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Tumour regression and improved gastrointestinal tolerability from controlled release of SN 38 from novel polyoxazoline modified dendrimers
... Dend-SN38 pharmacokinetics To determine the plasma SN-38 concentrations achieved by the Dend-SN38 conjugates with different release rates, naive female nude mice n = 2/group were injecte[r] ...
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The gendered image: deconstructing life drawing.
... dominant until the early 1970s when feminist theory and practice, stemming from the second wave feminist movement challenged Clark’s position with an alternative set of assumptions .The essential differences between ...
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Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice
... Notes: Female nude mice (n = 3) bearing A2780 ovarian cancer xenografts (approximately 800 mm 3 ), administered a single intravenous tail vein injection of free cisplatin [r] ...
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<p>Sonophoresis Enhanced Transdermal Delivery of Cisplatin in the Xenografted Tumor Model of Cervical Cancer</p>
... Thirty-two female nude-mice model of cervical cancer were randomly divided into 4 groups (n=8 in each group): control group without any intervention, low, medium and high concentration groups were treated ...
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HAase-sensitive dual-targeting irinotecan liposomes enhance the therapeutic efficacy of lung cancer in animals
... xenografted female nude mice, the bone marrow indicators (WBC, Hb, and PLT) are mildly decreased, suggesting that GE11/HA/TATp-irinotecan liposomes may have no significant influences on bone marrow (Figure ...
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PubMedCentral-PMC5035646.pdf
... bearing female SPF C3H/HeNcrj mice and nude mice respectively is only 2–3× higher compared to Taxol ...balb/c female nude mice but only at a rather low concentration ...
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Enigmatic (?) friezes on Praenestine cistae
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Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms
... in nude rats and severe combined immunodeficient (SCID) mice who had no T cells, while Gly reduced infarction in both nude rats and SCID mice whose T cells were reconstituted, suggesting that T cells should ...
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Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ
... The mutant protein dmrFABP5 has a very similar structure to that of wtrFABP5, but the mutant is almost incapable of binding to fatty acids, as shown in Figure 1C and 1D. Here for the first time, we have shown that ...
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FOXN1 deficient nude severe combined immunodeficiency
... with nude SCID may have features of Omenn Syndrome (OS) [1, 23, 26], an in- flammatory condition caused by expansions auto-reactive T-cells in the setting of SCID and characterised by erythro- derma, ...
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A matrixial gaze : portrayals of the male nude by female artists
... However, many of her paintings also reflect references to other well-known historical paintings. She is incorporating traces of these works and in a way, sustaining them whilst reconsidering them. This work probably ...
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Original Article Small interfering RNA survivin and GRIM-19 co-expression salmonella plasmid inhibited the growth of laryngeal cancer cells in vitro and in vivo
... the nude mice were killed, and the tumor, heart, liver, lung, kidney and spleen were collection for the detection of bacterial colo- ...in nude mice, in the psi-survivin group, p-GRIM-19 group and p-siRNA ...
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Stromelysin 3 expression promotes tumor take in nude mice
... 100%, respectively, demonstrating their high propensity to im- plant and proliferate into nude mice. Surprisingly, the second control clone, 3T3/14.3, did not give rise to any tumor until 6 wk after cell ...
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MiR-139-5p/SLC7A11 Inhibits the Proliferation and Migration of Pancreatic Carcinoma via PI3K/Akt Signaling Pathway
... in PANC has not been focused. In our study, we confirmed that miR-139-5p was lowly expressed in both PANC tissues and cells. Through functional analysis, overexpression of miR-139-5p significantly inhibited PANC cell ...
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Indocyanine green-incorporating nanoparticles for cancer theranostics
... generate intracellular singlet oxygen to kill tumor cells [70]. Photosensitisers can selectively target tumor cells to reduce side effects on normal cells, and photodynamic therapy does not induce any chemoresistance, ...
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Heterotopic erotic oases - the public nude beach experience
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Artificial zona pellucida for in vivo culture of nude blastomeres
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Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway
... Tumor recurrence remains an obstacle after liver surgery, especially in living donor liver transplantation (LDLT) for patients with hepatocellular carcinoma (HCC). The acute-phase liver graft injury might potentially ...
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BMX-ARHGAP fusion protein maintains the tumorigenicity of gastric cancer stem cells by activating the JAK/STAT3 signaling pathway
... a Tumor volume and weight in nude mice injected with transfected SGC7901 cells; b protein expression of CD133, CD44, SOX2 and Nanog in the tumor tissues of nude mice injected with t[r] ...
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