Fasciola hepatica excretory–secretory products
Leucine Aminopeptidase Is an Immunodominant Antigen of Fasciola hepatica Excretory and Secretory Products in Human Infections
... Identification of F. hepatica immunogenic proteins in ESP detected by human sera from an area in which fasciolosis is endemic. To investigate the antigenicity of the ESP proteins, we used sera from patients ...
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Triclabendazole (Anthelmintic Drug) Effects on the Excretory- Secretory Proteome of Fasciola hepatica in Two Dimension Electrophoresis Gel.
... laboratory. Fasciola hepatica parasites were isolated, washed 6 time in PBS ...F. hepatica treated with ...ES products were collected, and centrifuged for 10 minutes at 25 ˚C at 13000 ...
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Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni
... anti-Fasciola hepatica leucine aminopep- tidase (LAP; 1/4,000), kindly provided by ...anti-F. hepatica cathepsin L1 (1/ 1,000), kindly provided by professor ...
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Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis
... E/S products contained a wide spectrum of proteins from 20–220 kDa in ...a Fasciola hepatica cathepsin L has also been shown to have immunomodulatory properties by sup- pressing ovine T-lymphocyte ...
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Suppression of ovine lymphocyte activation by Teladorsagia circumcincta larval excretory-secretory products
... ES products and somatic extracts from ...tode, Fasciola hepatica, has been shown to be capable of suppressing mitogen-induced proliferation of both ovine and human lymphocytes ...
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DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo dendritic cells
... termed excretory/ secretory products ...F. hepatica (FgESPs or FhESPs) caused host antigen-presenting cells (APCs) to remain immature, and downregulated the expression of toll-like receptors ...
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Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni
... anti-Fasciola hepatica leucine aminopep- tidase (LAP; 1/4,000), kindly provided by ...anti-F. hepatica cathepsin L1 (1/ 1,000), kindly provided by professor ...
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Protein Detection of Excretory-Secretory Products and Somatic Extracts from Fasciola hepatica and F. gigantica Using Two-Dimensional Electrophoresis
... Two-dimensional electrophoresis was ac- complished for both ES materials and somatic extracted solutions of Fasciola species. For first dimension, IEF tubes were washed with sulphochromic acid, and then rinsed ...
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Complete mitochondrial genomes of the ‘intermediate form’ of Fasciola and Fasciola gigantica, and their comparison with F hepatica
... F. hepatica (NC_002546) [26] [Fasciolidae]; Clonorchis sinensis (GeneBank accession ...of Fasciola sp.. F. gigantica and F. hepatica were aligned (over a consensus length of 359 bp) using MUSCLE, the ...
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Studies on the metacercaria of Fasciola hepatica L. : encystment and excystment
... Sections: A phase contrast study of unstained paraffin and frozen sections revealed the same general shape and structure as was seen in the whole mounts except that no subdivision of the[r] ...
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Fasciola hepatica Pseudosuccinea columella interaction: effect of increasing parasite doses, successive exposures and geographical origin on the infection outcome of susceptible and naturally resistant snails from Cuba
... F. hepatica in susceptible ...F. hepatica. Conversely, F. hepatica transmis- sion in France is mainly related to other snails ...F. hepatica isolates and might bring a deeper understanding on ...
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Development of a multiplex fluorescence immunological assay for the simultaneous detection of antibodies against Cooperia oncophora, Dictyocaulus viviparus and Fasciola hepatica in cattle
... [29] (sensitivity and specificity >99 %) as well as Gozdzik et al. [27] (sensitivity 97.7 %, specificity 98.1 %) for ELI- SAs using the same recombinant antigen, a few MFI values obtained for sera from animals ...
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Immunoproteomic analysis of the excretory secretory products of Trichinella pseudospiralis adult worms and newborn larvae
... ES products are very similar but are not identical in cDNA se- quence, molecular mass, antigenicity and peptide maps of ES products [12 – ...ES products are considered to be directly exposed to the ...
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Spatial patterns of Fasciola hepatica and Calicophoron daubneyi infections in ruminants in Ireland and modelling of C daubneyi infection
... consistently been reported to have activity against imma- ture and adult worms is oxyclozanide [29, 30] while there is a single report of closantel being effective after oral administration [30]. Current recommendations ...
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Prevalence of gastrointestinal nematodes and Fasciola hepatica in sheep in the northwest of Spain: relation to climatic conditions and/or man made environmental modifications
... The infections caused by helminth parasites are very common in ruminants worldwide but principally they are present in areas with enough humidity for the devel- opment of free-living stages of the life cycle. The preva- ...
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Identity of Fasciola spp in sheep in Egypt
... In a ML analysis of the nad1 sequences, all F. gigantica haplotypes from this study clustered with those derived from several hosts from Egypt, forming a distinct hap- logroup (designated as haplogroup D). This ...
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Liver fluke in Irish sheep: prevalence and associations with management practices and co infection with rumen fluke
... categorical variable. Wilcoxon signed-rank test was applied for comparing the total sum of eggs per gram per region. Pearson’s chi-square, Wilcoxon test and final regression models were carried out using Stata 13. All ...
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Cryptic intermediate snail host of the liver fluke Fasciola hepatica in Africa
... Despite its patchy continental distribution, G. mweru- ensis is well established, especially in the extensive sub-ranges (Fig. 1). We here confirmed its presence in regions where it has not been observed for decades such ...
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Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway
... ES products to pass through and directly interact with the immune cells around the cyst [32, ...ES products, can induce arginase expression in vitro and enhance the induction of Ym1 expression in vivo, ...
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... Human Fascioliasis (HF) is a foodborne neglected parasitic disease caused by Fasciola hepatica and Fasciola gigantica. New epidemiological data suggest that the endemic areas of the disease are ...
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