evolution of virulence
Cooperation, quorum sensing, and evolution of virulence in Staphylococcus aureus
... anything that influences the relative fitness of cooperation and/or cheating will also influence the evolution of virulence. Theory predicts that the strain diversity within hosts can have two major ...
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Exploring the Evolution of Virulence Factors through Bioinformatic Data Mining
... molecular evolution of virulence factors is a central theme in our understanding of bacterial pathogenesis and host-microbe ...the evolution of important virulence factor families and the ...
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On the Evolution of Virulence
... equilibria, where two strains always have frequency 0 and the population con- sists of uninfected hosts and hosts infected by the third strain only. There is also one unstable interior equilbrium with all three strains ...
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Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen streptococcus suis
... Protein secretion and secreted proteins. In the publication by Chen et al. describing the genomes of two Chinese S. suis isolates [7], they presented possible virulence-associated factors or pathways in S. suis, ...
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Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli
... express virulence factors — molecules directly involved in pathogenesis but ancillary to normal metabolic func- ...these virulence factors disrupts the normal host physiology and elicits ...processes, ...
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Genome sequence of a recently emerged, highly transmissible, multi antibiotic and antiseptic resistant variant of methicillin resistant Staphylococcus aureus, sequence type 239 (TW)
... 16. Holden, M. T. G., E. J. Feil, J. A. Lindsay, S. J. Peacock, N. P. J. Day, M. C. Enright, T. J. Foster, C. E. Moore, L. Hurst, R. Atkin, A. Barron, N. Bason, S. D. Bentley, C. Chillingworth, T. Chillingworth, C. ...
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Mammalian cell entry genes in Streptomyces may provide clues to the evolution of bacterial virulence
... the evolution of virulence is key to appreciating the role specific loci play in ...in virulence towards amoebae (Acanthamoeba polyphaga) and reduced colonization of plant (Arabidopsis) models, ...
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Mammalian cell entry genes in Streptomyces may provide clues to the evolution of bacterial virulence
... the evolution of virulence is key to appreciating the role specific loci play in ...in virulence towards amoebae (Acanthamoeba polyphaga) and reduced colonization of plant (Arabidopsis) models, ...
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Molecular and virulence characterization of highly prevalent Streptococcus agalactiae circulated in bovine dairy herds
... of virulence characteristics were associated with these highly prevalent STs, the molecular and virulence characterization of 116 strains isolated from bovine, human, fish and environment were ...the ...
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Serum iron uptake and virulence in Staphylococcus aureus
... 2.3.16 S. aureus strain Newman is an efficient producer of siderophores From the mouse infection models, it was apparent that inactivation of sbn and sfa had minimal impact on the virulence of this strain compared ...
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Directed Evolution of an Influenza Reporter Virus To Restore Replication and Virulence and Enhance Noninvasive Bioluminescence Imaging in Mice
... Expected mechanisms of attenuation can be reduced or eliminated during initial construction by incorporating a compensatory enhancement. Inserting an additional transcriptional unit into the Sendai virus genome ...
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Joint Transcriptional Control of Virulence and Resistance to Antibiotic and Environmental Stress in Acinetobacter baumannii
... Mutations in gig genes produce decreased antibiotic resis- tance. As discussed above, several genes required for growth in G. mellonella appeared to be involved in resistance to environ- mental stress and/or antibiotics ...
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Genomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens
... Streptococci colonize a diverse range of animals and tissues, and this association is normally harmless. Occa- sionally some strains of streptococci have an increased ability to cause disease that is often associated ...
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SuhB Is a Regulator of Multiple Virulence Genes and Essential for Pathogenesis of Pseudomonas aeruginosa
... Besides environmental stresses, the host environment under chronic infections might also provide signals that turn off the T3SS while turning on biofilm formation (24). In P. aeruginosa, a global posttranscriptional ...
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Evolution of Replication Efficiency following Infection with a Molecularly Cloned Feline Immunodeficiency Virus of Low Virulence
... Data presented to date suggest that infection of adherent cell lines such as CrFK requires an interaction between the viral envelope glycoprotein and CXCR4 6, 11, 42 and heparan sulfate [r] ...
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Extensive inter-strain diversity among clinical isolates of Shigella flexneri with reference to its serotype, virulence traits and plasmid incompatibility types, a study from south India over a 6-year period
... with transmission of the blaNDM-1 gene for carbapenem resistance [39], though we did not document either fos- fomycin or carbapenem resistance. The incompatibility groups IncIγ, FII, and FIIS are predicted to be associ- ...
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Abiotic environmental variation drives virulence evolution in a fish host parasite geographic mosaic
... seven parasite strains Gill, Host, Maga, Obse, Reiv, Scad and Torm in experiment 5.... Parasite origin * Fish origin.[r] ...
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Remodeling of the Intestinal Brush Border Underlies Adhesion and Virulence of an Enteric Pathogen
... depolymerizes actin filaments and effaces microvilli (16), prior to infection. Cytochalasin pretreatment slightly decreased the adher- ence of the VopV⫹, VopVnR, and VopVnC strains, all of which FIG 1 Schematic structure ...
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Complete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen <em>Brucella melitensis 16M</em>
... classical virulence factors like pili, fimbriae, or virulence plasmids, secreted proteases, exotoxins, endotoxins, and secretary systems like class I, class II, class III, and class ...These ...
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Differential Expression and Roles of Staphylococcus aureus Virulence Determinants during Colonization and Disease
... reus virulence determinants in two clinical isolates during three stages of infection: nasal colonization, early bacteremia, and in- fected heart tissue (thromboembolic lesions) in a sepsis ...
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