fibroblast-like cell
Osteoclast independent bone resorption by fibroblast like cells
... animals using a stereostactic device. For running exercise, the electrodes were connected to the running wheel (diameter 25 cm; width 8 cm) through an electronic switch. While running in the wheel, the rats received ...
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Characterization of fibroblast like cells from the rat olfactory bulb
... The cell suspension of olfactory bulb tissue was harvested from rats (n=10) and plated into plastic cell culture plate in DMEM/ F12 containing 10% fetal bovine serum (FBS; Sigma), 2mm L- glutamine (Gibco, ...
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The inhibitory activity of human interleukin 1 receptor antagonist is enhanced by type II interleukin 1 soluble receptor and hindered by type I interleukin 1 soluble receptor
... monocytes/macrophages. At the inflammatory site, IL-1 is a potent inducer of the production of prostaglandin E2 (PGE2) and metalloproteinases on fibroblast-like cells, thus triggering tissue damage. The ...
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An Orphan G Protein-Coupled Receptor, GPR1, Acts as a Coreceptor To Allow Replication of Human Immunodeficiency Virus Types 1 and 2 in Brain-Derived Cells
... brain-derived fibroblast-like cell strains BT-3 and BT-20/N were further isolated (38, 41, ...primary cell strains stop growing when they are passaged more than 10 to 15 ...morphologically ...
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Canine Periodontal Stem Cells: Isolation, Differentiation Potential and Electronic Microscopic Characterization
... single cell suspension of canine PDL cells was plated in 25-cm 2 culture flasks under specific culture ...clonogenic cell clusters of fibroblast-like cells, similar to those recorded for human ...
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Fibroblast biology Signals targeting the synovial fibroblast in arthritis
... direct cell–cell contacts more or less permanently modulate the pheno- type and function of fibroblast-like cells in the synovial lining, stroma and ...
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Fibroblast activation protein is expressed by rheumatoid myofibroblast like synoviocytes
... II cell surface serine protease expressed by fibroblastic cells in areas of active tissue remodelling such as tumour stroma or healing ...by fibroblast-like synoviocytes (FLSs) and compared the ...
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Chemerin activates fibroblast like synoviocytes in patients with rheumatoid arthritis
... from Cell Sig- naling Technology), mouse anti-phospho-JNK mAb (1:300 dilution; Santa Cruz Biotechnology, Santa Cruz, CA, USA), rabbit anti-pan-JNK pAb (1:1, 000 dilution), rabbit anti- phospho-Akt pAb (1:2, 000 ...
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Ecotropic murine leukemia virus-induced fusion of murine cells.
... Cell lines used in this study Cell line B559 Mouse fibroblast Mouse, transformed fibroblast Mouse fibroblast Mouse fibroblast Mouse fibroblast Mouse fibroblast Mouse fibroblast Mouse fib[r] ...
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Fibroblast like synoviocytes support B cell pseudoemperipolesis via a stromal cell–derived factor 1– and CD106 (VCAM 1)–dependent mechanism
... B cells from undergoing spontaneous apoptosis through a contact-dependent mechanism requiring VLA-4 interactions with CD106 expressed on FLSs (28). The present study demonstrates that the CXC chemokine SDF-1 and its ...
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Rationale for targeting VEGF, FGF, and PDGF for the treatment of NSCLC
... nonsmall cell lung cancer (NSCLC), having a 5-year survival rate of less than ...VEGF, fibroblast growth factor, platelet-derived growth factor, and their ...
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Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast like synoviocytes from nitric oxide induced apoptosis
... various cell types and under different conditions, several other studies have shown that the overexpression of Hsp70 promotes cell death, which suggests that Hsp70 has dual functionality depending on ...
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Neoplastic Like CELL Changes of Normal Fibroblast Cells Associated with Evolutionary Conserved Maternal and Paternal Genomic Autonomous Behavior (Gonomery)
... transformed cell-growth was apparent in extended proliferation (Figure 3(A), Figure 3(B)), when the patterns of growth were hyperplastic-like and mul- ti-layered focal areas with cell polarity and ...
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Epidermal Growth Factor Receptor Is Not Required for Human Cytomegalovirus Entry or Signaling
... cancer cell line (MB453) was resistant to HCMV infec- tion, whereas an EGFR-positive human breast cancer cell line (MB468) was permissive for viral gene expression ...EGFR-expressing cell lines, we ...
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Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1.
... We reported previously that CMV infection of fibroblasts induces a basic fibroblast growth factor-like factor 2 which can stimulate endothelial cell proliferation, thus supporting the po[r] ...
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Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast like synovial cells
... mononuclear cell infiltration and overex- pression of proinflammatory mediators (such as TNF-α and NFκB) were seen in synovium during the early phase of the disease, which may reflect increased activation of ...
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PADI4 Epigenetically Suppresses p21 Transcription and Inhibits Cell Apoptosis in Fibroblast-like Synoviocytes from Rheumatoid Arthritis Patients
... Citrullination of the proteins leads to significant changes in their biological activity, such as the regulation of cell proliferation and apoptosis [9, 10]. Histones H3 and H4 are the first substrate proteins ...
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Endothelial cell-fibroblast interactions in scleroderma
... endothelial cell products expressed on the cell surface or released from endothelial cells in response to a variety of ...mixed cell populations has permitted the culture of other human endothelial ...
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Glutaminase 1 plays a key role in the cell growth of fibroblast like synoviocytes in rheumatoid arthritis
... We next examined the roles of HK2, MCT4, PDK1, and GLS1 in RA-FLS proliferation. Smaill interfering RNA (siRNA) efficiency is shown in Additional file 4: Figure S3. The knockdown of MCT4, PDK1, or GLS1, but not HK2, ...
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The synovial proteome: analysis of fibroblast like synoviocytes
... endothelial cell lines also results in enhanced expression of vascular endothelial growth factor providing a link for neovascularization of the synovium ...
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