extremely drug resistant (xdr)
Rapid identification of extensively and extremely drug resistant tuberculosis from multidrug resistant strains; using PCR-RFLP and PCR-SSCP.
... respectively) and inactivate it (7). The quinolone- resistance determining region (QRDR) of the gyrA and gyrB genes is the conserved region and mutation in this region is responsible for resistance to FQs. Mutation were ...
6
An outbreak of extremely drug resistant Pseudomonas aeruginosain a tertiary care pediatric hospital in Italy
... Under high antimicrobial pressure, there is a risk of polyclonal emergence of multiple-antibiotic-resistant P. aeruginosa. Use of broad-spectrum cephalosporins and of aminoglycosides antibiotics have been ...
8
Impact of colistin plasma levels on the clinical outcome of patients with infections caused by extremely drug resistant Pseudomonas aeruginosa
... The drug was administered intra- venously in 100 mL of normal saline over 30 min in the commercially available colistimethate formulation for in- jection (GES GenéricosEspañoles®), with each vial con- taining 80 ...
9
Multi-Drug Resistant Tuberculosis (MDR-TB) and its drug Treatment
... of Extremely Drug Resistant TB (XDR-TB), a form of Multi Drug Resistant TB where the ...is resistant not only to the first line anti TB agents but also to the second line anti TB ...
6
Design, Synthesis and Evaluation of Linked Pyridinyl-Oxadiazoles as Treatment of XDR and MDR Tuberculosis-Part II
... Recently, Mycobacterium tuberculosis (MTB) strains have transformed from about to be eradicated to most resistant microbe, thank to Multi- drug resistant (MDR) and extremely drug ...
7
Neuroimaging in drug resistant epilepsy
... have drug resistant epilepsy if disabling seizures continue despite appropriate trials of two anti-epileptic ...causing drug resistant epilepsy can be detected by 3T MR Imaging using dedicated ...
7
Linezolid for drug-resistant tuberculosis
... of drug-re- sistant TB suggest linezolid as a “group C: other core second-line agent”, and recommend that two such drugs are required within a core drug-resistant TB regimen (WHO ...
12
“Potential Threat of New Delhi Metallo-Beta-Lactamase-1 Enzyme, Multi Drug Resistant and Extensive Drug Resistant (XDR) to Achieve the Millennium Development Goals (MGD’S) in South East Asian Countries” by Taha Nazir, Saeed Ur Rashid Nazir, Azharul Islam, Misbah Sultana, Humayun Riaz, Nida Taha, Canada.
... The research manuscripts were selected Medline, Embase, PubMed, Cochrane Central Register of Controlled Trials, International Pharmaceutical abstracts, Cumulative Index to Nursing, and Allied Health Literature and Latin ...
7
Treatment of drug-resistant tuberculosis
... of drug-resistant TB is made by performing drug-susceptibility testing (DST) of the strain of TB obtained from the ...of drug-resistant TB based on the profiles mentioned above should ...
7
The Emergency of Drug Resistant Pathogens
... As another example, a new extended- spectrum β-lactamase (CTX-M) clinically significant level. The CTX-M genes and subsequent variants (upwards of 100 different amino acid substitutions have been identified so far) are ...
25
Tuberculosis Drug Resistance: An Overview
... countries. Drug resistance in tuberculosis was observed early as 50 years ago, the response of patient with MDR-TB to treatment is poor and mortality rate is usually high ...totally drug resistant ...
11
High Throughput Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as an Alternative Approach to Monitoring Drug Resistance of Hepatitis B Virus
... of drug-resistant HBV ...identifying drug-resistant HBV YMDD variants was developed and turned out to be more sensitive than INNOLiPA HBV DR and direct ...
6
Iontophoresis: An Electrically Assisted Drug Delivery System
... At present, the most common form of delivery of drugs is the oral route. While this has the notable advantage of easy administration, it also has significant drawbacks namely poor bioavailability due to hepatic ...
12
Drug Resistant Epimutants Exhibit Organ Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides
... The plates were imaged after 16 h of growth, and FK506-resistant (hyphal) versus FK506-sensitive (yeast) colonies were counted. All colonies grew as hyphae on nonse- lective YPD under normoxic conditions, as ...
11
Counting the lives saved by DOTS in India: a model-based approach
... treatment. When it was launched in 1997 to replace the erstwhile National Tuberculosis Programme (NTP), its purpose was to reform and coordinate TB services on a national level, in line with DOTS standards of TB care. In ...
10
Surface colonization and subsequent development of infections with multi drug resistant organisms in a neonatal intensive care unit
... The findings in our study along with the existing evi- dences emphasize the gastrointestinal tract and other body surfaces to be essentially sterile at birth and is subsequently colonized by microbes acquired from the ...
7
Invitro synergistic activity of lactic acid bacteria against multi drug resistant staphylococci
... their territory by secreting acids like lactic, acetic, for- mic, succinic, glutamic, citric, and butyric acids; thereby creating an environment which is inhospitable to disease-causing bacteria. Lactobacilli are known ...
8
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.
... Drug profiling analysis of in A204 parental and resistant cell lines. 879[r] ...
36
Prevalence and genetic characterization of carbapenem and polymyxin resistant acinetobacter baumanniiIsolated from a tertiary hospital in Terengganu, Malaysia
... It is interesting that the 14 polymyxin-resistant isolates displayed an identical P102H mutation within the pmrA gene and this mutation was identical to that previously reported by Adams et al. (2009) [10] in a ...
10
World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malaria
... measuring drug efficacy, but when assays for molecular resistance markers are sufficiently predictive of clinical treatment outcomes, their simplicity, robustness and scal- ability make them a potentially powerful ...
10