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Evidence from clinical studies

Recommended Methods for the Collection of Health State Utility Value Evidence in Clinical Studies

Recommended Methods for the Collection of Health State Utility Value Evidence in Clinical Studies

... While clinical trials can provide an opportunity to collect the required evidence, their appropriateness should be reviewed against the requirements of the model structure taking into account population ...

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Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis

Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis

... published clinical data does not support the hypothesis that there is a qualitative interaction between treat- ment and severity associated with anti-inflammatory or other agents used to treat severe ...sepsis. ...

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Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

... Other studies have reported that various species of Prosopis genus showed considerable anti-inflammatory ...extract from the bark of this plant significantly reduced inflammation in vivo [ 115 ...into ...

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Lessons Learned from Clinical Studies on Infant Nutrition

Lessons Learned from Clinical Studies on Infant Nutrition

... material. Studies that assessed the relationship between infant size or growth during the first 2 years and leading causes of diseases in adulthood were ...Nineteen studies relating to 10 outcomes were ...

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Prolactinomas : clinical studies

Prolactinomas : clinical studies

... The present data indicate that female patients with microprolactinomas experience impaired quality of life, most likely in mental functioning, due to increased anxiety and depression. The cross-sectional study design did ...

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Inflammatory diarrhea due to enteroaggregative Escherichia coli: evidence from clinical and mice model studies

Inflammatory diarrhea due to enteroaggregative Escherichia coli: evidence from clinical and mice model studies

... Six weeks old male BALB/C mice were used in the study and were provided with sterilized water and food before and during the experiment. All the animals were kept in the germ-free environment. Twenty mice were inoculated ...

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Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies

Clinical significance of ALDH2 rs671 polymorphism in esophageal cancer: evidence from 31 case-control studies

... data from the different studies by approxi- mately measuring alcohol intake levels as non-/rare drinking, light drinking, and heavy ...pooled from different studies, which significantly ...

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How To Understand The Evidence From A Clinical Trial

How To Understand The Evidence From A Clinical Trial

... On the other hand, the absolute risk reduction or NNT, since it is dependent on baseline risk, is not meaningful on its own and it requires additional information about the baseline risk for which it is has been ...

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Are pedophiles treatable? Evidence from North American studies

Are pedophiles treatable? Evidence from North American studies

... I will follow that practice. Attempts to change sexual orientation (which was restricted to attempts to chan- ge homosexual men into heterosexuals) all but ce- ased in most Western countries sometime in the 1960 and ...

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Evidence for the Selective Reporting of Analyses and Discrepancies in Clinical Trials: A Systematic Review of Cohort Studies of Clinical Trials

Evidence for the Selective Reporting of Analyses and Discrepancies in Clinical Trials: A Systematic Review of Cohort Studies of Clinical Trials

... What Do These Findings Mean? These findings indicate that discrepancies in analyses between publications and other study documents such as protocols in trial registries are common. The reasons for these discrepancies in ...

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Towards evidence-based computational statistics: lessons from clinical research on the role and design of real-data benchmark studies

Towards evidence-based computational statistics: lessons from clinical research on the role and design of real-data benchmark studies

... patients from a clinical trial if the outcome of interest is the result of a 24 h urine ...emerging from a benchmark study, as exclusion criteria do to the results of clinical tri- ...

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Clinical and epidemiological studies from a tuberculosis referral center in The Netherlands

Clinical and epidemiological studies from a tuberculosis referral center in The Netherlands

... retrieved from the patient ...the clinical criteria of TB, defined as signs, symptoms and/or radiological findings consistent with active ...on clinical and radiological ...histological ...

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Prevention of pertussis: from clinical trials to Real World Evidence

Prevention of pertussis: from clinical trials to Real World Evidence

... efficacy studies have directly compared the aP vaccines most commonly administered today, such as the hexavalent, pentavalent and quadrivalent vaccines, for ...obtain evidence from studies ...

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Hospital performance and clinical leadership: New evidence from Iran

Hospital performance and clinical leadership: New evidence from Iran

... While studies across each of these five areas are mounting in number, there are noticeable gaps that ...on clinical leadership from health systems beyond the US and Europe is largely ...data ...

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The prognosis of allocentric and egocentric neglect : evidence from clinical scans

The prognosis of allocentric and egocentric neglect : evidence from clinical scans

... these studies clearly suggest significant relationships between the location of brain damage and the recovery of neglect post-stroke, none of these reports takes into account the heterogeneity of neglect deficits ...

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Evidence from clinical practice to support healthcare decision making

Evidence from clinical practice to support healthcare decision making

... restriction or matching) and adjustment using statistical techniques (e.g. stratification or multivariable techniques).167 Two methods have been applied in this thesis. In chapter 3, the effect of cytoreductive ...

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Evidence based medicine: Classifying the evidence from clinical trials – the need to consider other dimensions

Evidence based medicine: Classifying the evidence from clinical trials – the need to consider other dimensions

... between evidence and ‘the unknowable’ truth in the context of the limitations of randomized controlled ...observational studies, on the other hand, carry much uncertainty about causality but do describe the ...

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Trade and Institutions: Evidence from Regional Studies

Trade and Institutions: Evidence from Regional Studies

... Figure 1: Trade Structure by Regions (1960-2010) Sluggish economic activity in developed economies accounted for most of the slow down in international trade (See table 1). In 2012, european imports of goods shrank by ...

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Management of vertigo: from evidence to clinical practice

Management of vertigo: from evidence to clinical practice

... branch from the anterior in- ferior cerebellar artery ...the clinical examination is concerned the vestibule-ocular reflex (VOR) is normal unless the peripheral vestibular system is involved (infarct in the ...

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ELECTROENCEPHALOGRAPHIC STUDIES OF PATIENTS HAVING POLIOMYELITIS WITH NO CLINICAL EVIDENCE OF ENCEPHALITIC INVOLVEMENT

ELECTROENCEPHALOGRAPHIC STUDIES OF PATIENTS HAVING POLIOMYELITIS WITH NO CLINICAL EVIDENCE OF ENCEPHALITIC INVOLVEMENT

... electroencephalographic studies of children having measles with no clinical evidence of involvement of the central nervous system.. revealed that 74 of 189 patients had con- siderable ab[r] ...

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