Ewing sarcoma of bone
Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow
... advanced Ewing sarcoma patients with fatal outcome irrespective of therapy whereas advanced Ewing sarcoma patients with multiple bone metastases but without BM involvement may be cured ...
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Bone Tumor Environment as a Potential Therapeutic Target in Ewing Sarcoma
... and Ewing sarcoma preclinical models with promising results, especially in osteosarcoma ...sensitive Ewing Sarcoma cell lines and prevent tumor development has already been demonstrated in ...
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The Evaluation of Osteosarcoma and Ewing Sarcoma by Bone Markers in Children and Adult after Chemotherapy
... in Ewing sarcoma, the largest studies of chemotherapy for bone sarcomas are in the pediatric ...and Ewing sarcoma have peak incidences in the pediatric and young adult population, but ...
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High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastases
... Ewing sarcoma (ES) develops in bones or soft tissues of children and ...of bone metastases is one of the most adverse prognostic factors, yet the mechanisms governing their formation remain ...to ...
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Rare adrenal gland incidentaloma: an unusual Ewing’s sarcoma family of tumor presentation and literature review
... 43. DuBois SG, Krailo MD, Gebhardt MC, Donaldson SS, Marcus KJ, Dormans J, Shamberger RC, Sailer S, Nicholas RW, Healey JH, et al. Comparative Evaluation of Local Control Strategies in Localized Ewing ...
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The clinical use of biomarkers as prognostic factors in Ewing sarcoma
... Ewing sarcoma is the second most common primary bone ...the Ewing Sarcoma Family of Tumours (ESFT) and includes Ewing sarcoma of bone, extra-oss- eous Ewing ...
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Small-area analyses of bone cancer diagnosed in Great Britain provide clues to aetiology
... with Ewing sarcoma include both pesticides and zoonotic infectious agents ...as Ewing sarcoma did not ex- hibit space-time clustering ...of Ewing sarcoma is associated with ...
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Localized Ewing sarcoma of the tibia
... to bone and exhibits radiological appearances suggestive of a benign lesion, such as fibrous dysplasia or a simple cyst of bone ...marked bone de- struction and there was little or no periosteal ...
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Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials
... or Ewing sarcoma and altering these regimens or increasing their dose intensity has not improved overall survival (OS) for these groups in > 25 ...other bone sarcomas, have not seen improvement in ...
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The first European interdisciplinary Ewing sarcoma research summit
... that bone development and the involved cytokines in zebrafish are highly homologous to mammals and they could, therefore, be particularly useful for studying bone ...
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Ewing Sarcoma of the Posterior Fossa in an Adolescent Girl
... Histologically, the tumor consisted of small to ovoid cells with scanty cytoplasm. Nuclei were round and hyper- chromatic. The cells were arranged in large sheets (Fig- ures 2(a) and 2(b)) with focal necrosis. Tumor ...
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Ewing sarcoma of the adrenal gland: a case report and review of the literature
... Ewing sarcoma/primitive neuroectodermal tumors (ES/ PNET) was first described in 1921 as a family of tumors characterized by small round cell proliferation and char- acteristic translocation ...common ...
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Ewing sarcoma of the mandible mimicking an odontogenic abscess – a case report
... In the presented case a resection with intraoperative histological control of the soft tissue margins and primary reconstruction of the mandible with a micro- vascular fibular free flap was performed. On the one hand, ...
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Precision medicine approaches for the management of Ewing sarcoma: current perspectives
... sification Ewing sarcoma family of tumors (ESFT) represents a significant percentage of bone sarcomas mainly effecting the pediatric and adolescent population with a mild predominance in the male ...
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<p>Management of recurrent Ewing sarcoma: challenges and approaches</p>
... Ewing sarcoma is a high-grade sarcoma arising in bone or soft tissue and occurs most commonly in adolescent and young adult patients. The primary tumor is treated with surgery and/or ...
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<p>Management of Ewing Sarcoma Family of Tumors: A Short Description of a Rare Primitive Uterine pPNET and Literature Review</p>
... Interestingly, the peak incidence of primary bone ES correlates with the increased levels of the IGF ligands in puberty. Starting from 1990, different preclinical trials demonstrated that IGF1 is expressed in ES ...
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Biomarkers for Bone Tumors: Discovery from Genomics and Proteomics Studies and Their Challenges
... on Ewing sarcoma in relation to the search for biomarkers (Table ...for Ewing sarcoma ...of Ewing sarcoma (81). Patients with Ewing sarcoma who had very low ...
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Proximal femur reconstruction using a vascularized fibular epiphysis within a cadaveric femoral allograft in a child with Ewing sarcoma: a case report
... technique for pediatric limb salvage. Plast Reconstr Surg 2012;130:90-1. 8. Ogura M, Miyamoto S, Sakuraba M, Fujiwara T, Chuman H, Kawai A. Intercalary reconstruction after wide resection of malignant bone tumors ...
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Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma
... chemotherapy. Ewing sarcoma is a highly aggressive bone and soft tissue cancer that is caused by the EWS-FLI1 fusion ...of Ewing sarcoma to interrogate the Connectivity Map and identify ...
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Primary Vulvar Ewing Sarcoma in a 30 Year Old Woman: A Case Report
... DOI: 10.4236/crcm.2018.73022 244 Case Reports in Clinical Medicine receives monthly biphosphonate for the local bone extension. We regularly fol- lowed her with quarterly physical examination, blood test and ...
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