PBPs) are mem- brane proteins involved in the final stages of peptidogly- can synthesis and represent the targets of b-lactam an- ...
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Variation in penicillin binding protein patterns of penicillin resistant clinical isolates of pneumococci
... These two resistant strains had a common PBP pattern that was completely different from the PBP pattern of the penicillin-susceptible laboratory strain in the number of PBPs detectable b[r] ...
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An updated nomenclature for keratin-associated proteins (KAPs)
... This nomenclature preserves the widely used and broadly referred to system proposed by Rogers and Powell [10], but with the important addition of a species identifier to constitute an informative KAP naming system ...
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Oxygen-Binding Proteins
... Changes Induced by O 2 Binding • O 2 binding rearranges electrons within Fe +2 making it more compact so that it fits snugly within the plane of porphyrin. • Since Fe is bound to histidine of the globin ...
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Prediction of DNA-Binding Proteins and their Binding Sites
... DNA-binding proteins play an important role in various essential biological processes such as DNA replication, recombination, repair, gene transcription, and ...DNA-binding proteins and the ...
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CaMELS : In silicoprediction of calmodulin binding proteins and their binding sites
... ) binding protein that is highly conserved across all ...by binding various targets in the cell including a large number of enzymes, ion channels and other ...CaM binding proteins are mostly ...
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GraphProt: modeling binding preferences of RNA binding proteins
... Abbreviations APR, average precision; AUROC, area under the receiver operating characteristic curve; CDS, coding sequence; CLIP, cross-linking and immunoprecipitation; dsRBP, double-stranded RNA-binding protein; ...
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Development of an Immunochromatographic Strip for Simple Detection of Penicillin-Binding Protein 2′
... Laboratory for Antimicrobial Agents, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan, 1 and Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, ...
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Nomenclature. Nomenclature. Acronyms
... and Puigjaner L., 1999e, "Monitoring and fault diagnosis of batch processes using a neuro-fuzzy approach", 8th Mediterranean Congress of Chemical Engineering, November 10-12, 19[r] ...
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Ligand binding and homology modelling of insect odorant-binding proteins
... competitive binding assays using N-phenyl-1-naphthylamine as a fluorescence probe are used to study the ligand binding affinity to OBPs (Lescop et ...the binding affinities in connection with ...
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