Extracellular matrix protein 1
<p>Extracellular matrix protein 1 (ECM1) is associated with carcinogenesis potential of human bladder cancer</p>
... therapy. Extracellular matrix protein 1 (ECM1) is a key player in multiple epithelial ...transporter 1 (GLUT1), lactate dehydrogenase (LDHA) and hypoxia-inducible factor 1α ...
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Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling
... fibulin-like extracellular matrix protein 1 (EFEMP1) binds to EGFR and attenuates EGFR signal- ing ...and extracellular matrix components such as laminin, collagen and ...
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Development of antigen specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus
... Lichen sclerosus is a common, acquired chronic inflammatory skin disease of unknown etiology, although circulating autoantibodies to the glycoprotein extracellular matrix protein 1 (ECM1) have ...
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Extracellular matrix protein 1 is correlated to carcinogenesis and lymphatic metastasis of human gastric cancer
... = 62.91, P <0.001; Table 2). As shown in Table 1, the protein expression of ECM1 in tumor specimen was correlated with depth of tumor invasion and TNM stage (Fisher’s exact test, P <0.001 and P = ...
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Molecular analysis of lipoid proteinosis: identification of a novel nonsense mutation in the ECM1 gene in a Pakistani family
... Histological and ultra structural examination has revealed the widespread deposition of hyaline-like mate- rial and disruption/reduplication of basement membrane around blood vessels and at the dermal-epidermal junc- ...
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Original Article Correlation of ECM1 expression level with the pathogenesis and metastasis of laryngeal carcinoma
... of extracellular matrix protein 1 (ECM1) in benign laryngeal le- sions, precancerous lesions and malignant laryngeal lesions and analyze the clinical significance of ECM1 changes in the ...
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Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease
... (AQP3), extracellular matrix protein 1 (ECM1), four and a half LIM domain 1 (FHL1), milk fat globule epidermal growth factor 8 (MFGE8, lactadherin), phosphodiesterase 4D-interacting ...
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The Extracellular Matrix of Staphylococcus aureus Biofilms Comprises Cytoplasmic Proteins That Associate with the Cell Surface in Response to Decreasing pH
... of protein interactions with the cell surface, we next determined whether a heterologous protein, FIG 2 Protein accumulation is not the result of cell lysis during sample ...for 1 h at ...
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Expression of CD147 and matrix metalloproteinase 11 in colorectal cancer and their relationship to clinicopathological features
... the extracellular matrix (ECM) and some other ...expressed protein in the stromal cells of inva- sive breast cancer compared to that of fibroadenoma as determined by subtractive hybridization ...
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Investigating the role of the extracellular matrix protein, Spondin 1, in ovarian folliculogenesis
... cell-extracellular matrix (ECM) interactions. Spondin 1 (SPON1) is an ECM protein primarily studied for its role in nervous system development as a nerve outgrowth signalling molecule, but is ...
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FEV1 inversely correlates with metalloproteinases 1, 7, 9 and CRP in COPD by biomass smoke exposure
... MMPs play an important role in the turnover of almost all extracellular matrix molecules and are there- fore probably involved in COPD pathogenesis [8,19]. An increase in serum or plasma MMP-1 and ...
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Sulforaphane has opposing effects on TNF alpha stimulated and unstimulated synoviocytes
... activator protein-1; ARE: antioxidant response element; ECM: extracellular matrix; ELISA: enzyme-linked immunosorbent assay; FCS: foetal calf serum; FLS: fibroblast-like synoviocytes; ...
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Plasma concentrations of extracellular matrix protein fibulin-1 are related to cardiovascular risk markers in chronic kidney disease and diabetes
... a 1:1000 dilu- tion and, after binding to the immobilized antibodies, were incubated with anti-human fibulin-1 IgG (mouse monoclo- nal, 3A11; Array Genetics, Newtown, Connecticut, ...
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Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7
... biotinylated protein was added to each well, except for MAdCAM-1–Fc, which was added at 100 ng per ...for 1 h at room temperature, and then, 4 g of unlabeled proteins (or a matched volume of buffer ...
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Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del 1
... The studies presented here indicate that Del-1– induced angiogenesis depends upon integrins α v β 5 and αvβ3 because genetic deletion of either integrin, as well as antagonists of these integrins, inhibit ...
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2.Membranes
... Fibers of extracellular matrix (ECM) Glycoprotein Carbohydrate Microfilaments of cytoskeleton Cholesterol Integral protein Peripheral proteins CYTOPLASMIC SIDE OF MEMBRANE EXTRACELLULAR [r] ...
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Composite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration
... single cell type, the cell sheet that comprises these two types of stem cells shows stronger osteogenic potential, which is beneficial to the functional regeneration of peri- odontal tissue. Furthermore, the expression ...
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The role of aggrecan in normal and osteoarthritic cartilage
... In the early stages of OA, prior to extensive collagen damage, it may be possible to retard or even reverse the degenerative process by the administration of agents that promote aggrecan synthesis and prevent its ...
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Role of TGFBIp in Wound Healing and Mucin Expression in Corneal Epithelial Cells
... Fig. 1. TGFBIp increases the migration, adhesion, proliferation, and wound healing of SV40-CECs. (A and B) Effect of TGFBIp on SV40-CECs migration. SV40-CECs were treated with TGFBIp or fibronectin and migration ...
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Essential role of mitogen activated protein kinases in IL 17A induced MMP 3 expression in human synovial sarcoma cells
... time-dependent manner. Activation occurred within 180 min (Fig. 3a), whereas IL-17A had no effect on NF-κB activation, as evidenced by phosphorylation (P-IκB-α) or degradation of IκB-α (Fig. 3b). To determine the role of ...
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