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Exposure Pathways

Methylmercury degradation and exposure pathways in streams and wetlands impacted by historical mining

Methylmercury degradation and exposure pathways in streams and wetlands impacted by historical mining

... provide evidence for multiple MMHg isotopic compositions within a single habitat. Further, we suggest that the bioaccumulation of these isotopically distinct MMHg pools results from the differences in feeding behavior of ...

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Assessment of Concentrations and Potential Exposure Pathways for Physiochemical Parameters near Unengineered Dumpsite in Port Harcourt, Nigeria

Assessment of Concentrations and Potential Exposure Pathways for Physiochemical Parameters near Unengineered Dumpsite in Port Harcourt, Nigeria

... This study assessed the concentrations and potential exposure pathways for physiochemical parameters near unengineered dumpsite in Port Harcourt, Nigeria. Cross sectional study was conducted on leachates, ...

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Alluvial Gold Mining Sites as Exposure Pathways for Methyl Mercury Toxicity in Children: A Systematic Review

Alluvial Gold Mining Sites as Exposure Pathways for Methyl Mercury Toxicity in Children: A Systematic Review

... of exposure to methyl mer- ...indirect exposure pathway is through breast feeding and through mothers that were exposed to dental filling with elemental mercury as documented by Daniels et ...

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Toxicologic Risk Assessment for Groundwater Constituents

Toxicologic Risk Assessment for Groundwater Constituents

... three exposure routes (ingestion, inhalation, and dermal) and via many different exposure ...these exposure pathways occur indoors ...and exposure to indoor air which is affected by ...

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Assessment Of Potential Health Risks Associated With Remediated And Non-Remediated Soils at Illegal Mining compound in Dareta, Zamfara, Nigeria.

Assessment Of Potential Health Risks Associated With Remediated And Non-Remediated Soils at Illegal Mining compound in Dareta, Zamfara, Nigeria.

... The results of the health risk assessment shows that, both carcinogenic risk and non-carcinogenic hazards posed by heavy metals to adults and children are acceptable not exceed the safety threshold, which negatively do ...

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Environmental risk assessment of genetically modified plants   concepts and controversies

Environmental risk assessment of genetically modified plants concepts and controversies

... the exposure level (delivering basic data on transgene pro- duct metabolism and biological ...critical exposure pathway can be proven to be non-existent or highly ...from exposure of aphids, that ...

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Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways

Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways

... allergen exposure may induce non- specific bronchial hyperresponsiveness (BHR) and airway inflammation ...repeated exposure to allergen on the early phase airway response however is not ...allergen ...

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Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth

Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth

... Since c-Src, Akt, and ERK1/2 in the cells were activated after nicotine treatment, it was possible that these kinases were subjected to different regulations. To test this, we treated MCF10A cells with MCA (a nAChR ...

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Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals

... after exposure in traffic [8] and mortality associated with a residential address close to major roads with dense traffic ...personal exposure to PM was associated with increased levels C-reactive protein ...

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Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways

Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways

... Our report has some limitations. First, the actually administered apixaban dose and time of drug intake are based on anamnestic information. Second, renal function was estimated using the Cockcroft-Gault equation, which ...

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The association between Parkinson’s disease and melanoma: a systematic review and meta analysis

The association between Parkinson’s disease and melanoma: a systematic review and meta analysis

... As to the risk factors of the development of melanoma, previous meta-analysis have shown family history of mel- anoma, high density of freckles, light skin color and fair hair color as major risk factors for melanoma ...

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The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-κB translocation

The apoptotic effects of <em>Brucea javanica</em> fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-&kappa;B translocation

... After exposure of HT29 cells to BJEE for 24 h, the critical proteins were implicated with cell death and apoptotic pathways were observed via human apoptosis protein ...

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Evaluation of IgE and non-IgE mediated inflammatory pathways generated through exposure to prawn proteins

Evaluation of IgE and non-IgE mediated inflammatory pathways generated through exposure to prawn proteins

... protein exposure about ...vessels. Exposure to elevated levels of airborne allergens is the key factor associated with allergic sensitisation and airway hyperresponsiveness at the workplace [1, 2] ...

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Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus

Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus

... an exposure system (“Ohio Air Pollution Exposure System for Interrogation of Systemic Effects” located at the Ohio State University Animal Facility in ...This exposure system is a mobile trailer ...

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Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure

Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure

... of exposure. For example, E8/11 exposure was associated with alterations to genes involved in cel- lular assembly, proliferation, differentiation, cell death, and tissue morphology (Table 2), even in the ...

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Reduction of Cardiac Cell Death after Helium Postconditioning in Rats: Transcriptional Analysis of Cell Death and Survival Pathways

Reduction of Cardiac Cell Death after Helium Postconditioning in Rats: Transcriptional Analysis of Cell Death and Survival Pathways

... in pathways against apoptosis and proau- tophagy; this could relate to the infarct size reduction that was observed after HePOC (15,21, 26) as well as the results from histological analysis in this ...

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Expanding the organismal proteostasis network: Linking systemic stress signalling with the innate immune response

Expanding the organismal proteostasis network: Linking systemic stress signalling with the innate immune response

... MAPK pathways is associated with an increased expression of putatively secreted immune peptides, such as C-type lectins and lysozymes, which have been proposed to activate the UPS and hence increase ...

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Impact of a single, short morning bright light exposure on tryptophan pathways and visuo- and sensorimotor performance: a crossover study

Impact of a single, short morning bright light exposure on tryptophan pathways and visuo- and sensorimotor performance: a crossover study

... OL exposure, which was not detected during BL application ...BL exposure resulted in a small increase in subjective wellbeing (affective state) in healthy subjects who were being subjected to relatively ...

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Microbial exposure alters HIV 1 induced mucosal CD4+ T cell death pathways Ex vivo

Microbial exposure alters HIV 1 induced mucosal CD4+ T cell death pathways Ex vivo

... Unlike peripheral blood or lymphoid CD4+ T cells, LP CD4+ T cells are predominantly of a recently activated, CCR5 hi effector memory phenotype [9]. These cells are highly susceptible to infection by CCR5-tropic HIV-1 ...

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DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways

DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways

... In the clinical management of CC, cancer stratification based on molecular subtyping has become an essential to guide treatment decisions [15]. Recent gene expression-based CC profiling identified four consensus ...

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