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feedback regulation / ribosomes / RNA secondary structure / translation

RNA Secondary Structure in the Coding Region of Dengue Virus Type 2 Directs Translation Start Codon Selection and Is Required for Viral Replication

RNA Secondary Structure in the Coding Region of Dengue Virus Type 2 Directs Translation Start Codon Selection and Is Required for Viral Replication

... which ribosomes recognize start codons has been mapped not only to basepairing with the initiator tRNA-Met anticodon, but also to initiation factors, such as eIF1 and eIF1a, which dissociate improperly formed ...

13

RNA thermosensors: how might animals exploit their regulatory potential?

RNA thermosensors: how might animals exploit their regulatory potential?

... The secondary and tertiary orders of RNA structure are crucial for a suite of RNA-related functions, including regulation of translation, gene expression and RNA ...of ...

7

Genome-Wide Analysis of RNA Secondary Structure in Eukaryotes

Genome-Wide Analysis of RNA Secondary Structure in Eukaryotes

... the secondary structure of full-length ...mRNA secondary structures are available, but they suffer from limited ...of secondary structure, such as the decreased base pairing at sites of ...

141

trans Regulation of Cap-Independent Translation by a Viral Subgenomic 
RNA

trans Regulation of Cap-Independent Translation by a Viral Subgenomic RNA

... known secondary structure of the BYDV gRNA 5 ⬘ UTR (21) and the MFOLD-predicted (58) secondary structure of the sgRNA1 5 ⬘ ...on translation of A-GfLUC, GfLUC, and SG1fLUC in wheat germ ...

10

Translating Ribosomes Inhibit Poliovirus Negative-Strand RNA Synthesis

Translating Ribosomes Inhibit Poliovirus Negative-Strand RNA Synthesis

... of translation by binding to the viral RNA outside the core ...that translation initiation might be regulated by viral proteins binding to sequences in the poliovirus genome that are not part of the ...

9

Autogenous regulation of RNA translation and packaging by Rous sarcoma virus Pr76gag.

Autogenous regulation of RNA translation and packaging by Rous sarcoma virus Pr76gag.

... perturb RNA secondary structure, the methods used to quantify packaging and translation, and the use of two different strains of ...that translation of ORF3 is important to ...the ...

11

RNA-Based Regulation of Transcription and Translation of Aureusvirus Subgenomic mRNA1

RNA-Based Regulation of Transcription and Translation of Aureusvirus Subgenomic mRNA1

... introduced RNA hairpin would provide an appropriately positioned artificial version of the required AS1-RS1 element ...mfold-predicted secondary structure for CLSV genome sequence that includes the ...

10

Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation

Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation

... of RNA into divergent structures is constrained by specific RNA sequences under physiological condi- ...sequence-and structure- specific manners, mimicking an open promoter struc- tures and ...

8

Genomic RNA of mengovirus. VI. Translation of its two cistrons in lysates of interferon-treated cells.

Genomic RNA of mengovirus. VI. Translation of its two cistrons in lysates of interferon-treated cells.

... The sequences of mengovirus RNA recognized by ribosomes of interferon-treated cells at initiation of translation were compared with those present in initiation complexes formed by riboso[r] ...

6

The maternal to zygotic transition revisited

The maternal to zygotic transition revisited

... To distinguish between maternal and zygotic transcripts that are often present at the same time, zygotic contributions have been removed by transcription inhibition (Lee et al., 2013), the use of chromosomal deficiencies ...

20

Functional analysis of the Tat trans activator of human immunodeficiency virus type 2.

Functional analysis of the Tat trans activator of human immunodeficiency virus type 2.

... This RNA secondary structure displays an additional loop within the predicted TAR recognition sequence, and it has been suggested that a requirement for recognition of two such structure[r] ...

7

Secondary structure of RNA from bacteriophages f2 Qbeta, and PP7.

Secondary structure of RNA from bacteriophages f2 Qbeta, and PP7.

... The former structure is not seen with the partially denaturing conditions that we used for electron microscopy, but the latter structure corresponds closely to the stem of the central op[r] ...

7

Secondary Structural Elements within the 3′ Untranslated Region of Mouse Hepatitis Virus Strain JHM Genomic RNA

Secondary Structural Elements within the 3′ Untranslated Region of Mouse Hepatitis Virus Strain JHM Genomic RNA

... DI RNA replication assays to examine the role of RNA secondary structure within the 3⬘-terminal 166 nt of the MHV-JHM genome in ...larger RNA molecule and to explore their biological ...

9

Translation Initiation Factor eIF4B Interacts with a Picornavirus Internal Ribosome Entry Site in both 48S and 80S Initiation Complexes Independently of Initiator AUG Location

Translation Initiation Factor eIF4B Interacts with a Picornavirus Internal Ribosome Entry Site in both 48S and 80S Initiation Complexes Independently of Initiator AUG Location

... The identity of the eIF4B protein interacting with the IRES RNA in the initiation complexes was verified by immunopre- cipitation (Fig. 2C). By using the UV cross-linking assay, only eIF4B molecules in the RRL ...

10

Optimal management of nutrient reserves in microorganisms under time varying environmental conditions

Optimal management of nutrient reserves in microorganisms under time varying environmental conditions

... 1 feedback loops, one between each reserve density and the allocation of molecular building blocks towards the machinery dedicated to the assimilation of that nutrient, in addition to a basic growth-control loop ...

41

COMPARISON OF PLACENTAS FROM TWO SOCIOECONOMIC GROUPS. II. BIOCHEMICAL CHARACTERISTICS

COMPARISON OF PLACENTAS FROM TWO SOCIOECONOMIC GROUPS. II. BIOCHEMICAL CHARACTERISTICS

... In vitro protein synthetic capacity per unit of RNA was not different in the two groups, although this proportion of ribosomes recovered as polysomes was lower in the Guatemalan series..[r] ...

9

Ribosomes

Ribosomes

... 10,000 ribosomes which make upto 30% of the weight of the ...bacterial ribosomes are present free in the ...messenger RNA during translation and ...the ribosomes function as peptidyl ...

5

Biochemical and genetic evidence for a pseudoknot structure at the 3' terminus of the poliovirus RNA genome and its role in viral RNA amplification.

Biochemical and genetic evidence for a pseudoknot structure at the 3' terminus of the poliovirus RNA genome and its role in viral RNA amplification.

... RNA secondary structure analysis by chemnical and enzymatic probing of mutant 3NC202 and revertant R9 3'-terminal RNA transcripts demonstrated that PK formation was impaired in 3NC202 RN[r] ...

11

ZFAS1: a long noncoding RNA associated with ribosomes in breast cancer cells

ZFAS1: a long noncoding RNA associated with ribosomes in breast cancer cells

... with ribosomes remains unknown, although those few that have been studied in detail have been found to regulate translation by associating with the polysomes during stress conditions and regulating the ...

25

Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection

Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection

... We next determined whether these RNA structure dif- ferences are involved in viral replication. We rescued 4 influenza viruses that have predicted combinations of NS gene RNA secondary ...

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